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Function vs. Taxonomy: The Case of Fungi Mitochondria ATP Synthase Genes

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Bioinformatics and Biomedical Engineering (IWBBIO 2019)

Part of the book series: Lecture Notes in Computer Science ((LNBI,volume 11465))

Abstract

We studied the relations between triplet composition of the family of mitochondrial atp6, atp8 and atp9 genes, their function, and taxonomy of the bearers. The points in 64-dimensional metric space corresponding to genes have been clustered. It was found the points are separated into three clusters corresponding to those genes. 223 mitochondrial genomes have been enrolled into the database.

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Notes

  1. 1.

    http://bioinfo-out.curie.fr/projects/vidaexpert/.

  2. 2.

    An advanced version of K-means yields the maximal number of distinguishable classes, see Sect. 3.

  3. 3.

    With respect to a minor deterioration by other genes.

References

  1. Molla, M., Delcher, A., Sunyaev, S., Cantor, C., Kasif, S.: Triplet repeat length bias and variation in the human transcriptome. Proc. Nat. Acad. Sci. 106(40), 17095–17100 (2009)

    Article  Google Scholar 

  2. Provata, A., Nicolis, C., Nicolis, G.: DNA viewed as an out-of-equilibrium structure. Phys. Rev. E 89, 052105 (2014)

    Article  Google Scholar 

  3. Qin, L., et al.: Survey and analysis of simple sequence repeats (SSRs) present in the genomes of plant viroids. FEBS Open Bio 4(1), 185–189 (2014)

    Article  Google Scholar 

  4. Moghaddasi, H., Khalifeh, K., Darooneh, A.H.: Distinguishing functional DNA words; a method for measuring clustering levels. Sci. Rep. 7, 41543 (2017)

    Article  Google Scholar 

  5. Bank, C., Hietpas, R.T., Jensen, J.D., Bolon, D.N.: A systematic survey of an intragenic epistatic landscape. Mol. Biol. Evol. 32(1), 229–238 (2015)

    Article  Google Scholar 

  6. Albrecht-Buehler, G.: Fractal genome sequences. Gene 498(1), 20–27 (2012)

    Article  Google Scholar 

  7. Sadovsky, M., Putintseva, Y., Chernyshova, A., Fedotova, V.: Genome structure of organelles strongly relates to taxonomy of bearers. In: Ortuño, F., Rojas, I. (eds.) IWBBIO 2015. LNCS, vol. 9043, pp. 481–490. Springer, Cham (2015). https://doi.org/10.1007/978-3-319-16483-0_47

    Chapter  Google Scholar 

  8. Sadovsky, M., Putintseva, Y., Birukov, V., Novikova, S., Krutovsky, K.: De Novo assembly and cluster analysis of Siberian Larch transcriptome and genome. In: Ortuño, F., Rojas, I. (eds.) IWBBIO 2016. LNCS, vol. 9656, pp. 455–464. Springer, Cham (2016). https://doi.org/10.1007/978-3-319-31744-1_41

    Chapter  Google Scholar 

  9. Sadovsky, M., Putintseva, Y., Zajtseva, N.: System biology of mitochondrion genomes. In: Qian, P.Y., Nghiem, S.V. (eds.) The Third International Conference on Bioinformatics, Biocomputational Systems and Biotechnologies, pp. 61–66, Venice/Mestre (2011)

    Google Scholar 

  10. Basse, C.W.: Mitochondrial inheritance in fungi. Curr. Opin. Microbiol. 13(6), 712–719 (2010)

    Article  Google Scholar 

  11. Gray, M.W., Burger, G., Lang, B.F.: Mitochondrial evolution. Science 283(5407), 1476–1481 (1999)

    Article  Google Scholar 

  12. Bullerwell, C.E., Lang, B.F.: Fungal evolution: the case of the vanishing mitochondrion. Curr. Opin. Microbiol. 8(4), 362–369 (2005)

    Article  Google Scholar 

  13. Esser, C., et al.: A genome phylogeny for mitochondria among \(\alpha \)-proteobacteria and a predominantly eubacterial ancestry of yeast nuclear genes. Mol. Biol. Evol. 21(9), 1643–1660 (2004)

    Article  Google Scholar 

  14. Davoodian, N., et al.: A global view of \(Gyroporus\): molecular phylogenetics, diversity patterns, and new species. Mycologia 110, 985–995 (2018)

    Article  Google Scholar 

  15. Nadimi, M., Daubois, L., Hijri, M.: Mitochondrial comparative genomics and phylogenetic signal assessment of mtDNA among arbuscular mycorrhizal fungi. Mol. Phylogenet. Evol. 98, 74–83 (2016)

    Article  Google Scholar 

  16. Fukunaga, K.: Introduction to Statistical Pattern Recognition. Academic Press, London (1990)

    MATH  Google Scholar 

  17. Gorban, A.N., Zinovyev, A.Y.: Fast and user-friendly non-linear principal manifold learning by method of elastic maps. In: 2015 IEEE International Conference on Data Science and Advanced Analytics, DSAA 2015, Campus des Cordeliers, Paris, France, 19–21 October 2015, pp. 1–9 (2015)

    Google Scholar 

  18. Gorban, A.N., Zinovyev, A.: Principal manifolds and graphs in practice: from molecular biology to dynamical systems. Int. J. Neural Syst. 20(03), 219–232 (2010). PMID: 20556849

    Article  Google Scholar 

  19. Gorban, A.N., Zinovyev, A.Y.: Principal manifolds for data visualisation and dimension reduction. In: Gorban, A.N., Ke̋gl, B., Wünsch, D., Zinovyev, A.Y. (eds.) LNCSE, vol. 58, 2nd edn, pp. 153–176. Springer, Berlin, Heidelberg, New York (2007). https://doi.org/10.1007/978-3-540-73750-6

    Chapter  Google Scholar 

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Acknowledgement

We are thankful to Reviewer whose remarks made the paper apparently better.

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Correspondence to Michael Sadovsky .

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Sadovsky, M., Fedotovskaya, V., Kolesnikova, A., Shpagina, T., Putintseva, Y. (2019). Function vs. Taxonomy: The Case of Fungi Mitochondria ATP Synthase Genes. In: Rojas, I., Valenzuela, O., Rojas, F., Ortuño, F. (eds) Bioinformatics and Biomedical Engineering. IWBBIO 2019. Lecture Notes in Computer Science(), vol 11465. Springer, Cham. https://doi.org/10.1007/978-3-030-17938-0_30

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  • DOI: https://doi.org/10.1007/978-3-030-17938-0_30

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