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Clinical Cases in Psoriasis pp 71–78Cite as

The Non-compliant Psoriasis Patient

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Part of the book series: Clinical Cases in Dermatology ((CLIDADE))

Abstract

Patient compliance refers to the following of treatment instructions set forth by the clinician. Compliance may be maximized by choosing therapies with less frequent application, quicker onset of action, and fewer perceived side-effects. Psoriasis treatments with the highest compliance include biologics with longer dosing intervals, such as ustekinumab. Psoriasis treatments with the lowest compliance include topical therapies.

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References

  1. Richards HL, Fortune DG, O’Sullivan TM, Main CJ, Griffiths CE. Patients with psoriasis and their compliance with medication. J Am Acad Dermatol. 1999;41(4):581–3.

    CAS  PubMed  Google Scholar 

  2. Svendsen MT, Andersen F, Hansen J, Johannessen H, Andersen KE. Medical adherence to topical corticosteroid preparations prescribed for psoriasis: a systematic review. J Dermatolog Treat. 2017;28(1):32–9. https://doi.org/10.1080/09546634.2016.1178375.

    Article  CAS  PubMed  Google Scholar 

  3. Menter MA, Armstrong AW, Gordon KB, Wu JJ. Common and not-so-common comorbidities of psoriasis. Semin Cutan Med Surg. 2018;37(2S):S48–51. https://doi.org/10.12788/j.sder.2018.011.

    Article  PubMed  Google Scholar 

  4. Kurd SK, Troxel AB, Crits-Christoph P, Gelfand JM. The risk of depression, anxiety, and suicidality in patients with psoriasis: a population-based cohort study. Arch Dermatol. 2010;146(8):891–5. https://doi.org/10.1001/archdermatol.2010.186.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Rapp SR, Exum ML, Reboussin DM, Feldman SR, Fleischer A, Clark A. The physical, psychological and social impact of psoriasis. J Health Psychol. 1997;2(4):525–37. https://doi.org/10.1177/135910539700200409.

    Article  CAS  PubMed  Google Scholar 

  6. Langley RG, Feldman SR, Han C, Schenkel B, Szapary P, Hsu MC, et al. Ustekinumab significantly improves symptoms of anxiety, depression, and skin-related quality of life in patients with moderate-to-severe psoriasis: results from a randomized, double-blind, placebo-controlled phase III trial. J Am Acad Dermatol. 2010;63(3):457–65. https://doi.org/10.1016/j.jaad.2009.09.014.

    Article  CAS  PubMed  Google Scholar 

  7. Menter A, Augustin M, Signorovitch J, Yu AP, Wu EQ, Gupta SR, et al. The effect of adalimumab on reducing depression symptoms in patients with moderate to severe psoriasis: a randomized clinical trial. J Am Acad Dermatol. 2010;62(5):812–8. https://doi.org/10.1016/j.jaad.2009.07.022.

    Article  CAS  PubMed  Google Scholar 

  8. Mehta NN, Shin DB, Joshi AA, Dey AK, Armstrong AW, Duffin KC, et al. Effect of 2 psoriasis treatments on vascular inflammation and novel inflammatory cardiovascular biomarkers: a randomized placebo-controlled trial. Circ Cardiovasc Imaging. 2018;11(6):e007394. https://doi.org/10.1161/CIRCIMAGING.117.007394.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Wu JJ, Sundaram M, Cloutier M, Gauthier-Loiselle M, Guerin A, Singh R, Ganguli A. The risk of cardiovascular events in psoriasis patients treated with tumor necrosis factor-alpha inhibitors versus phototherapy: an observational cohort study. J Am Acad Dermatol. 2018;79(1):60–8. https://doi.org/10.1016/j.jaad.2018.02.050.

    Article  CAS  PubMed  Google Scholar 

  10. Choi CW, Kim BR, Ohn J, Youn SW. The advantage of cyclosporine a and methotrexate rotational therapy in long-term systemic treatment for chronic plaque psoriasis in a real world practice. Ann Dermatol. 2017;29(1):55–60. https://doi.org/10.5021/ad.2017.29.1.55.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Gokdemir G, Ari S, Koslu A. Adherence to treatment in patients with psoriasis vulgaris: Turkish experience. J Eur Acad Dermatol Venereol. 2008;22(3):330–5. https://doi.org/10.1111/j.1468-3083.2007.02425.x.

    Article  CAS  PubMed  Google Scholar 

  12. Zaghloul SS, Goodfield MJ. Objective assessment of compliance with psoriasis treatment. Arch Dermatol. 2004;140(4):408–14. https://doi.org/10.1001/archderm.140.4.408.

    Article  PubMed  Google Scholar 

  13. Zalewska A, Miniszewska J, Chodkiewicz J, Narbutt J. Acceptance of chronic illness in psoriasis vulgaris patients. J Eur Acad Dermatol Venereol. 2007;21(2):235–42. https://doi.org/10.1111/j.1468-3083.2006.01912.x.

    Article  CAS  PubMed  Google Scholar 

  14. Brown KK, Rehmus WE, Kimball AB. Determining the relative importance of patient motivations for nonadherence to topical corticosteroid therapy in psoriasis. J Am Acad Dermatol. 2006;55(4):607–13. https://doi.org/10.1016/j.jaad.2005.12.021.

    Article  PubMed  Google Scholar 

  15. Atkinson MJ, Sinha A, Hass SL, Colman SS, Kumar RN, Brod M, Rowland CR. Validation of a general measure of treatment satisfaction, the treatment satisfaction questionnaire for medication (TSQM), using a national panel study of chronic disease. Health Qual Life Outcomes. 2004;2:12. https://doi.org/10.1186/1477-7525-2-12.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Uhlenhake EE, Kurkowski D, Feldman SR. Conversations on psoriasis—what patients want and what physicians can provide: a qualitative look at patient and physician expectations. J Dermatolog Treat. 2010;21(1):6–12. https://doi.org/10.3109/09546630903085328.

    Article  PubMed  Google Scholar 

  17. Fouere S, Adjadj L, Pawin H. How patients experience psoriasis: results from a European survey. J Eur Acad Dermatol Venereol. 2005;19(Suppl 3):2–6. https://doi.org/10.1111/j.1468-3083.2005.01329.x.

    Article  PubMed  Google Scholar 

  18. Augustin M, Holland B, Dartsch D, Langenbruch A, Radtke MA. Adherence in the treatment of psoriasis: a systematic review. Dermatology. 2011;222(4):363–74. https://doi.org/10.1159/000329026.

    Article  CAS  PubMed  Google Scholar 

  19. Vangeli E, Bakhshi S, Baker A, Fisher A, Bucknor D, Mrowietz U, et al. A systematic review of factors associated with non-adherence to treatment for immune-mediated inflammatory diseases. Adv Ther. 2015;32(11):983–1028. https://doi.org/10.1007/s12325-015-0256-7.

    Article  PubMed  PubMed Central  Google Scholar 

  20. Clemmensen A, Spon M, Skov L, Zachariae C, Gniadecki R. Responses to ustekinumab in the anti-TNF agent-naive vs. anti-TNF agent-exposed patients with psoriasis vulgaris. J Eur Acad Dermatol Venereol. 2011;25(9):1037–40. https://doi.org/10.1111/j.1468-3083.2010.03914.x.

    Article  CAS  PubMed  Google Scholar 

  21. Umezawa Y, Nobeyama Y, Hayashi M, Fukuchi O, Ito T, Saeki H, Nakagawa H. Drug survival rates in patients with psoriasis after treatment with biologics. J Dermatol. 2013;40(12):1008–13. https://doi.org/10.1111/1346-8138.12353.

    Article  CAS  PubMed  Google Scholar 

  22. Esposito M, Gisondi P, Cassano N, Ferrucci G, Del Giglio M, Loconsole F, et al. Survival rate of antitumour necrosis factor-alpha treatments for psoriasis in routine dermatological practice: a multicentre observational study. Br J Dermatol. 2013;169(3):666–72. https://doi.org/10.1111/bjd.12422.

    Article  CAS  PubMed  Google Scholar 

  23. Gniadecki R, Kragballe K, Dam TN, Skov L. Comparison of drug survival rates for adalimumab, etanercept and infliximab in patients with psoriasis vulgaris. Br J Dermatol. 2011;164(5):1091–6. https://doi.org/10.1111/j.1365-2133.2011.10213.x.

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Frank H. Netter MD School of Medicine at Quinnipiac University, North Haven, CT, USA

    Kevin K. Wu

  2. Eastern Virginia Medical School, Norfolk, VA, USA

    Michael P. Lee

  3. Founder and CEO, Dermatology Research and Education Foundation, Irvine, CA, USA

    Jashin J. Wu

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  1. Kevin K. Wu
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  2. Michael P. Lee
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Editors and Affiliations

  1. Founder and CEO, Dermatology Research and Education Foundation, Irvine, CA, USA

    Jashin J. Wu

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Wu, K.K., Lee, M.P., Wu, J.J. (2019). The Non-compliant Psoriasis Patient. In: Wu, J. (eds) Clinical Cases in Psoriasis. Clinical Cases in Dermatology. Springer, Cham. https://doi.org/10.1007/978-3-030-18772-9_10

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  • DOI: https://doi.org/10.1007/978-3-030-18772-9_10

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-18771-2

  • Online ISBN: 978-3-030-18772-9

  • eBook Packages: MedicineMedicine (R0)

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