Driving Forces of Bioinformatics

  • Ramu ElangoEmail author
  • Babajan Banaganapalli
  • Noor Ahmad Shaik


Bioinformatics is driven by scientific development in a spectrum of fields, from biology, chemistry, physics, and statistics. Necessity is the mother of invention that fits nicely with the bioinformatics revolution. Scientific curiosity in different fields to understand the basic biology of living organisms dramatically changed our knowledge. Biology of the living organisms at the cell, tissue, and organ level required the combined efforts of scientists in different fields. Thousands of diseases of the world population put priority on understanding the normal functions of the different parts of the body at cellular, tissue, and organ level. Once the normal functions are known, then the question of addressing the management of the disease among the patient population can be addressed at different level from biology to drug discovery to better management and prevention. Bioinformatics joined the gold rush to understand the biology of living organisms at multilevel. One of the key drivers of this dramatic scientific development is the high-throughput data generation technologies in biology. Billions of data points from each sample or experiment drove bioinformatics scientists to play an important role in the biology.


Next-generation sequencing Microarray Single cell genomics Gene expression Variants Exome Genome wide association studies 


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Ramu Elango
    • 1
    Email author
  • Babajan Banaganapalli
    • 1
  • Noor Ahmad Shaik
    • 1
  1. 1.Princess Al-Jawhara Center of Excellence in Research of Hereditary DisordersDepartment of Genetic Medicine, Faculty of Medicine, King Abdulaziz UniversityJeddahSaudi Arabia

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