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Regulation of Food Intake After Surgery and the Gut-Brain Axis

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Nutritional Support after Gastrointestinal Surgery

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Abstract

The metabolic and physiological changes associated with surgery are well established. There is a transient physiological state of impaired glucose tolerance (known as insulin resistance) along with the release of stress hormones and inflammatory mediators (cytokines, cortisol, catecholamines, glucagon) [1–3]. This results in attenuation of the anabolic effects of insulin, impairment of glucose uptake in peripheral tissues (e.g. skeletal muscle and adipose tissue) and enhancement of hepatic gluconeogenesis resulting in hyperglycaemia [4].

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Author information

Authors and Affiliations

  1. Upper Gastrointestinal and General Surgery, University Hospitals Coventry and Warwickshire, Coventry, UK

    Nilanjana Tewari

  2. Gastrointestinal Surgery, Nottingham Digestive Diseases Centre, National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Queen’s Medical Centre, Nottingham, UK

    Nilanjana Tewari & Dileep N. Lobo

  3. MRC/ARUK Centre for Musculoskeletal Ageing Research, University of Nottingham, Queen’s Medical Centre, Nottingham, UK

    Dileep N. Lobo

Authors
  1. Nilanjana Tewari
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  2. Dileep N. Lobo
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Correspondence to Dileep N. Lobo .

Editor information

Editors and Affiliations

  1. Department of Emergency and Organ Transplant, University of Bari Aldo Moro, Bari, Italy

    Donato Francesco Altomare

  2. Department of Emergency and Organ Transplant, University of Bari Aldo Moro, Bari, Italy

    Maria Teresa Rotelli

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Tewari, N., Lobo, D.N. (2019). Regulation of Food Intake After Surgery and the Gut-Brain Axis. In: Altomare, D., Rotelli, M. (eds) Nutritional Support after Gastrointestinal Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-16554-3_1

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  • DOI: https://doi.org/10.1007/978-3-030-16554-3_1

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  • Online ISBN: 978-3-030-16554-3

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