Abstract
Innovation in the pharmaceutical industry yields immense social good when it aims to address fundamental global health challenges. However, millions worldwide lack access to these innovations and continue to die from preventable and treatable diseases. Without universal patient access, the value of innovative products is diminished because their ability to generate positive health outcomes is restricted. In conjunction with product innovation, a parallel track of innovation in access is needed. Steps are proposed for adopting a more access-oriented approach to innovation.
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References
Branswell H. WHO readies to test Merck’s experimental Ebola vaccine in Congo outbreak. In: STAT, 11 May 2018. https://www.statnews.com/2018/05/11/who-merck-ebola-vaccine-congo/. Accessed 13 Mar 2019.
Bill & Melinda Gates Foundation [1]. What We Do: Malaria. https://www.gatesfoundation.org/What-We-Do/Global-Health/Malaria. Accessed 13 Mar 2019.
Bill & Melinda Gates Foundation [2]. What We Do: HIV. https://www.gatesfoundation.org/What-We-Do/Global-Health/HIV. Accessed 13 Mar 2019.
Bill & Melinda Gates Foundation [3]. What We Do: Global Vaccine Delivery. https://www.gatesfoundation.org/What-We-Do/Global-Development/Vaccine-Delivery. Accessed 13 Mar 2019.
Booth O. Top 10 Causes of Death in Developing Countries. In: The Borgen Project: the blog. https://borgenproject.org/causes-of-death-in-developing-countries/, 31 Mar 2018. Accessed 13 Mar 2019.
Center for Disease Control. Seasonal flu death estimate increases worldwide (press release), 13 Dec 2017. https://www.cdc.gov/media/releases/2017/p1213-flu-death-estimate.html. Accessed 13 Mar 2019.
GAVI: The Vaccine Alliance. https://www.gavi.org/ (2019). Accessed 13 Mar 2019.
Hersh LB, Newland JG, Beekmann SE, Polgreen PM, Gilbert DN, Unmet Medical Need in Infectious Diseases. In: Clinical Infectious Diseases 2012;54(11):1677–8. https://doi.org/10.1093/cid/cis275, https://www.researchgate.net/publication/223986634_Unmet_Medical_Need_in_Infectious_Diseases. Accessed 13 Mar 2019.
Hirschler B. GlaxoSmithKline’s new boss streamlines R&D, axes slew of drugs, Reuters, 26 Jul 2017. https://www.reuters.com/article/us-gsk-results/glaxosmithklines-new-boss-streamlines-rd-axes-slew-of-drugs-idUSKBN1AB1BH. Accessed 13 Mar 2019.
Koppaka R. Morbidity and Mortality Weekly Report, 20 May 2011. Center for Disease Control and Prevention. https://www.cdc.gov/mmwr/preview/mmwrhtml/mm6019a5.htm. Accessed 13 Mar 2019.
Morgan S, Lopert R, Greyson D. Toward a definition of pharmaceutical innovation. Open Med 2008;2(1):e4–e7. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091590/. Accessed 13 Mar 2019.
Nathe M. 7 Global health issues to watch in 2017. In: Humanosphere 23 Jan 2017. http://www.humanosphere.org/global-health/2017/01/7-global-health-issues-to-watch-in-2017/. Accessed 13 Mar 2019.
Novartis. Novartis renews commitment to malaria elimination, investing USD 100 million to research and develop next-generation antimalarials (press release), 17 Apr 2018. https://www.novartis.com/news/media-releases/novartis-renews-commitment-malaria-elimination-investing-usd-100-million-research-and-develop-next-generation-antimalarials. Accessed 13 Mar 2019.
Office of Disease Control and Health Prevention, HealthyPeople.gov. https://www.healthypeople.gov/2020/topics-objectives/topic/global-health (2019). Accessed 13 Mar 2019.
Pagliarulo N. 5 trends shaping rare disease drug development. In: Biopharmadive, 10 Apr 2017. https://www.biopharmadive.com/news/trends-rare-disease-orphan-drug-development/439866/. Accessed 13 Mar 2019.
Taubenberger JK, Morens DM. 1918 Influenza: the Mother of All Pandemics. Emerg Infect Dis. 2006;12(1):15–22. https://doi.org/10.3201/eid1201.050979. Accessed 13 Mar 2019.
UNAIDS, Global HIV & AIDS Statistics—2018 Fact Sheet, 2019. http://www.unaids.org/en/resources/fact-sheet. Accessed 13 Mar 2019.
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Saxena, S., Wilcox, I.B. (2019). In the Face of Global Health Challenges—Let’s Redefine Innovation. In: Betz, U. (eds) Curious2018. Springer, Cham. https://doi.org/10.1007/978-3-030-16061-6_8
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DOI: https://doi.org/10.1007/978-3-030-16061-6_8
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