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International Work-Conference on Bioinformatics and Biomedical Engineering

IWBBIO 2019: Bioinformatics and Biomedical Engineering pp 75–86Cite as

Comparison of Numerical and Laboratory Experiment Examining Deformation of Red Blood Cell

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Part of the book series: Lecture Notes in Computer Science ((LNBI,volume 11466))

Abstract

In this work, we are dealing with a numerical model of red blood cell (RBC), which is compared to a real RBC. Our aim is to verify the accuracy of the model by comparing the behavior of simulated RBCs with behavior of the real cells in equivalent situations. For this comparison, we have chosen a microfluidic channel with narrow constrictions which was already explored in laboratory conditions with real RBCs. The relation between the cell deformation and its velocity is the element of comparison of simulated and real RBC. We conclude that the velocity-deformation dependence is similar in the two compared experiments.

This work was supported by the Slovak Research and Development Agency (contract number APVV-15-0751) and by the Ministry of Education, Science, Research and Sport of the Slovak Republic (contract No. VEGA 1/0643/17).

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References

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Authors and Affiliations

  1. Cell-in-Fluid Biomedical Modeling and Computations Group, Department of Software Technologies, Faculty of Management Science and Informatics, University of Zilina, Zilina, Slovakia

    Kristina Kovalcikova, Ivan Cimrak, Katarina Bachrata & Hynek Bachraty

Authors
  1. Kristina Kovalcikova
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  2. Ivan Cimrak
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  3. Katarina Bachrata
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  4. Hynek Bachraty
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Corresponding author

Correspondence to Kristina Kovalcikova .

Editor information

Editors and Affiliations

  1. Department of Computer Architecture and Computer Technology Higher Technical School of Information Technology and Telecommunications Engineering, CITIC-UGR, Granada, Spain

    Ignacio Rojas

  2. ETSIIT, University of Granada, Granada, Spain

    Olga Valenzuela

  3. CITIC-UGR, University of Granada, Granada, Spain

    Fernando Rojas

  4. Fundacion Progreso y Salud, Granada, Spain

    Francisco Ortuño

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Cite this paper

Kovalcikova, K., Cimrak, I., Bachrata, K., Bachraty, H. (2019). Comparison of Numerical and Laboratory Experiment Examining Deformation of Red Blood Cell. In: Rojas, I., Valenzuela, O., Rojas, F., Ortuño, F. (eds) Bioinformatics and Biomedical Engineering. IWBBIO 2019. Lecture Notes in Computer Science(), vol 11466. Springer, Cham. https://doi.org/10.1007/978-3-030-17935-9_8

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  • DOI: https://doi.org/10.1007/978-3-030-17935-9_8

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-17934-2

  • Online ISBN: 978-3-030-17935-9

  • eBook Packages: Computer ScienceComputer Science (R0)

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