Abstract
Gestational trophoblastic tumors are lesions derived from products of conception as opposed to tumors or lesions derived from the female gynecologic organs or patient’s tissue. These lesions can be divided into those that are non-neoplastic (villous) and those that are neoplastic proliferations; examples of the latter are choriocarcinoma, placental site trophoblastic tumor, and epithelioid trophoblastic tumor.
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References
Hui P, Martel M, Parkash V. Gestational trophoblastic diseases: recent advances in histopathologic diagnosis and related genetic aspects. Adv Anat Pathol. 2005;12:116–25.
Banet N, DeScipio C, Murphy KM, Beierl K, Adams E, Vang R, Ronnett BM. Characteristics of hydatidiform moles: analysis of a prospective series with p57 immunohistochemistry and molecular genotyping. Mod Pathol. 2014;27:238–54.
Gupta M, Vang R, Yemelyanova AV, Kurman RJ, Li FR, Maambo EC, et al. Diagnostic reproducibility of hydatidiform moles: ancillary techniques (p57 immunohistochemistry and molecular genotyping) improve morphologic diagnosis for both recently trained and experienced gynecologic pathologists. Am J Surg Pathol. 2012;36:1747–60.
Shih IM, Kurman RJ. Molecular basis of gestational trophoblastic diseases. Curr Mol Med. 2002;2:1–12.
Deavers MT, Kalhor N, Silva EG. Diagnostic problems with trophoblastic lesions. Arch Pathol Lab Med. 2008;132:168–74.
Banet N, Gown AM, Shih IM, Kay Li Q, Roden RB, Nucci MR, et al. GATA-3 expression in trophoblastic tissues: an immunohistochemical study of 445 cases, including diagnostic utility. Am J Surg Pathol. 2015;39:101–8.
Mirkovic J, Elias K, Drapkin R, Barletta JA, Quade B, Hirsch MS. GATA3 expression in gestational trophoblastic tissues and tumours. Histopathology. 2015;67:636–44.
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Fadare, O., Roma, A.A. (2019). Gestational Trophoblastic Tumors of the Uterus. In: Atlas of Uterine Pathology. Atlas of Anatomic Pathology. Springer, Cham. https://doi.org/10.1007/978-3-030-17931-1_6
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DOI: https://doi.org/10.1007/978-3-030-17931-1_6
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