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Practical Considerations in Management of Non-eosinophilic Asthma

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Difficult To Treat Asthma

Part of the book series: Respiratory Medicine ((RM))

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Abstract

Asthma is heterogeneous disease that can be broadly classified into eosinophilic and non-eosinophilic asthma based on sputum and or blood eosinophils. Noneosinophilic asthma can be further subdivided by predominant inflammatory cell types: neutrophilic, mixed granulocytic, and paucigranulocytic asthma. Patients with non-eosinophilic asthma represent approximately half of all asthma cases in adults and have been shown to have the full spectrum of disease, ranging from mild to severe asthma. Non-eosinophilic asthma accounts for approximately half of all asthma cases, however because its mechanisms are not well understood there are a lack of available therapies targeted to this population. This chapter discusses the major phenotypes of Non-eosinophilic and current treatment approaches.

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Authors and Affiliations

  1. Department of Medicine, Division of Pulmonary Sciences and Critical Care, University of Colorado, Denver, CO, USA

    Meghan Althoff

  2. Asthma Clinical & Research Programs, Pulmonary Sciences and Critical Care, University of Colorado, Denver, CO, USA

    Fernando Holguin

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  1. Meghan Althoff
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  2. Fernando Holguin
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Correspondence to Fernando Holguin .

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  1. Mary Parkes Center for Asthma, Allergy & Pulmonary Care, University of Rochester School of Medicine, Rochester, NY, USA

    Sandhya Khurana

  2. Asthma Clinical & Research Programs Pulmonary Sciences and Critical Care, University of Colorado, Denver, CO, USA

    Fernando Holguin

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Althoff, M., Holguin, F. (2020). Practical Considerations in Management of Non-eosinophilic Asthma. In: Khurana, S., Holguin, F. (eds) Difficult To Treat Asthma. Respiratory Medicine. Humana, Cham. https://doi.org/10.1007/978-3-030-20812-7_11

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