Mycoplasma genitalium

  • Steven A. ElsesserEmail author
  • Helen C. Koenig


Mycoplasma genitalium is a bacterial cause of non-gonococcal urethritis (NGU) among men and cervicitis and pelvic inflammatory disease (PID) among women. In the United States, the prevalence of M. genitalium is approximately 1% in the general population of young adults, making M. genitalium more common than Neisseria gonorrhoeae infection, though less common than Chlamydia trachomatis. M. genitalium is estimated to account for 20–35% of non-chlamydial NGU cases among males. It is not visible on Gram stain due to lack of a cell wall, and its fastidious nature renders culture difficult. As such, the only current diagnostic test available for M. genitalium is nucleic acid amplification testing (NAAT) using PCR. Although first identified in 1981, M. genitalium is often referred to as an emerging sexually transmitted infection (STI) as PCR detection of the organism has only recently become available, and remains unavailable in many clinical settings.


Mycoplasma genitalium M. genitalium Youth Sexually transmitted infections (STIs) Bacterial infection Non-gonococcal urethritis Cervicitis Pelvic inflammatory disease (PID) 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Family Medicine and Community HealthUniversity of PennsylvaniaPhiladelphiaUSA
  2. 2.Division of Infectious Diseases Hospital of the University of Pennsylvania, PrEP Program, Philadelphia FIGHTPhiladelphiaUSA

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