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Nutriepigenomic Immunity

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Nutrition and Immunity

Abstract

Epigenetic mechanisms and regulatory factors organize a flexible machinery by means of which multicellular organisms generate a heritable alteration in gene expression with respect to the fluctuating external environment. Epigenetic modifications by clever manipulation of maternal dietary and care can transpire independent of DNA sequences to shape a baby and future adult rich not only in immunity to physical diseases – particularly from chronic non-communicable (metabolic and cardiovascular diseases, cancers, and aging) diseases point of view – but also to brain and behavioral disorders. Therefore, despite the book’s dictum to discuss the link between nutrition and immune system function from different aspects, the present chapter first goes beyond to reach that the maternal diet does not leave indiscriminate marks on the offspring epigenome but does plan to manipulate it in a careful pattern and then ends with a nudge to nutriepigenomic immunity.

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Authors and Affiliations

  1. Research Center for Immunodeficiencies, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran

    Amene Saghazadeh & Nima Rezaei

  2. MetaCognition Interest Group (MCIG), Universal Scientific Education and Research Network (USERN), Tehran, Iran

    Amene Saghazadeh

  3. Systematic Review and Meta-analysis Expert Group (SRMEG), Universal Scientific Education and Research Network (USERN), Tehran, Iran

    Amene Saghazadeh

  4. Department of Cellular and Molecular Nutrition, School of Nutrition and Dietetics, Tehran University of Medical Sciences, Tehran, Iran

    Maryam Mahmoudi

  5. Dietitians and Nutrition Experts Team (DiNET), Universal Scientific Education and Research Network (USERN), Tehran, Iran

    Maryam Mahmoudi

  6. Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

    Nima Rezaei

  7. Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran

    Nima Rezaei

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  1. Amene Saghazadeh
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  3. Nima Rezaei
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Correspondence to Nima Rezaei .

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Editors and Affiliations

  1. Department Cellular and Molecular Nutrition, Tehran University of Medical Sciences and Dietitians and Nutrition Experts Team (DiNET), Universal Scientific Education and Research Network (USERN), Tehran, Iran

    Maryam Mahmoudi

  2. Research Center for Immunodeficiencies, Tehran University of Medical Sciences and Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran

    Nima Rezaei

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Saghazadeh, A., Mahmoudi, M., Rezaei, N. (2019). Nutriepigenomic Immunity. In: Mahmoudi, M., Rezaei, N. (eds) Nutrition and Immunity. Springer, Cham. https://doi.org/10.1007/978-3-030-16073-9_25

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  • DOI: https://doi.org/10.1007/978-3-030-16073-9_25

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-16072-2

  • Online ISBN: 978-3-030-16073-9

  • eBook Packages: MedicineMedicine (R0)

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