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Fabrication of Biodegradable Mg Alloy Bone Scaffold Through Electrical Discharge µ-Drilling Route

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Advances in Manufacturing II (MANUFACTURING 2019)

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Abstract

Magnesium alloys based materials are gaining popularity for bone tissue engineering as they are biocompatible, bioresorbable and shows high osteoblast activities in biological environment. In present work, perforated structures are produced using electrical discharge drilling (EDD), with an attempt to fabricate Mg alloy based biodegradable scaffold for bone tissue engineering. Using appropriate EDD parameters and tubular electrode of diameter 300 µm, micro holes of diameter 408 µm are produced in ZM21 alloy and two different types of perforated structures are obtained with porosity of 22% and 34%. These two perforated structures are compared with solid sample in terms of apatite formation, weight gain and loss of load bearing capacity after immersion in simulated body fluid (SBF) media. After 21 days of immersion test in SBF media, apatite formation in perforated structure with interconnected holes (porosity 34%) is highest, resulting into highest weight gain of 6.23%, for this sample, whereas, solid sample shows negligible weight gain of 0.58%. The loss in mechanical load bearing capacity is found lowest at 5.58% in scaffold having interconnected holes (with porosity 34%). Thus, interconnected perforated Mg alloy structures having well defined micro pores and pore density can be designed and fabricated for biodegradable scaffold application.

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Acknowledgement

The funding for this work is sponsored by Science & Engineering Research Board, Department of Science and Technology, New Delhi, India under the research project entitled “Design and Development of biodegradable Mg alloy Implants for orthopedic application” (File Number: EMR/2016/001581).

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Authors and Affiliations

  1. Department of Materials and Metallurgical Engineering, Punjab Engineering College, Chandigarh, 160012, India

    Neeraj Ahuja & Uma Batra

  2. Department of Mechanical Engineering, Punjab Engineering College, Chandigarh, 160012, India

    Kamal Kumar

  3. Department of Orthopedics, Government Medical College and Hospital, Sector-32, Chandigarh, 160030, India

    Sudhir Kumar Garg

Authors
  1. Neeraj Ahuja
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  2. Kamal Kumar
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  3. Uma Batra
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  4. Sudhir Kumar Garg
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Corresponding author

Correspondence to Kamal Kumar .

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Editors and Affiliations

  1. Institute of Mechanical Technology, Division of Metrology and Measurement Systems, Poznan University of Technology, Poznan, Poland

    Bartosz Gapiński

  2. Institute of Material’s Technology, Division of Polymer Processing, Poznan University of Technology, Poznan, Poland

    Marek Szostak

  3. Department of Manufacturing Engineering, Machines and Tools, Sumy State University, Sumy, Ukraine

    Vitalii Ivanov

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Ahuja, N., Kumar, K., Batra, U., Garg, S.K. (2019). Fabrication of Biodegradable Mg Alloy Bone Scaffold Through Electrical Discharge µ-Drilling Route. In: Gapiński, B., Szostak, M., Ivanov, V. (eds) Advances in Manufacturing II. MANUFACTURING 2019. Lecture Notes in Mechanical Engineering. Springer, Cham. https://doi.org/10.1007/978-3-030-16943-5_13

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  • DOI: https://doi.org/10.1007/978-3-030-16943-5_13

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  • Online ISBN: 978-3-030-16943-5

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