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Nutritional Support After Surgery of the Liver

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Nutritional Support after Gastrointestinal Surgery

Abstract

Liver resection remains the only curative treatment for hepatic malignancies. Many progresses have been recently done in the field of chemotherapy that, in association with surgery, could guarantee the best survival for patients with liver malignancies including primitive cancer (hepatocellular carcinoma, cholangiocarcinoma) and metastatic cancer (colorectal liver metastasis, breast cancer). The main concept of resectability in liver surgery is associated to the concept of leaving a sufficient quote of liver parenchyma to guarantee a sufficient liver function which is mandatory to reduce the risk of postoperative liver failure. Recently, several improvements in the perioperative management of surgical patient have been introduced. For example, prediction of future remnant liver could be calculated with 3D reconstruction software, as well as quality of liver function with the ICG test. Minimally invasive surgery (robotic and laparoscopic) has also contributed to minimize the surgical trauma. Furthermore, adhesion to the ERAS (enhanced recovery after surgery) protocols has contributed to reduce postoperative in hospital stay.

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References

  1. Rahnemai-Azar AA, Cloyd JM, Weber SM, Dillhoff M, Schmidt C, Winslow ER, et al. Update on liver failure following hepatic resection: strategies for prediction and avoidance of post-operative liver insufficiency. J Clin Transl Hepatol. 2018;6(1):1–8.

    Article  Google Scholar 

  2. Chan J, Perini M, Fink M, Nikfarjam M. The outcomes of central hepatectomy versus extended hepatectomy: a systematic review and meta-analysis. HPB (Oxford). 2018;20:487–96.

    Article  Google Scholar 

  3. Cieslak KP, Huisman F, Bais T, Bennink RJ, van Lienden KP, Verheij J, et al. Future remnant liver function as predictive factor for the hypertrophy response after portal vein embolization. Surgery. 2017;162(1):37–47.

    Article  Google Scholar 

  4. de Baere T, Teriitehau C, Deschamps F, Catherine L, Rao P, Hakime A, et al. Predictive factors for hypertrophy of the future remnant liver after selective portal vein embolization. Ann Surg Oncol. 2010;17(8):2081–9.

    Article  Google Scholar 

  5. Rhaiem R, Piardi T, Chetboun M, Pessaux P, Lestra T, Memeo R, et al. Portal inflow modulation by somatostatin after major liver resection. Ann Surg. 2018;267:e101–3. http://www.ncbi.nlm.nih.gov/pubmed/29189385

    Article  Google Scholar 

  6. Okajima C, Arii S, Tanaka S, Matsumura S, Ban D, Ochiai T, et al. Prognostic role of child-Pugh score 5 and 6 in hepatocellular carcinoma patients who underwent curative hepatic resection. Am J Surg. 2015;209(1):199–205.

    Article  Google Scholar 

  7. Wakabayashi G, Cherqui D, Geller DA, Buell JF, Kaneko H, Han HS, et al. Recommendations for laparoscopic liver resection: a report from the second international consensus conference held in Morioka. Ann Surg. 2015;261(4):619–29.

    PubMed  Google Scholar 

  8. Giulianotti PC, Bianco FM, Daskalaki D, Gonzalez-Ciccarelli LF, Kim J, Benedetti E. Robotic liver surgery: technical aspects and review of the literature. Hepatobil Surg Nutr. 2016;5(4):311–21.

    Article  Google Scholar 

  9. Cieslak KP, Runge JH, Heger M, Stoker J, Bennink RJ, van Gulik TM. New perspectives in the assessment of future remnant liver. Dig Surg. 2014;31(4–5):255–68.

    Article  Google Scholar 

  10. Memeo R, De Blasi V, Adam R, Goéré D, Azoulay D, Ayav A, et al. Parenchymal-sparing hepatectomies (PSH) for bilobar colorectal liver metastases are associated with a lower morbidity and similar oncological results: a propensity score matching analysis. HPB (Oxford). 2016;18:781–90.

    Article  Google Scholar 

  11. Pauli EM, Staveley-O’Carroll KF, Brock MV, Efron DT, Efron G. A handy tool to teach segmental liver anatomy to surgical trainees. Arch Surg. 2012;147(8):692–3.

    Article  Google Scholar 

  12. Memeo R, De’Angelis N, Compagnon P, Salloum C, Cherqui D, Laurent A, et al. Laparoscopic vs. open liver resection for hepatocellular carcinoma of cirrhotic liver: a case-control study. World J Surg. 2014;38(11):2919–26.

    Article  Google Scholar 

  13. Huang X, Lu S. A meta-analysis comparing the effect of anatomical resection vs. non-anatomical resection on the long-term outcomes for patients undergoing hepatic resection for hepatocellular carcinoma. HPB (Oxford). 2017;19(10):843–9.

    Article  Google Scholar 

  14. Appéré F, Piardi T, Memeo R, Lardière-Deguelte S, Chetboun M, Sommacale D, et al. Comparative study with propensity score matching analysis of two different methods of transection during hemi-right hepatectomy: ultracision harmonic scalpel versus cavitron ultrasonic surgical aspirator. Surg Innov. 2017;24(5):499–508.

    Article  Google Scholar 

  15. Sotiropoulos GC, Prodromidou A, Kostakis ID, Machairas N. Meta-analysis of laparoscopic vs open liver resection for hepatocellular carcinoma. Updat Surg. 2018;9(3):291–311.

    Google Scholar 

  16. Nagasue N, et al. Human liver regeneration after major hepatic resection. A study of normal liver and liver with chronic hepatitis and cirrhosis. Ann Surg. 1987;206:30–9.

    Article  CAS  Google Scholar 

  17. Michalopoulos GK, De Frences MC. Liver regeneration. Science. 1997;276:60.

    Article  CAS  Google Scholar 

  18. Harimoto N, Hoshino H, Muranushi R, Hagiwara K, Yamanaka T, Tsukagoshi M, Igarashi T, Watanabe A, Kubo N, Araki K, Shirabe K. Skeletal muscle volume and intramuscular adipose tissue are prognostic predictors of postoperative complications after hepatic resection. Anticancer Res. 2018;38(8):4933–9.

    Article  Google Scholar 

  19. Arias JM, et al., editors. The liver: biology and pathology. 3rd ed. New York: Raven Press; 1994.

    Google Scholar 

  20. Tajiri K, et al. Liver physiology and liver diseases in the elderly. World J Gastroenterol. 2013;19:8459–67.

    Article  Google Scholar 

  21. Newberne P, Corner MW. Food additives and contaminants: an update. Cancer. 1986;58:1851–62.

    Article  CAS  Google Scholar 

  22. Guzzon R, et al. Evaluation of the oenological suitability of grapes grown using biodynamic agriculture: the case of a bad vintage. J Appl Microbiol. 2016;120:355–65.

    Article  CAS  Google Scholar 

  23. Oates L, Cohen M, Braun L, Schembri A, Taskova R. Reduction in urinary organophosphate pesticide metabolites in adults after a week-long organic diet. Environ Res. 2014;132:105–11.

    Article  CAS  Google Scholar 

  24. Göen T, Schmidt L, Lichtensteiger W, Schlumpf M. Efficiency control of dietary pesticide intake reduction by human biomonitoring. Int J Hyg Environ Health. 2017;220(2 Pt A):254–60.

    Article  Google Scholar 

  25. Okuno M, Goudmard C, Kopetz S, Vega EA, Joechle K, Mizuno T, Tzeng CD, Chun YS, Lee JE, Vauthey JN, Aloia TA, Conrad C. Loss of muscle mass during preoperative chemotherapy as a prognosticator for poor survival in patients with colorectal liver metastases. Surgery. 2019;165:329–36.

    Article  Google Scholar 

  26. Baudry J, Méjean C, Allès B, Péneau S, Touvier M, Hercberg S, Lairon D, Galan P, Kesse-Guyot E. Contribution of organic food to the diet in a large sample of French adults (the NutriNet-Santé Cohort Study). Nutrients. 2015;7(10):8615–32.

    Article  Google Scholar 

  27. Zhou Y, Li Y, Zhou T, Zheng J, Li S, Li HB. Dietary natural products for prevention and treatment of liver cancer. Nutrients. 2016;8(3):156.

    Article  Google Scholar 

  28. Goetzke B, Nitzko S, Spiller A. Consumption of organic and functional food. A matter of well-being and health? Appetite. 2014;77:94–103.

    Article  Google Scholar 

  29. Kim JY, Kwon O. Culinary plants and their potential impact on metabolic overload. Ann N Y Acad Sci. 2011;1229:133–9.

    Article  CAS  Google Scholar 

  30. Tiwari AK. Revisiting “vegetables” to combat modern epidemic of imbalanced glucose homeostasis. Pharmacogn Mag. 2014;10(Suppl 2):S207–13.

    Article  Google Scholar 

  31. Sung B, Prasad S, Yadav VR, Aggarwal BB. Cancer cell signalling pathways targeted by spice-derived nutraceuticals. Nutr Cancer. 2012;64(2):173–97.

    Article  CAS  Google Scholar 

  32. Kannappan R, Gupta SC, Kim JH, Reuter S, Aggarwal BB. Neuroprotection by spice-derived nutraceuticals: you are what you eat! Mol Neurobiol. 2011;44(2):142–59.

    Article  CAS  Google Scholar 

  33. Tapsell LC, Hemphill I, Cobiac L, Patch CS, Sullivan DR, Fenech M, Roodenrys S, Keogh JB, Clifton PM, Williams PG, Fazio VA, Inge KE. Health benefits of herbs and spices: the past, the present, the future. Med J Aust. 2006;185(4 Suppl):S4–24.

    PubMed  Google Scholar 

  34. Brenner DA, Paik YH, Schnabl B. Role of gut microbiota in liver disease. J Clin Gastroenterol. 2015;49(Suppl 1):S25–7.

    Article  CAS  Google Scholar 

  35. de Faria Ghetti F, Oliveira DG, de Oliveira JM, de Castro Ferreira LEVV, Cesar DE, Moreira APB. Influence of gut microbiota on the development and progression of nonalcoholic steatohepatitis. Eur J Nutr. 2018;57(3):861–76. https://doi.org/10.1007/s00394-017-1524-x.

    Article  CAS  PubMed  Google Scholar 

  36. Acharya C, Bajaj JS. Gut microbiota and complications of liver disease. Gastroenterol Clin N Am. 2017;46(1):155–69. https://doi.org/10.1016/j.gtc.2016.09.013.

    Article  Google Scholar 

  37. Jamnik J, Rehman S, Mejia SB, de Souza RJ, Khan TA, Leiter LA, Wolever TMS, Kendall CWC, Jenkins DJA, Sievenpiper JL. Fructose intake and risk of gout and hyperuricemia: a systematic review and meta-analysis of prospective cohort studies. BMJ Open. 2016;6(10):e013191. https://doi.org/10.1136/bmjopen-2016-013191.

    Article  PubMed  PubMed Central  Google Scholar 

  38. ter Horst KW, Serlie MJ, et al. Fructose consumption, lipogenesis, and non-alcoholic fatty liver disease. Nutrients. 2017;9:981.

    Article  Google Scholar 

  39. Tanaka S, Iimuro Y, Hirano T, Hai S, Suzumura K, Nakamura I, Kondo Y, Fujimoto J. Safety of hepatic resection for hepatocellular carcinoma in obese patients with cirrhosis. Surg Today. 2013;43(11):1290–7. https://doi.org/10.1007/s00595-013-0706-2.

    Article  CAS  PubMed  Google Scholar 

  40. Grąt M, Wronka KM, Krasnodębski M, Masior Ł, Lewandowski Z, Kosińska I, Grąt K, Stypułkowski J, Rejowski S, Wasilewicz M, Gałęcka M, Szachta P, Krawczyk M. Profile of gut microbiota associated with the presence of hepatocellular cancer in patients with liver cirrhosis. Transplant Proc. 2016;48(5):1687–91. https://doi.org/10.1016/j.transproceed.2016.01.077.

    Article  PubMed  Google Scholar 

  41. Amodio P, Bemeur C, Butterworth R, Cordoba J, Kato A, Montagnese S, Uribe M, Vilstrup H, Morgan MY. The nutritional management of hepatic encephalopathy in patients with cirrhosis: International Society for Hepatic Encephalopathy and Nitrogen Metabolism Consensus. Hepatology. 2013;58(1):325–36. https://doi.org/10.1002/hep.26370.

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Riccardo Memeo .

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Memeo, R., D’Eugenio, A. (2019). Nutritional Support After Surgery of the Liver. In: Altomare, D., Rotelli, M. (eds) Nutritional Support after Gastrointestinal Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-16554-3_8

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  • DOI: https://doi.org/10.1007/978-3-030-16554-3_8

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