Abstract
Central nervous system (CNS) tumor has a high incidence during childhood and represents the second most common neoplasm in the pediatric population, only behind leukemias that are the most frequent tumors in children under 15 years old. The most frequent CNS tumors in the pediatric population are midline neoplasms (pontine and hypothalamic gliomas and craniopharyngiomas), posterior fossa tumors, and embrionary tumors. Approximately, 50–60% of these tumors have their initial growth in the posterior fossa. Many of the signs and symptoms are present in common pathologies like gastroenteritis, migraine, and behavioral disorders and can cause misdiagnoses. We describe the most common pediatric tumors and their treatment and prognosis.
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Karajannis M, Allen JC, Newcomb EW. Treatment of pediatric brain tumors. J Cell Physiol. 2008;217(3):584–9.
Sala F, Cloarusso E, Mazza C, et al. Brain tumors in children under 3 years of age. Recent experience (1987–1997) in 39 patients. Pediatr Neurosurg. 1999;31:16–26.
Wilne S, Collier J, Kennedy C, Koller K, Grundy R, Walker D. Presentation of childhood CNS tumours: a systematic review and meta-analysis. Lancet Oncol. 2007;8:685–95.
Gajjar A, Chintagumpala M, Ashley D, et al. Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial. Lancet Oncol. 2006;7:813–20.
Dhall G, Grodman H, Ji L, et al. Outcome of children less than three years old at diagnosis with non-metastatic medulloblastoma treated with chemotherapy on the “Head Start” I and II protocols. Pediatr Blood Cancer. 2008;50:1169–75.
Keating R, Goodrich J, Packer R. Tumors of the pediatric central nervous system. New York/Stuttgart: Thieme; 2001.
Pollack IF, Jakacki R, Deutsch M, Hamilton RL. Current management of pediatric brain tumors. Semin Neurosurg. 2002;1:13.
Kaplan A, Albright A, Zimmerman R, et al. Brainstem gliomas in children. A Children’s Cancer Group review of 119 cases. Pediatr Neurosurg. 1996;24:185–92.
Joaquim AF, Ghizoni E, Tedeschi H, Oliveira E. Ependimomas. In: Sebastião Eurico de Melo Souza (Org.). Tratamento das Doenças Neurológicas, vol. 1. 3ª ed. Rio de Janeiro: Guanabara Koogan; 2013. p. 368–71.
Echevarría ME, Fangusaro J, Goldman S. Pediatric central nervous system germ cell tumors: a review. Oncologist. 2008;13:690–9.
Ghizoni E, Joaquim AF, Tedeschi H, Oliveira E. Tumores da Região Pineal. In: Sebastião Eurico de Melo Souza (Org.). Tratamento das Doenças Neurológicas, vol. 1. 3ª ed. Rio de Janeiro: Guanabara Koogan; 2013. p. 329–33.
Ghizoni E, Joaquim AF, Tedeschi H, Oliveira E. Craniofaringiomas. In: Sebastião Eurico de Melo Souza (Org.). Tratamento das Doenças Neurológicas, vol. 1. 3ª ed. Rio de Janeiro: Guanabara Koogan; 2013. p. 339–41.
Kassam A, Thomas AJ, Snyderman C, et al. Fully endoscopic expanded endonasal approach treating skull base lesions in pediatric patients. J Neurosurg Pediatr. 2007;106(2):75–86. https://doi.org/10.3171/ped.2007.106.2.75.assam:2007.
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Ghizoni, E., Naccarato, C.R.M., Mathias, R.N. (2019). Brain Tumors in Children. In: Joaquim, A., Ghizoni, E., Tedeschi, H., Ferreira, M. (eds) Fundamentals of Neurosurgery. Springer, Cham. https://doi.org/10.1007/978-3-030-17649-5_18
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DOI: https://doi.org/10.1007/978-3-030-17649-5_18
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