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A range of infective and immunological conditions can cause blistering of the orofacial tissues. A small blister is referred to as a vesicle, whilst a blister greater than 0.5 cm is called a bulla. In reality, it is rare to see intact blisters intra-orally since the tissues usually rupture relatively quickly to leave areas of erosion or ulceration. However, the patient will often give a history of a sensation of blistering.
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