Abstract
Coumarin derivatives have a known teratogenic effect but are relatively seldom used in early pregnancy nowadays. An association exists between maternal use of either anticoagulants or hemostatic drugs and a relatively severe malformation, notably a cardiovascular defect, in the offspring. This association is probably the result of a confounding by indication: a coagulopathy or a bleeding disorder.
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Källén, B. (2019). Maternal Use of Anticoagulants or Hemostatic Drugs and Infant Congenital Malformations. In: Maternal Drug Use and Infant Congenital Malformations. Springer, Cham. https://doi.org/10.1007/978-3-030-17898-7_8
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DOI: https://doi.org/10.1007/978-3-030-17898-7_8
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