Abstract
Basal Ganglia (BG) are functional areas within human brain that are target for various deep brain stimulation (DBS) surgeries. During DBS surgery a permanent stimulating electrode is placed within selected part of the BG. One of the methods of localization of the selected part of the BG is based upon analysis of recordings obtained from BG using thin neurosurgical microelectrodes. This paper shows method for obtaining the minimal frequency ranges required for detection of the STN (\(Subthalamic\;Nucleus\)) area of the BG as well as frequencies that can be used for detection of another BG area denoted as SNr (\(Substantia\;Nigra\;pars\;reticulata\)). The recorded signal is analyzed in separate 100 Hz bands to find a subset of them that provides good basis for classification of recordings. It is shown that already a continuous block of five such bands is sufficient to discriminate STN recordings with both sensitivity and specificity above 0.92. It is also shown that results obtained from some of those bands, show distinct differences between signals obtained from STN and SNr.
References
Ciecierski, K., Mandat, T., Rola, R., Raś, Z.W., Przybyszewski, A.W.: Computer aided subthalamic nucleus (STN) localization during deep brain stimulation (DBS) surgery in Parkinson’s patients. Ann. Acad. Medicae Silesiensis 5, 275–283 (2014)
Kohavi, R.: A study of cross-validation and bootstrap for accuracy estimation and model selection. In: IJCAI (1995). https://pdfs.semanticscholar.org/0be0/d781305750b37acb35fa187febd8db67bfcc.pdf
Israel, Z., Burchiel, K.J.: Microelectrode Recording in Movement Disordersurgery. Thieme, Stuttgart (2011)
Lior, R., et al.: Data Mining with Decision Trees: Theory and Applications, vol. 81. World Scientific, Singapore (2014)
Mandat, T.S., Hurwitz, T., Honey, C.R.: Hypomania as an adverse effect of subthalamic nucleus stimulation: report of two cases. Acta Neurochir. 148(8), 895–898 (2006)
Nieuwenhuys, R., Voogd, J., Van Huijzen, C.: The Human Central Nervous System: A Synopsis and Atlas. Springer, Heidelberg (2007). https://doi.org/10.1007/978-3-540-34686-9
Wan, K.R., Maszczyk, T., See, A.Q.A., Dauwels, J., King, N.K.K.: A review on microelectrode recording selection of features for machine learning in deep brain stimulation surgery for Parkinson’s disease. Clin. Neurophysiol. (2018). https://doi.org/10.1016/j.clinph.2018.09.018. https://linkinghub.elsevier.com/retrieve/pii/S1388245718312409
Sun, Y., Kamel, M.S., Wong, A.K., Wang, Y.: Cost-sensitive boosting for classification of imbalanced data. Pattern Recognit. 40(12), 3358–3378 (2007). https://doi.org/10.1016/J.PATCOG.2007.04.009. https://www.sciencedirect.com/science/article/abs/pii/S0031320307001835
Blackwelder, W.C.: “Proving the null hypothesis” in clinical trials. Control. Clin. Trials 3(4), 345–353 (1982). https://www.sciencedirect.com/science/article/pii/0197245682900241
Young, I.T.: Proof without prejudice: use of the Kolmogorov-Smirnov test for the analysis of histograms from flow systems and other sources. J. Histochem. Cytochem. 25(7), 935–941 (1977). https://doi.org/10.1177/25.7.894009
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this paper
Cite this paper
Ciecierski, K.A. (2019). Narrow Band-Based Detection of Basal Ganglia Subterritories. In: Rutkowski, L., Scherer, R., Korytkowski, M., Pedrycz, W., Tadeusiewicz, R., Zurada, J. (eds) Artificial Intelligence and Soft Computing. ICAISC 2019. Lecture Notes in Computer Science(), vol 11509. Springer, Cham. https://doi.org/10.1007/978-3-030-20915-5_13
Download citation
DOI: https://doi.org/10.1007/978-3-030-20915-5_13
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-20914-8
Online ISBN: 978-3-030-20915-5
eBook Packages: Computer ScienceComputer Science (R0)