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Inflammatory Bowel Disease

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Abstract

Inflammatory bowel disease (IBD) specifically refers to two idiopathic chronic inflammatory diseases involving the gut: ulcerative colitis (UC) and Crohn’s disease (CD). UC and CD share some clinical and pathological features, and distinction between these two diseases can be difficult in some cases, especially in fulminant phase, and the term “indeterminate colitis” can be used occasionally. UC is usually restricted to the colon and characterized by transmucosal inflammation in a continuous pattern. CD more commonly involves distal small bowel, but over 60% of patients with CD have colonic involvement and 20% of them have colon involvement only. CD is characterized by transmural changes with skip areas and granulomas. The clinicopathological features of UC and CD are discussed in this chapter.

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    Lizhi Zhang & Tsung-Teh Wu

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    Lizhi Zhang

  2. University of California Irvine, Irvine, CA, USA

    Vishal S. Chandan

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    Tsung-Teh Wu

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Zhang, L., Wu, TT. (2019). Inflammatory Bowel Disease. In: Zhang, L., Chandan, V., Wu, TT. (eds) Surgical Pathology of Non-neoplastic Gastrointestinal Diseases. Springer, Cham. https://doi.org/10.1007/978-3-030-15573-5_15

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