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Fibrinolysis

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Patient Blood Management in Cardiac Surgery

Abstract

Cardiac surgery with exposure to an extracorporeal circuit is associated with fibrinolysis. Fibrinolysis results in coagulation factor consumption and an increased risk of bleeding. Antifibrinolytics like tranexamic acid, aprotinin, and ε-aminocaproic acid are therefore administered in a prophylactic fashion with a high level of evidence for the prevention of bleeding and blood transfusions.

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Author information

Authors and Affiliations

  1. Department of Anesthesia, University of Toronto, Toronto, ON, Canada

    David Faraoni

  2. Department of Translational Medicine, SickKids Research Institute, Toronto, ON, Canada

    David Faraoni

  3. Division of Cardiac Anesthesia, Department of Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, ON, Canada

    David Faraoni

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  1. David Faraoni
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Correspondence to David Faraoni .

Editor information

Editors and Affiliations

  1. Vivantes Klinikum im Friedrichshain, Berlin, Germany

    Christian von Heymann

  2. Amsterdam University Medical Center, VU University, Amsterdam, The Netherlands

    Christa Boer

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Faraoni, D. (2019). Fibrinolysis. In: von Heymann, C., Boer, C. (eds) Patient Blood Management in Cardiac Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-15342-7_12

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  • DOI: https://doi.org/10.1007/978-3-030-15342-7_12

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-15341-0

  • Online ISBN: 978-3-030-15342-7

  • eBook Packages: MedicineMedicine (R0)

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