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Infectious Diseases in Solid-Organ Transplant Recipients pp 65–80Cite as

Prevention and Treatment of CMV Infection (and Other Herpes Viruses)

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Abstract

Cytomegalovirus (CMV) infection is one of the most common viral infections in solid organ transplant (SOT) recipients. In these patients, CMV is an important cause of morbidity due to the development of invasive disease or due to the immunomodulatory effect of the virus on the host immune system. Other herpes viruses (herpes simplex virus 1 and 2, varicella-zoster virus, Epstein-Barr virus, human herpesvirus 6, 7, and 8) are also an important cause of infection in this setting. Over the last few years, new data and consensus documents on the management of these infections have been created. In this chapter, we provide practical recommendations to guide clinicians on the prevention and treatment of infection due to herpes viruses.

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Acknowledgments

This is supported by Plan Nacional de I+D+i 2013–2016, Instituto de Salud Carlos III, Subdirección General de Redes y Centros de Investigación Cooperativa, Ministerio de Economía, Industria y Competitividad, and Spanish Network for Research in Infectious Diseases (RD16/0016/0008) and co-financed by the European Development Regional Fund “A way to achieve Europe,” Operative Program Intelligent Growth 2014–2020.

Conflict of Interest

JTC has received unrestricted grants and has served as scientific advisor and speaker of Roche Pharma, MSD, Astellas, and Qiagen. AH has received grant support and/or speaker honoraria from Roche, Astellas, Merck, and Qiagen.

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Authors and Affiliations

  1. Maimonides Institute for Biomedical Research (IMIBIC), Reina Sofia University Hospital, University of Córdoba, Córdoba, Spain

    Julian Torre-Cisneros

  2. Transplant Program, University Health Network, Toronto, ON, Canada

    Atul Humar

Authors
  1. Julian Torre-Cisneros
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  2. Atul Humar
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Corresponding author

Correspondence to Julian Torre-Cisneros .

Editor information

Editors and Affiliations

  1. Infectious Diseases Service and Transplantation Center, University Hospital of Lausanne, Lausanne, Switzerland

    Oriol Manuel

  2. School of Medicine, Northwestern University Feinberg, Chicago, IL, USA

    Michael G Ison

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Torre-Cisneros, J., Humar, A. (2019). Prevention and Treatment of CMV Infection (and Other Herpes Viruses). In: Manuel, O., Ison, M. (eds) Infectious Diseases in Solid-Organ Transplant Recipients. Springer, Cham. https://doi.org/10.1007/978-3-030-15394-6_6

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  • DOI: https://doi.org/10.1007/978-3-030-15394-6_6

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-15393-9

  • Online ISBN: 978-3-030-15394-6

  • eBook Packages: MedicineMedicine (R0)

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