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Biomedical Applications of MXenes

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2D Metal Carbides and Nitrides (MXenes)

Abstract

The rapid pace of innovation in the fields of biomedicine and nanotechnology has generated a wide variety of novel nanomaterial-based platforms for biomedical applications. Based on the nanometer-thin two-dimensional planar morphology, the high effective surface area, the abundant surface chemistry, and the favorable physicochemical properties, there is a growing interest on exploring the potentials of MXenes at the interface with living systems. In this chapter, we review the state of the art and discuss the promise of MXenes for biomedical applications. Specifically, we first describe the properties of MXenes that make them particularly attractive and review the recent developments, with specific focus on the areas of biosensing, cancer theranostics, and antimicrobial treatments. Finally, we discuss the biocompatibility of MXenes based on the findings that have been reported so far.

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Author information

Authors and Affiliations

  1. Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA

    Flavia Vitale

  2. Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA

    Flavia Vitale, Nicolette Driscoll & Brendan Murphy

  3. Department of Physical Medicine & Rehabilitation, University of Pennsylvania, Philadelphia, PA, USA

    Flavia Vitale

  4. Center for Neurotrauma, Neurodegeneration, and Restoration, Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA

    Flavia Vitale, Nicolette Driscoll & Brendan Murphy

  5. Center for Neuroengineering and Therapeutics, University of Pennsylvania, Philadelphia, PA, USA

    Nicolette Driscoll & Brendan Murphy

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  1. Flavia Vitale
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  2. Nicolette Driscoll
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  3. Brendan Murphy
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Correspondence to Flavia Vitale .

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Editors and Affiliations

  1. Department of Mechanical and Energy Engineering, Purdue School of Engineering and Technology, Indiana University-Purdue University, Indianapolis (IUPUI), Indianapolis, IN, USA

    Babak Anasori

  2. Department of Materials Science and Engineering and A.J. Drexel Nanomaterials Institute, Drexel University, Philadelphia, PA, USA

    Yury Gogotsi

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Vitale, F., Driscoll, N., Murphy, B. (2019). Biomedical Applications of MXenes. In: Anasori, B., Gogotsi, Y. (eds) 2D Metal Carbides and Nitrides (MXenes). Springer, Cham. https://doi.org/10.1007/978-3-030-19026-2_26

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