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Enhancing Treatment Access and Effectiveness: Toward Patient-Centered Models of Care

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Part of the book series: Current Clinical Psychiatry ((CCPSY))

Abstract

In the United States, despite the availability of safe and effective pharmacotherapy and behavioral treatments for opioid use disorder (OUD), a minority of people who need treatment receive it. Improving treatment uptake will require OUD treatments that are available, accessible, and acceptable to people with OUD. The objectives of this chapter are (1) to describe barriers to OUD treatment; (2) to present patient preferences for OUD treatment; (3) to recommend modifications to current OUD treatment models in the United States that would make treatment more available, accessible, and acceptable to people with OUD; and (4) to present a patient-centered model of OUD care that focuses on engagement, retention in care, and harm reduction while serving both people who want to stop illicit opioid use and those who do not. Though many people with OUD enter stable recovery without using formal treatment, many barriers to care do exist for people who want and could benefit from evidence-based OUD treatments. Societal change will be needed to reduce stigma regarding OUD and agonist treatments. Policy change will be needed to make the full spectrum of OUD treatments more available and affordable in every community. Modifying OUD treatment models to be more patient-centered could also increase treatment uptake by improving acceptability and desirability of treatment. There will be no easy way to stem the increasing harms from the opioid epidemic, but bringing people into care is an important first step.

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Abbreviations

HCV:

Hepatitis C virus (HCV)

HIV:

Human immunodeficiency virus

LGBTQ:

Lesbian, gay, bisexual, transgender, queer

MMT:

Methadone maintenance treatment

NSDUH:

National Survey on Drug Use and Health

OTP:

Opioid treatment program

OUD:

Opioid use disorder

SUD:

Substance use disorder

US:

United States

References

  1. Romo E, Ulbricht CM, Clark RE, Lapane KL. Correlates of specialty substance use treatment among adults with opioid use disorders. Addict Behav. 2018;86:96–103.

    Article  PubMed  Google Scholar 

  2. Rudd RA, Seth P, David F, Scholl L. Increases in drug and opioid-involved overdose deaths – United States, 2010–2015. MMWR Morb Mortal Wkly Rep. 2016;65(5051):1445–52.

    Article  PubMed  Google Scholar 

  3. Hedegaard H, Warner M, Miniño AM. Drug overdose deaths in the United States, 1999–2016. NCHS Data Brief, no 294. Hyattsville, MD: National Center for Health Statistics; 2017.

    Google Scholar 

  4. Saloner B, Karthikeyan S. Changes in substance abuse treatment use among individuals with opioid use disorders in the United States, 2004–2013. JAMA. 2015;314(14):1515–7.

    Article  PubMed  Google Scholar 

  5. Morgan JR, Schackman BR, Leff JA, Linas BP, Walley AY. Injectable naltrexone, oral naltrexone, and buprenorphine utilization and discontinuation among individuals treated for opioid use disorder in a United States commercially insured population. J Subst Abus Treat. 2018;85:90–6.

    Article  Google Scholar 

  6. Center for Behavioral Health Statistics and Quality. Key substance use and mental health indicators in the United States: results from the 2015 National Survey on Drug Use and Health. HHS Publication No. SMA 16-4984, NSDUH Series H-51. Rockville: Substance Abuse and Mental Health Services Administration; 2016. [cited 2018 Aug 26]. Available at: http://www.samhsa.gov/data on August 26, 2018.

    Google Scholar 

  7. Han B, Compton WM, Blanco C, Crane E, Lee J, Jones CM. Prescription opioid use, misuse, and use disorders in U.S. adults: 2015 national survey on drug use and health. Ann Intern Med. 2017;167(5):293–301.

    Article  PubMed  Google Scholar 

  8. Casteel K. Data on drug use is disappearing just when we need it most. 29 Jun 2017 [cited August 23, 2018]. In: FiveThirtyEight [Internet]. Available from: https://fivethirtyeight.com/features/data-on-drug-use-is-disappearing-just-when-we-need-it-most/.

  9. Dwyer-Lindgren L, Bertozzi-Villa A, Stubbs RW, Morozoff C, Shirude S, Unutzer J, et al. Trends and patterns of geographic variation in mortality from substance use disorders and intentional injuries among US counties, 1980–2014. JAMA. 2018;319(10):1013–23.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Van Handel MM, Rose CE, Hallisey EJ, Kolling JL, Zibbell JE, Lewis B, et al. County-level vulnerability assessment for rapid dissemination of HIV or HCV infections among persons who inject drugs, United States. J Acquir Immune Defic Syndr. 2016;73(3):323–31.

    Article  PubMed  PubMed Central  Google Scholar 

  11. Ciccarone D, Unick GJ, Cohen JK, Mars SG, Rosenblum D. Nationwide increase in hospitalizations for heroin-related soft tissue infections: associations with structural market conditions. Drug Alcohol Depend. 2016;163:126–33.

    Article  PubMed  PubMed Central  Google Scholar 

  12. U.S. Department of Health and Human Services (HHS), Office of the Surgeon General. Facing addiction in America: The Surgeon General’s Report on alcohol, drugs, and health. Washington, DC: HHS; 2016. [cited 2018 Aug 26]. Available at: https://addiction.surgeongeneral.gov/.

    Google Scholar 

  13. Sordo L, Barrio G, Bravo MJ, Indave BI, Degenhardt L, Wiessing L, et al. Mortality risk during and after opioid substitution treatment: systematic review and meta-analysis of cohort studies. BMJ. 2017;357:j1550.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Larochelle MR, Bernson D, Land T, Stopka TJ, Wang N, Xuan Z, et al. Medication for opioid use disorder after nonfatal opioid overdose and association with mortality: a cohort study. Ann Intern Med. 2018;169(3):137–45.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Lee JD, Friedmann PD, Kinlock TW, Nunes EV, Boney TY, Hoskinson RA Jr, et al. Extended-release naltrexone to prevent opioid relapse in criminal justice offenders. N Engl J Med. 2016;374(13):1232–42.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  16. Jarvis BP, Holtyn AF, Subramaniam S, Tompkins DA, Oga EA, Bigelow GE, et al. Extended-release injectable naltrexone for opioid use disorder: a systematic review. Addiction. 2018;113(7):1188–209.

    Article  PubMed  PubMed Central  Google Scholar 

  17. Strang J, Babor T, Caulkins J, Fischer B, Foxcroft D, Humphreys K. Drug policy and the public good: evidence for effective interventions. Lancet. 2012;379(9810):71–83.

    Article  PubMed  Google Scholar 

  18. Dutra L, Stathopoulou G, Basden SL, Leyro TM, Powers MB, Otto MW. A meta-analytic review of psychosocial interventions for substance use disorders. Am J Psychiatry. 2008;165(2):179–87.

    Article  PubMed  Google Scholar 

  19. Sullivan MA, Birkmayer F, Boyarsky BK, Frances RJ, Fromson JA, Galanter M, et al. Uses of coercion in addiction treatment: clinical aspects. Am J Addict. 2008;17(1):36–47.

    Article  PubMed  Google Scholar 

  20. Beletsky L, Parmet WE, Sarpatwari A. Expanding coercive treatment is the wrong solution for the opioid crisis. 11 Feb 2016 [cited 26 Aug 2018]. In: Health Affairs Blog [Internet]. Available at: https://www.healthaffairs.org/do/10.1377/hblog20160211.053127/full/.

  21. Werb D, Kamarulzaman A, Meacham MC, Rafful C, Fischer B, Strathdee SA, et al. The effectiveness of compulsory drug treatment: a systematic review. Int J Drug Policy. 2016;28:1–9.

    Article  CAS  PubMed  Google Scholar 

  22. Epstein RM, Street RL Jr. The values and value of patient-centered care. Ann Fam Med. 2011;9(2):100–3.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Rosenblatt RA, Andrilla CH, Catlin M, Larson EH. Geographic and specialty distribution of US physicians trained to treat opioid use disorder. Ann Fam Med. 2015;13(1):23–6.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Kvamme E, Catlin M, Banta-Green C, Roll J, Rosenblatt R. Who prescribes buprenorphine for rural patients? The impact of specialty, location and practice type in Washington state. J Subst Abus Treat. 2013;44(3):355–60.

    Article  Google Scholar 

  25. Buck JA. The looming expansion and transformation of public substance abuse treatment under the Affordable Care Act. Health Aff (Millwood). 2011;30(8):1402–10.

    Article  Google Scholar 

  26. Jackson H, Mandell K, Johnson K, Chatterjee D, Vanness DJ. Cost-effectiveness of injectable extended-release naltrexone compared with methadone maintenance and buprenorphine maintenance treatment for opioid dependence. Subst Abus. 2015;36(2):226–31.

    Article  PubMed  PubMed Central  Google Scholar 

  27. Abraham AJ, Andrews CM, Grogan CM, D’Aunno T, Humphreys KN, Pollack HA, et al. The affordable care act transformation of substance use disorder treatment. Am J Public Health. 2017;107(1):31–2.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Substance Abuse and Mental Health Services Administration. Receipt of services for substance use and mental health issues among adults: results from the 2016 National Survey on Drug Use and Health. Sep 2017 [cited 26 Aug 2018]. In: NSDUH Data Review [Internet]. Available at: https://www.samhsa.gov/data/sites/default/files/NSDUH-DR-FFR2-2016/NSDUH-DR-FFR2-2016.htm.

  29. Substance Abuse and Mental Health Services Administration. National Survey of Substance Abuse Treatment Services (N-SSATS): 2016. Data on Substance Abuse Treatment Facilities. BHSIS Series S-93, HHS Publication No. SMA 17–5039. Rockville: Substance Abuse and Mental Health Services Administration; 2017. [cited 26 Aug 2018]. Available at: https://www.samhsa.gov/data/sites/default/files/2016_NSSATS.pdf.

    Google Scholar 

  30. Center for Substance Abuse Treatment. Clinical guidelines for the use of buprenorphine in the treatment of opioid addiction. Treatment Improvement Protocol (TIP) Series 40. DHHS Publication No. SMA 04-3939. Rockville: Substance Abuse and Mental Health Services Administration; 2004.

    Google Scholar 

  31. Zur J, Tolbert J, Sharac J, Markus A. The role of community health centers in addressing the opioid epidemic [Internet]. San Francisco: Kaiser Family Foundation; 2018. [cited 26 Aug 2018]. Available at: https://www.kff.org/medicaid/issue-brief/the-role-of-community-health-centers-in-addressing-the-opioid-epidemic/.

    Google Scholar 

  32. Krawczyk N, Picher CE, Feder KA, Saloner B. Only one in twenty justice-referred adults in specialty treatment for opioid use receive methadone or buprenorphine. Health Aff (Millwood). 2017;36(12):2046–53.

    Article  Google Scholar 

  33. Cummings JR, Wen H, Ko M, Druss BG. Race/ethnicity and geographic access to Medicaid substance use disorder treatment facilities in the United States. JAMA Psychiat. 2014;71(2):190–6.

    Article  Google Scholar 

  34. Mark TL, Levit KR, Vandivort-Warren R, Buck JA, Coffey RM. Changes in US spending on mental health and substance abuse treatment, 1986–2005, and implications for policy. Health Aff (Millwood). 2011;30(2):284–92.

    Article  Google Scholar 

  35. Perron BE, Gillespie DF, Alexander-Eitzman B, Delva J. Availability of outpatient substance use disorder treatment programs in the United States. Subst Use Misuse. 2010;45(7–8):1097–111.

    Article  PubMed  Google Scholar 

  36. Miller WR, Sorensen JL, Selzer JA, Brigham GS. Disseminating evidence-based practices in substance abuse treatment: a review with suggestions. J Subst Abus Treat. 2006;31(1):25–39.

    Article  Google Scholar 

  37. Volkow ND, Koob GF, McLellan AT. Neurobiologic advances from the brain disease model of addiction. N Engl J Med. 2016;374(4):363–71.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  38. Prochaska JO, DiClemente CC, Norcross JC. In search of how people change. Applications to addictive behaviors. Am Psychol. 1992;47(9):1102–14.

    Article  CAS  PubMed  Google Scholar 

  39. Graham K, Brett PJ, Bois C. Treatment entry and engagement: a study of the process at assessment/referral centers. Contemp Drug Probl. 1995;22(1):61–104.

    Article  Google Scholar 

  40. Heller D, McCoy K, Cunningham C. An invisible barrier to integrating HIV primary care with harm reduction services: philosophical clashes between the harm reduction and medical models. Public Health Rep. 2004;119(1):32–9.

    Article  PubMed  PubMed Central  Google Scholar 

  41. Rosenblum A, Magura S, Joseph H. Ambivalence toward methadone treatment among intravenous drug users. J Psychoactive Drugs. 1991;23(1):21–7.

    Article  CAS  PubMed  Google Scholar 

  42. Fox AD, Sohler NL, Frost T, Lopez C, Cunningham CO. Development and evaluation of a community-based buprenorphine treatment intervention. Harm Reduct J. 2017;14(1):23.

    Article  PubMed  PubMed Central  Google Scholar 

  43. Kidorf M, King VL, Neufeld K, Peirce J, Kolodner K, Brooner RK. Improving substance abuse treatment enrollment in community syringe exchangers. Addiction. 2009;104(5):786–95.

    Article  PubMed  Google Scholar 

  44. Donovan DM, Rosengren DB, Downey L, Cox GB, Sloan KL. Attrition prevention with individuals awaiting publicly funded drug treatment. Addiction. 2001;96(8):1149–60.

    Article  CAS  PubMed  Google Scholar 

  45. Major B, Dovidio JF, Link BG, Calabrese SL. Stigma and its implications for health: introduction and overview. In: Major B, Dovidio JF, Link BG, editors. The Oxford handbook of stigma, discrimination, and health. New York: Oxford University Press; 2018.

    Google Scholar 

  46. Link BG, Struening EL, Rahav M, Phelan JC, Nuttbrock L. On stigma and its consequences: evidence from a longitudinal study of men with dual diagnoses of mental illness and substance abuse. J Health Soc Behav. 1997;38(2):177–90.

    Article  CAS  PubMed  Google Scholar 

  47. Ahern J, Stuber J, Galea S. Stigma, discrimination and the health of illicit drug users. Drug Alcohol Depend. 2007;88(2–3):188–96.

    Article  PubMed  Google Scholar 

  48. Paquette CE, Syvertsen JL, Pollini RA. Stigma at every turn: health services experiences among people who inject drugs. Int J Drug Policy. 2018;57:104–10.

    Article  PubMed  PubMed Central  Google Scholar 

  49. van Boekel LC, Brouwers EP, van Weeghel J, Garretsen HF. Stigma among health professionals towards patients with substance use disorders and its consequences for healthcare delivery: systematic review. Drug Alcohol Depend. 2013;131(1–2):23–35.

    Article  PubMed  Google Scholar 

  50. Kennedy-Hendricks A, Busch SH, McGinty EE, Bachhuber MA, Niederdeppe J, Gollust SE, et al. Primary care physicians’ perspectives on the prescription opioid epidemic. Drug Alcohol Depend. 2016;165:61–70.

    Article  PubMed  PubMed Central  Google Scholar 

  51. Earnshaw V, Smith L, Copenhaver M. Drug addiction stigma in the context of methadone maintenance therapy: an investigation into understudied sources of stigma. Int J Ment Health Addiction. 2013;11(1):110–22.

    Article  Google Scholar 

  52. Maradiaga JA, Nahvi S, Cunningham CO, Sanchez J, Fox AD. “I kicked the hard way. I got incarcerated”. Withdrawal from methadone during incarceration and subsequent aversion to medication assisted treatments. J Subst Abus Treat. 2016;62:49–54.

    Article  Google Scholar 

  53. Merrill JO, Rhodes LA, Deyo RA, Marlatt GA, Bradley KA. Mutual mistrust in the medical care of drug users: the keys to the “narc” cabinet. J Gen Intern Med. 2002;17(5):327–33.

    PubMed  PubMed Central  Google Scholar 

  54. Olsen Y, Sharfstein JM. Confronting the stigma of opioid use disorder–and its treatment. JAMA. 2014;311(14):1393–4.

    Article  PubMed  CAS  Google Scholar 

  55. Fox AD, Maradiaga J, Weiss L, Sanchez J, Starrels JL, Cunningham CO. Release from incarceration, relapse to opioid use and the potential for buprenorphine maintenance treatment: a qualitative study of the perceptions of former inmates with opioid use disorder. Addict Sci Clin Pract. 2015;10:2.

    Article  PubMed  PubMed Central  Google Scholar 

  56. White WL. Long-term strategies to reduce the stigma attached to addiction, treatment, and recovery within the city of Philadelphia [Internet]. Philadelphia: Department of Behavioral Health and Intellectual Disability Services; 2009. [cited 26 Aug 2018]. Available at: http://dbhids.org/technical-papers-on-recovery-transformation/.

    Google Scholar 

  57. Harper J. Price’s remarks on opioid treatment were unscientific and damaging, Experts Say. 16 May 2017 [cited 26 Aug 2018]. In: Shots: Health News From NPR [Internet]. Available at: https://www.npr.org/sections/health-shots/2017/05/16/528614422/prices-remarks-on-opioid-treatment-were-unscientific-and-damaging-experts-say.

  58. Livingston JD, Milne T, Fang ML, Amari E. The effectiveness of interventions for reducing stigma related to substance use disorders: a systematic review. Addiction. 2012;107(1):39–50.

    Article  PubMed  PubMed Central  Google Scholar 

  59. Kelly JF, Westerhoff CM. Does it matter how we refer to individuals with substance-related conditions? A randomized study of two commonly used terms. Int J Drug Policy. 2010;21(3):202–7.

    Article  PubMed  Google Scholar 

  60. Greenwald G. Drug decriminalization in Portugal: lessons for creating fair and successful drug policies [Internet]. Washington, DC: Cato Institute; 2009. [cited 26 Aug 2018]. Available at: https://www.cato.org/publications/white-paper/drug-decriminalization-portugal-lessons-creating-fair-successful-drug-policies.

    Google Scholar 

  61. Satel SL. Drug treatment: the case for coercion [Internet]. Washington, DC: American Enterprise Institute; 1999. [cited 26 Aug 2018]. Available at: http://www.aei.org/wp-content/uploads/2014/07/-drug-treatment_104032428225.pdf.

    Google Scholar 

  62. Bart G. Maintenance medication for opiate addiction: the foundation of recovery. J Addict Dis. 2012;31(3):207–25.

    Article  PubMed  PubMed Central  Google Scholar 

  63. Mattick RP, Breen C, Kimber J, Davoli M. Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence. Cochrane Database Syst Rev. 2014;(2):CD002207.

    Google Scholar 

  64. Barry DT, Moore BA, Pantalon MV, Chawarski MC, Sullivan LE, O’Connor PG, et al. Patient satisfaction with primary care office-based buprenorphine/naloxone treatment. J Gen Intern Med. 2007;22(2):242–5.

    Article  PubMed  PubMed Central  Google Scholar 

  65. Hunt DE, Lipton DS, Goldsmith DS, Strug DL, Spunt B. “It takes your heart”: the image of methadone maintenance in the addict world and its effect on recruitment into treatment. Int J Addict. 1985;20(11–12):1751–71.

    Article  CAS  PubMed  Google Scholar 

  66. Reisinger HS, Schwartz RP, Mitchell SG, Peterson JA, Kelly SM, O’Grady KE, et al. Premature discharge from methadone treatment: patient perspectives. J Psychoactive Drugs. 2009;41(3):285–96.

    Article  PubMed  PubMed Central  Google Scholar 

  67. Lamb S, Greenlick MR, McCarty D. Bridging the gap between practice and research: forging partnerships with community-based drug and alcohol treatment. Washington, DC: National Academies Press; 1998. [cited 26 Aug 2018]. Available at: http://www.nap.edu/catalog/6169/bridging-the-gap-between-practice-and-research-forging-partnerships-with.

    Google Scholar 

  68. White WL, Miller WR. The use of confrontation in addiction treatment: history, science and time for change. Counselor. 2007;4:12–30.

    Google Scholar 

  69. Bale RN, Van Stone WW, Kuldau JM, Engelsing TM, Elashoff RM, Zarcone VP Jr. Therapeutic communities vs methadone maintenance. A prospective controlled study of narcotic addiction treatment: design and one-year follow-up. Arch Gen Psychiatry. 1980;37(2):179–93.

    Article  CAS  PubMed  Google Scholar 

  70. Fischer B, Chin AT, Kuo I, Kirst M, Vlahov D. Canadian illicit opiate users’ views on methadone and other opiate prescription treatment: an exploratory qualitative study. Subst Use Misuse. 2002;37(4):495–522.

    Article  PubMed  Google Scholar 

  71. Stein BD, Gordon AJ, Sorbero M, Dick AW, Schuster J, Farmer C. The impact of buprenorphine on treatment of opioid dependence in a Medicaid population: recent service utilization trends in the use of buprenorphine and methadone. Drug Alcohol Depend. 2012;123(1–3):72–8.

    Article  CAS  PubMed  Google Scholar 

  72. Awgu E, Magura S, Rosenblum A. Heroin-dependent inmates’ experiences with buprenorphine or methadone maintenance. J Psychoactive Drugs. 2010;42(3):339–46.

    Article  PubMed  PubMed Central  Google Scholar 

  73. Schwartz RP, Kelly SM, O’Grady KE, Mitchell SG, Peterson JA, Reisinger HS, et al. Attitudes toward buprenorphine and methadone among opioid-dependent individuals. Am J Addict. 2008;17(5):396–401.

    Article  PubMed  PubMed Central  Google Scholar 

  74. Yarborough BJ, Stumbo SP, McCarty D, Mertens J, Weisner C, Green CA. Methadone, buprenorphine and preferences for opioid agonist treatment: a qualitative analysis. Drug Alcohol Depend. 2016;160:112–8.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  75. Fox AD, Masyukova M, Cunningham CO. Optimizing psychosocial support during office-based buprenorphine treatment in primary care: patients’ experiences and preferences. Subst Abus. 2016;37(1):70–5.

    Article  PubMed  Google Scholar 

  76. ASAM.org [Internet]. Rockville (MD): American Society of Addiction Medicine; [cited 26 Aug 2018]. Available from: https://www.asam.org/resources/definition-of-addiction.

  77. Goldstein RZ, Volkow ND. Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications. Nat Rev Neurosci. 2011;12(11):652–69.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  78. Miller WR, Benefield RG, Tonigan JS. Enhancing motivation for change in problem drinking: a controlled comparison of two therapist styles. J Consult Clin Psychol. 1993;61(3):455–61.

    Article  CAS  PubMed  Google Scholar 

  79. Miller WR, Benefield RG, Tonigan TS. Enhancing motivation for change in problem drinking: a controlled comparison of two therapist styles. J Consult Clin Psychol. 1993;61:455–61.

    Article  CAS  PubMed  Google Scholar 

  80. Rohrer GE, Thomas M, Yasenchak AB. Client perceptions of the ideal addictions counselor. Int J Addict. 1992;27(6):727–33.

    Article  CAS  PubMed  Google Scholar 

  81. Kelly JF, Myers MG, Rodolico J. What do adolescents exposed to alcoholics anonymous think about 12-step groups? Subst Abus. 2008;29(2):53–62.

    Article  PubMed  Google Scholar 

  82. Woody G, O’Hare K, Mintz J, O’Brien C. Rapid intake: a method for increasing retention rate of heroin addicts seeking methadone treatment. Compr Psychiatry. 1975;16(2):165–9.

    Article  CAS  PubMed  Google Scholar 

  83. Dennis ML, Ingram PW, Burks ME, Rachal JV. Effectiveness of streamlined admissions to methadone treatment: a simplified time-series analysis. J Psychoactive Drugs. 1994;26(2):207–16.

    Article  CAS  PubMed  Google Scholar 

  84. Friedmann PD, Lemon SC, Stein MD, D’Aunno TA. Accessibility of addiction treatment: results from a national survey of outpatient substance abuse treatment organizations. Health Serv Res. 2003;38(3):887–903.

    Article  PubMed  PubMed Central  Google Scholar 

  85. McLellan AT, Arndt IO, Metzger DS, Woody GE, O’Brien CP. The effects of psychosocial services in substance abuse treatment. JAMA. 1993;269(15):1953–9.

    Article  CAS  PubMed  Google Scholar 

  86. Amato L, Minozzi S, Davoli M, Vecchi S. Psychosocial combined with agonist maintenance treatments versus agonist maintenance treatments alone for treatment of opioid dependence. Cochrane Database Syst Rev. 2011;(10):CD004147.

    Google Scholar 

  87. Schwartz RP, Kelly SM, Mitchell SG, Gryczynski J, O’Grady KE, Gandhi D, et al. Patient-centered methadone treatment: a randomized clinical trial. Addiction. 2017;112(3):454–64.

    Article  PubMed  Google Scholar 

  88. Mitchell SG, Monico LB, Lertch E, Kelly SM, Gryczynski J, Jaffe JH, et al. Counseling staff’s views of patient-centered methadone treatment: changing program rules and staff roles. J Behav Health Serv Res. 2018;45(3):506–15.

    Article  PubMed  Google Scholar 

  89. Ahamad K, Hayashi K, Nguyen P, Dobrer S, Kerr T, Schutz CG, et al. Effect of low-threshold methadone maintenance therapy for people who inject drugs on HIV incidence in Vancouver, BC, Canada: an observational cohort study. Lancet HIV. 2015;2(10):e445–50.

    Article  PubMed  PubMed Central  Google Scholar 

  90. Nolan S, Hayashi K, Milloy MJ, Kerr T, Dong H, Lima VD, et al. The impact of low-threshold methadone maintenance treatment on mortality in a Canadian setting. Drug Alcohol Depend. 2015;156:57–61.

    Article  PubMed  PubMed Central  Google Scholar 

  91. Fischer B, Cape D, Daniel N, Gliksman L. Methadone treatment in Ontario after the 1996 regulation reforms. Results of a physician survey. Ann Med Interne (Paris). 2002;153(7 Suppl):2S11–21.

    Google Scholar 

  92. Fiellin DA, O’Connor PG, Chawarski M, Pakes JP, Pantalon MV, Schottenfeld RS. Methadone maintenance in primary care: a randomized controlled trial. JAMA. 2001;286(14):1724–31.

    Article  CAS  PubMed  Google Scholar 

  93. Tuchman E, Gregory C, Simson M, Drucker E. Safety, efficacy, and feasibility of office-based prescribing and community pharmacy dispensing of methadone. Addict Disord Their Treat. 2006;5(2):43–51.

    Article  Google Scholar 

  94. Merrill JO, Jackson TR, Schulman BA, Saxon AJ, Awan A, Kapitan S, et al. Methadone medical maintenance in primary care. An implementation evaluation. J Gen Intern Med. 2005;20(4):344–9.

    Article  PubMed  PubMed Central  Google Scholar 

  95. Drucker E, Rice S, Ganse G, Kegley JJ, Bonuck K, Tuchman E. The Lancaster office based opiate treatment program: a case study and prototype for community physicians and pharmacists providing methadone maintenance treatment in the United States. Addict Disord Their Treat. 2007;6(3):121–5.

    Article  Google Scholar 

  96. Samet JH, Botticelli M, Bharel M. Methadone in primary care – one small step for congress, one giant leap for addiction treatment. N Engl J Med. 2018;379(1):7–8.

    Article  PubMed  Google Scholar 

  97. Kwan TH, Wong NS, Lee SS. Participation dynamics of a cohort of drug users in a low-threshold methadone treatment programme. Harm Reduct J. 2015;12:30.

    Article  PubMed  PubMed Central  Google Scholar 

  98. Strike C, Millson M, Hopkins S, Smith C. What is low threshold methadone maintenance treatment? Int J Drug Policy. 2013;24(6):e51–6.

    Article  PubMed  Google Scholar 

  99. van Ameijden EJ, Langendam MW, Coutinho RA. Dose-effect relationship between overdose mortality and prescribed methadone dosage in low-threshold maintenance programs. Addict Behav. 1999;24(4):559–63.

    Article  PubMed  Google Scholar 

  100. Ryrie IW, Dickson J, Robbins C, Maclean K, Climpson C. Evaluation of a low-threshold clinic for opiate-dependent drug users. J Psychiatr Ment Health Nurs. 1997;4(2):105–10.

    Article  CAS  PubMed  Google Scholar 

  101. Langendam MW, van Brussel GH, Coutinho RA, van Ameijden EJ. The impact of harm-reduction-based methadone treatment on mortality among heroin users. Am J Public Health. 2001;91(5):774–80.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  102. Millson P, Challacombe L, Villeneuve PJ, Strike CJ, Fischer B, Myers T, et al. Reduction in injection-related HIV risk after 6 months in a low-threshold methadone treatment program. AIDS Educ Prev. 2007;19(2):124–36.

    Article  PubMed  Google Scholar 

  103. Comer S, Cunningham C, Fishman MJ, et al. National Practice Guideline for the use of medications in the treatment of addiction involving opioid use ASAM National Practice Guideline for the use of medications in the treatment of addiction involving opioid use [Internet]. Chevy Chase: American Society of Addiction Medicine; 2015. [cited 26 Aug 2018]. Available from: https://www.asam.org/docs/default-source/practice-support/guidelines-and-consensus-docs/asam-national-practice-guideline-supplement.pdf?sfvrsn=24.

    Google Scholar 

  104. Walley AY, Alperen JK, Cheng DM, Botticelli M, Castro-Donlan C, Samet JH, et al. Office-based management of opioid dependence with buprenorphine: clinical practices and barriers. J Gen Intern Med. 2008;23(9):1393–8.

    Article  PubMed  PubMed Central  Google Scholar 

  105. Gunderson EW, Wang XQ, Fiellin DA, Bryan B, Levin FR. Unobserved versus observed office buprenorphine/naloxone induction: a pilot randomized clinical trial. Addict Behav. 2010;35(5):537–40.

    Article  PubMed  PubMed Central  Google Scholar 

  106. Cunningham CO, Giovanniello A, Li X, Kunins HV, Roose RJ, Sohler NL. A comparison of buprenorphine induction strategies: patient-centered home-based inductions versus standard-of-care office-based inductions. J Subst Abus Treat. 2011;40(4):349–56.

    Article  Google Scholar 

  107. Lee JD, Grossman E, DiRocco D, Gourevitch MN. Home buprenorphine/naloxone induction in primary care. J Gen Intern Med. 2009;24(2):226–32.

    Article  PubMed  Google Scholar 

  108. Weiss RD, Potter JS, Fiellin DA, Byrne M, Connery HS, Dickinson W, et al. Adjunctive counseling during brief and extended buprenorphine-naloxone treatment for prescription opioid dependence: a 2-phase randomized controlled trial. Arch Gen Psychiatry. 2011;68(12):1238–46.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  109. Fiellin DA, Barry DT, Sullivan LE, Cutter CJ, Moore BA, O’Connor PG, et al. A randomized trial of cognitive behavioral therapy in primary care-based buprenorphine. Am J Med. 2013;126(1):74.e11–7.

    Article  CAS  Google Scholar 

  110. Ling W, Hillhouse M, Ang A, Jenkins J, Fahey J. Comparison of behavioral treatment conditions in buprenorphine maintenance. Addiction. 2013;108(10):1788–98.

    Article  PubMed  Google Scholar 

  111. Tetrault JM, Moore BA, Barry DT, O’Connor PG, Schottenfeld R, Fiellin DA, et al. Brief versus extended counseling along with buprenorphine/naloxone for HIV-infected opioid dependent patients. J Subst Abus Treat. 2012;43(4):433–9.

    Article  Google Scholar 

  112. Mintzer IL, Eisenberg M, Terra M, MacVane C, Himmelstein DU, Woolhandler S. Treating opioid addiction with buprenorphine-naloxone in community-based primary care settings. Ann Fam Med. 2007;5(2):146–50.

    Article  PubMed  PubMed Central  Google Scholar 

  113. Parran TV, Adelman CA, Merkin B, Pagano ME, Defranco R, Ionescu RA, et al. Long-term outcomes of office-based buprenorphine/naloxone maintenance therapy. Drug Alcohol Depend. 2010;106(1):56–60.

    Article  CAS  PubMed  Google Scholar 

  114. Alford DP, LaBelle CT, Richardson JM, O’Connell JJ, Hohl CA, Cheng DM, et al. Treating homeless opioid dependent patients with buprenorphine in an office-based setting. J Gen Intern Med. 2007;22(2):171–6.

    Article  PubMed  PubMed Central  Google Scholar 

  115. Fox AD, Chamberlain A, Frost T, Cunningham CO. Harm reduction agencies as a potential site for buprenorphine treatment. Subst Abus. 2015;36(2):155–60.

    Article  PubMed  PubMed Central  Google Scholar 

  116. Stancliff S, Joseph H, Fong C, Furst T, Comer SD, Roux P. Opioid maintenance treatment as a harm reduction tool for opioid-dependent individuals in new York City: the need to expand access to buprenorphine/naloxone in marginalized populations. J Addict Dis. 2012;31(3):278–87.

    Article  PubMed  PubMed Central  Google Scholar 

  117. Bachhuber MA, Thompson C, Prybylowski A, Benitez J, Mazzella S, Barclay D. Description and outcomes of a buprenorphine maintenance treatment program integrated within prevention point Philadelphia, an urban syringe exchange program. Subst Abus. 2018;23:1–6. [Epub ahead of print].

    Google Scholar 

  118. McLellan AT, Carise D, Kleber HD. Can the national addiction treatment infrastructure support the public’s demand for quality care? J Subst Abus Treat. 2003;25(2):117–21.

    Article  Google Scholar 

  119. Moyers TB, Miller WR. Is low therapist empathy toxic? Psychol Addict Behav. 2013;27(3):878–84.

    Article  PubMed  Google Scholar 

  120. Kasarabada ND, Hser YI, Boles SM, Huang YC. Do patients’ perceptions of their counselors influence outcomes of drug treatment? J Subst Abus Treat. 2002;23(4):327–34.

    Article  Google Scholar 

  121. Smedslund G, Berg RC, Hammerstrom KT, Steiro A, Leiknes KA, Dahl HM, et al. Motivational interviewing for substance abuse. Cochrane Database Syst Rev. 2011;(5):CD008063.

    Google Scholar 

  122. Greenfield SF, Brooks AJ, Gordon SM, Green CA, Kropp F, McHugh RK, et al. Substance abuse treatment entry, retention, and outcome in women: a review of the literature. Drug Alcohol Depend. 2007;86(1):1–21.

    Article  PubMed  Google Scholar 

  123. Greenfield SF, Grella CE. What is “women-focused” treatment for substance use disorders? Psychiatr Serv. 2009;60(7):880–2.

    Article  PubMed  PubMed Central  Google Scholar 

  124. Senreich E. Are specialized LGBT program components helpful for gay and bisexual men in substance abuse treatment? Subst Use Misuse. 2010;45(7–8):1077–96.

    Article  PubMed  Google Scholar 

  125. Tyndall MW, Kerr T, Zhang R, King E, Montaner JG, Wood E. Attendance, drug use patterns, and referrals made from North America’s first supervised injection facility. Drug Alcohol Depend. 2006;83(3):193–8.

    Article  PubMed  Google Scholar 

  126. McLellan AT, Kushner H, Metzger D, Peters R, Smith I, Grissom G, et al. The fifth edition of the addiction severity index. J Subst Abus Treat. 1992;9(3):199–213.

    Article  CAS  Google Scholar 

  127. ASAM.org [Internet]. Rockville (MD): American Society of Addiction Medicine; [cited 26 Aug 2018]. Available from: https://www.asam.org/resources/the-asam-criteria.

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Fox, A.D., Jakubowski, A.U., Giftos, J. (2019). Enhancing Treatment Access and Effectiveness: Toward Patient-Centered Models of Care. In: Kelly, J., Wakeman, S. (eds) Treating Opioid Addiction. Current Clinical Psychiatry. Humana, Cham. https://doi.org/10.1007/978-3-030-16257-3_10

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