Skip to main content

Fate of Veterinary Pharmaceuticals in Agroecosystems

  • Chapter
  • First Online:
Women in Water Quality

Part of the book series: Women in Engineering and Science ((WES))

Abstract

Veterinary pharmaceuticals, which are increasingly used in animal production practices, can enter surface and groundwater after land application of animal manures or animal wastewater. The presence of veterinary pharmaceuticals can result in negative environmental impacts including the proliferation of environmental antibiotic resistance and endocrine-disrupting effects in aquatic organisms. The efficacy of manure application strategies to limit the occurrence of veterinary pharmaceuticals in runoff and best management practices to remove these compounds from runoff prior to entering surface water should be investigated to mitigate the impact of these compounds on the environment.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 16.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 54.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Ali J, D’Souza D, Schwarz K, Allmon L, Singh RP, Snow DD, Bartelt-Hunt SL, Kolok A (2018) Endocrine effects following early life exposure to water and sediment found within agricultural runoff from the Elkhorn River, Nebraska, USA. Sci Total Environ 618:1371–1381

    Article  Google Scholar 

  2. Arikan OA, Mulbry W, Rice C (2009) Management of antibiotic residues from agricultural sources: use of composting to reduce chlortetracycline residues in beef manure from treated animals. J Hazard Mater 164:483–489

    Article  Google Scholar 

  3. Bao Y, Zhou W, Guan L, Wang Y (2009) Depletion of chlortetracycline during composting of ages and spiked manures. Waste Manag 29:1416–1423

    Article  Google Scholar 

  4. Bartelt-Hunt SL, Devivo S, Johnson L, Snow DD, Kranz WL, Mader TL, Shapiro CA, vanDonk SJ, Shelton DP, Tarkalson DD, Zhang TC (2013) Effect of composting on the fate of steroids in beef cattle manure. J Environ Qual 42:1159–1166

    Article  Google Scholar 

  5. Carlson JC, Mabury SA (2006) Dissipation kinetics and mobility of chlortetracycine, tylosin and monensin in an agricultural soil in Northumberland County, Ontario, Canada. Environ Toxicol Chem 25(1):10

    Article  Google Scholar 

  6. Davis JG, Truman CC, Kim SC, Ascough JC, Carlson K (2006) Antibiotic transport via runoff and soil loss. J Environ Qual 35(6):2250–2260

    Article  Google Scholar 

  7. Derby NE, Hakk H, Casey FXM, DeSutter TM (2011) Effects of composting swine manure on nutrients and estrogens. Soil Sci 176:91–98

    Article  Google Scholar 

  8. Dolliver H, Gupta S (2008) Antibiotic losses in leaching and surface runoff from manure-amended agricultural land. J Environ Qual 37(3):1227–1237

    Article  Google Scholar 

  9. Eghball B, Gilley JE, Kramer LA, Moorman TB (2000) Narrow grass hedge effects on phosphorus and nitrogen in runoff following manure and fertilizer application. J Water Soil Conserv 55:172–176

    Google Scholar 

  10. Eichhorn P, Aga DS (2004) Identification of a photooxygenation product of chlortetracycline in hog lagoons using LC/ESI-ion trap-MS and LC/ESI-time-of-flight-MS. Anal Chem 76(20):6002–6011

    Article  Google Scholar 

  11. Gilley JE, Eghball B, Marx DB (2008) Narrow grass hedge effects on nutrient transport following compost application. Trans ASABE 51:997–1005

    Article  Google Scholar 

  12. Gilley JE, Durso LM, Eigenberg RA, Marx DB, Woodbury BL (2011) Narrow grass hedge control of nutrient loads following variable manure applications. Trans ASABE 54:847–855

    Article  Google Scholar 

  13. Graham JP, Nachman KE (2010) Managing waste from confined animal feeding operations in the United States: the need for sanitary reform. J Water Health 8(4):646–670

    Article  Google Scholar 

  14. Heuer H, Schmitt H, Smalla K (2011) Antibiotic resistance gene spread due to manure application on agricultural fields. Curr Opin Microbiol 14(3):236–243

    Article  Google Scholar 

  15. Hu D, Coats JR (2007) Aerobic degradation and photolysis of tylosin in water and soil. Environ Toxicol Chem 26(5):884–889

    Article  Google Scholar 

  16. Jaimes-Correa JC, Snow DD, Bartelt-Hunt SL (2015) Seasonal occurrence of antibiotics and beta agonists in an agriculturally-intensive watershed. Environ Pollut 205:87–96

    Article  Google Scholar 

  17. Jjemba PK (2006) Excretion and ecotoxicity of pharmaceutical and personal care products in the environment. Ecotoxicol Environ Saf 63(1):113–130. https://doi.org/10.1016/j.ecoenv.2004.11.011

    Article  Google Scholar 

  18. Joy SR, Bartelt-Hunt SL, Snow DD, Gilley J, Woodbury B, Parker D, Marx D, Li X (2013) Fate and transport of antimicrobials and antimicrobial resistance genes in soil and runoff following land application of swine manure slurry. Environ Sci Technol 47(21):12081–12088

    Article  Google Scholar 

  19. Joy SR, Li X, Snow DD, Gilley JE, Woodbury B, Bartelt-Hunt SL (2014) Fate of antimicrobials and antimicrobial resistance genes in simulated swine manure storage. Sci Total Environ 481:69–74

    Article  Google Scholar 

  20. Kay P, Blackwell PA, Boxall ABA (2004) Fate of veterinary antibiotics in a macroporous tile drained clay soil. Environ Toxicol Chem 23(5):1136–1144

    Article  Google Scholar 

  21. Kim KR, Owens G, Ok YS, Park WK, Lee DB, Kwon SI (2012) Decline in extractable antibiotics in manure-based composts during composting. Waste Manag 32:110–116

    Article  Google Scholar 

  22. Kim S-C, Davis JG, Truman CC, Ascough JC II, Carlson K (2010) Simulated rainfall study for transport of veterinary antibiotics – mass balance analysis. J Hazard Mater 175(1–3):836–843

    Article  Google Scholar 

  23. Kolok AS, Sellin MK (2008) The environmental impact of growth-promoting compounds employed by the United States beef cattle industry: history, current knowledge and future directions. In: Whitacre DM (ed) Reviews of environmental contamination and toxicology

    Google Scholar 

  24. Kolz AC, Moorman TB, Ong SK, Scoggin KD, Douglass EA (2005) Degradation and metabolite production of tylosin in anaerobic and aerobic swine manure lagoons. Water Environ Res 44:49–56

    Article  Google Scholar 

  25. Kreuzig R, Holtge S, Brunotte J, Berenzen N, Wogram J, Schulz R (2005) Test-plot studies on runoff of sulfonamides from manured soils after sprinkler irrigation. Environ Toxicol Chem 24(4):777–781

    Article  Google Scholar 

  26. Landers TF, Cohen B, Wittum TE, Larson EL (2012) A review of antibiotic use in food animals: perspective, policy and potential. Public Health Rep 127:4–22

    Article  Google Scholar 

  27. Li L, Huang L, Chung R, Fok K, Zhang Y (2010) Sorption and dissipation of tetracyclines in soils and compost. Pedosphere 20:807–816

    Article  Google Scholar 

  28. Lin CH, Lerch RN, Goyne KW, Garrett HE (2011) Reducing herbicides and veterinary antibiotics losses from Agroecosystems using vegetative buffers. J Environ Qual 40:791–799

    Article  Google Scholar 

  29. Lissemore L, Hao C, Yang P, Sibley PK, Mabury S, Solomon KR (2006) An exposure assessment for selected pharmaceuticals within a watershed in Southern Ontario. Chemosphere 64(5):717–729

    Article  Google Scholar 

  30. Nawaz MS, Erickson BD, Khan AA, Khan SA, Pothuluri JV, Rafil F, Sutherland JB, Wagner RD, Cerniglia CE (2001) Human health impact and regulatory issues involving antimicrobial resistance in the food animal production environment. Regul Res Perspect 1(1):10

    Google Scholar 

  31. Owino JO, Owido SFO, Chemelil MC (2006) Nutrients in runoff from a clay loam soil protected by narrow grass strips. Soil Tillage Res 88:116–122

    Article  Google Scholar 

  32. Ramaswamy J, Prasher SO, Patel RM, Hussain SA, Barrington SF (2010) The effect of composting on the degradation of a veterinary pharmaceutical. Bioresour Technol 101:2294–2299

    Article  Google Scholar 

  33. Sangster JL, Ali JM, Snow DD, Kolok AS, Bartelt-Hunt SL (2016) Bioavailability and fate of sediment-associated progesterone in aquatic systems. Environ Sci Technol 50(7):4027–4036

    Article  Google Scholar 

  34. Sarmah AK, Meyer MT, Boxall ABA (2006) A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment. Chemosphere 65(5):725–759

    Article  Google Scholar 

  35. Sassman SA, Lee LS (2005) Sorption of three tetracyclines by several soils: assessing the role of pH and cation exchange. Environ Sci Technol 39(19):7452–7459

    Article  Google Scholar 

  36. Song W, Guo M (2014) Residual veterinary pharmaceuticals in animal manures and their environmental behavior in soils. In: He Z, Zhang H (eds) Applied manure and nutrient chemistry for sustainable agriculture and environment

    Google Scholar 

  37. Soni B, Bartelt-Hunt SL, Snow DD, Gilley J, Marx D, Woodbury B, Li X (2015) Effect of narrow grass hedges on the transport of antimicrobial and antimicrobial resistance genes in runoff following land application of swine slurry. J Environ Qual 44(3):895–902

    Article  Google Scholar 

  38. Stone JJ, Clay SA, Zhu Z, Wong KL, Porath LR, Spellman GM (2009) Effect of antimicrobial compounds tylosin and chlortetracycline during batch anaerobic swine manure digestion. Water Res 43:4740–4750

    Article  Google Scholar 

  39. Szogi AA, Vanotti MB, Ro KS (2015) Methods for treatment of animal manures to reduce nutrient pollution prior to soil application. Curr Pollut Rep 1(1):47–56

    Article  Google Scholar 

  40. Werner JJ, McNeill K, Arnold WA (2009) Photolysis of chlortetracycline on a clay surface. J Agric Food Chem 57(15):6932–6937

    Article  Google Scholar 

  41. Zhang Y, Krysl RG, Ali JM, Snow DD, Bartelt-Hunt SL, Kolok AS (2015) Impact of sediment on agrichemical fate and bioavailability to adult female fathead minnows: a field study. Environ Sci Technol 49(15):9037–9047

    Article  Google Scholar 

Download references

Acknowledgments

I would like to acknowledge my collaborators in the work presented in this chapter including Dr. Xu Li, Dr. Daniel Snow of the University of Nebraska-Lincoln, and Dr. John Gilley of the United States Department of Agriculture. I would also like to thank the many students who worked on these projects including Juan Jaimes Correa, Stacey (Joy) Thomas, and Bhavneet Soni.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Shannon L. Bartelt-Hunt .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Bartelt-Hunt, S.L. (2020). Fate of Veterinary Pharmaceuticals in Agroecosystems. In: O’Bannon, D. (eds) Women in Water Quality. Women in Engineering and Science. Springer, Cham. https://doi.org/10.1007/978-3-030-17819-2_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-17819-2_10

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-17818-5

  • Online ISBN: 978-3-030-17819-2

  • eBook Packages: EngineeringEngineering (R0)

Publish with us

Policies and ethics