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Parathyroid PET

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Radionuclide Parathyroid Imaging

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Abstract

Positron emission tomography (PET) is a radionuclide imaging modality which is inherently tomographic in nature with several advantages over conventional single-photon scintigraphy, primarily higher spatial resolution and is usually performed using hybrid (positron emission tomography/computed tomography, PET/CT) approach. The first radiopharmaceutical used for parathyroid imaging, positron-emitting 75Se-selenomethionine, was replaced by single-photon tracers due to poor imaging characteristic. Of the several PET radiopharmaceuticals investigated for parathyroid imaging, only 11C-methionine has been more extensively studied. It was found to be more sensitive than the conventional imaging modalities, but its use is limited due to poor availability. Recently, the more widely available PET tracers, 11C-choline and particularly 18F-fluorocholine, have been introduced for parathyroid imaging, demonstrating very good imaging characteristics, very high sensitivity and superior diagnostic performance over conventional parathyroid imaging modalities.

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Authors and Affiliations

  1. Department of Nuclear Medicine, University Medical Centre Ljubljana, Ljubljana, Slovenia

    Luka Lezaic & Marko Grmek

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  1. Luka Lezaic
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  2. Marko Grmek
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Correspondence to Luka Lezaic .

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Editors and Affiliations

  1. Department of Nuclear Medicine, Farwaniya Hospital, Kuwait, Kuwait

    Qaisar Hussain Siraj

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Lezaic, L., Grmek, M. (2019). Parathyroid PET. In: Siraj, Q. (eds) Radionuclide Parathyroid Imaging. Springer, Cham. https://doi.org/10.1007/978-3-030-17351-7_6

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  • DOI: https://doi.org/10.1007/978-3-030-17351-7_6

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-17350-0

  • Online ISBN: 978-3-030-17351-7

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