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Implementing Tissue Engineering and Regenerative Medicine Solutions in Silicone Implants

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Regenerative Medicine and Plastic Surgery

Abstract

Approaches from regenerative medicine with respect to medical implants are somewhat novel concepts. The chapter is an introduction to the problems of interfacing biological tissue and silicone implants. The authors discuss problems associated with medical implants, suppression of cysteinyl leukotriene to reduce capsular contracture around silicone implants, problems associated with silicone implants and biointegration, overview of solid implant types, solid implant complications, complications seen in particular implant locations, principles and techniques for avoidance of postoperative complications, and preoperative antibiotic soak or impregnation. The objective of this chapter was to inform readers about the possibilities of learning from and adopting from concepts that are still in their nascent stages of development in tissue engineering and regenerative medicine to achieve total and permanent integration between silicone implants and surrounding biological tissues. In particular, we focus on an exploration of the application of silicone implants for reconstructive surgery and tissue engineering.

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Authors and Affiliations

  1. Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Republic of Korea

    Jae Chul Lee & Chan Yeong Heo

  2. Department of Plastic Surgery, College of Medicine, Interdisciplinary Program in Bioengineering, College of Engineering, Seoul National University, Seoul, Republic of Korea

    Chan Yeong Heo

Authors
  1. Jae Chul Lee
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  2. Chan Yeong Heo
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Editors and Affiliations

  1. Department for Plastic Surgery and Hand Surgery, Division of Experimental Plastic Surgery, Technical University of Munich, Munich, Germany

    Dominik Duscher

  2. Private Practice, Tustin, CA, USA

    Melvin A. Shiffman

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Lee, J.C., Heo, C.Y. (2019). Implementing Tissue Engineering and Regenerative Medicine Solutions in Silicone Implants. In: Duscher, D., Shiffman, M.A. (eds) Regenerative Medicine and Plastic Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-19958-6_26

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