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Cancer Bionanotechnology: Biogenic Synthesis of Metallic Nanoparticles and Their Pharmaceutical Potency

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Book cover Microbial Nanobionics

Part of the book series: Nanotechnology in the Life Sciences ((NALIS))

Abstract

Nanotechnology is an emerging field of science that promises to revolutionize medicine in the twenty-first century, as it offers great potential to radically advance the diagnosis, prevention, and treatment of diseases such as cancer. Nanoparticles can be synthesized using chemical, physical, and biological synthesis methods. However, chemical and physical synthesis methods have shown to pose threats to the ecosystem, while the biological synthesis route as a green synthesis method has proven to be a nontoxic and eco-friendly method for generation of green nanoparticles with great potential to improve anticancer properties. This chapter will provide comprehensive detail on biogenic synthesis of silver and gold nanoparticles using bacteria, fungi, and yeast through intracellular and extracellular routes. This chapter will also demonstrate the potential benefits and the mechanism of toxicity of nanoparticles on cancer cells as a potential anticancer agent. Furthermore, the chapter will look at the setbacks and future prospects of biological production of silver and gold nanoparticles with industrial production suitability.

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Authors and Affiliations

  1. Nanotechnology and Biotechnology, Nabio Consulting, Pretoria, South Africa

    Maluta Steven Mufamadi & Jiya George

  2. Knowledge Economy and Scientific Advancement, Mapungubwe Institute for Strategic Reflection (MISTRA), Johannesburg, South Africa

    Zamanzima Mazibuko

  3. Department of Plant and Soil Sciences, University of Pretoria, Pretoria, South Africa

    Thilivhali Emmanuel Tshikalange

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  1. Maluta Steven Mufamadi
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  3. Zamanzima Mazibuko
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  4. Thilivhali Emmanuel Tshikalange
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Correspondence to Maluta Steven Mufamadi .

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  1. Department of Botany, Mahatma Gandhi Central University, Motihari, Bihar, India

    Ram Prasad

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Mufamadi, M.S., George, J., Mazibuko, Z., Tshikalange, T.E. (2019). Cancer Bionanotechnology: Biogenic Synthesis of Metallic Nanoparticles and Their Pharmaceutical Potency. In: Prasad, R. (eds) Microbial Nanobionics. Nanotechnology in the Life Sciences. Springer, Cham. https://doi.org/10.1007/978-3-030-16383-9_10

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