Abstract
Patient hemostasis is historically assessed by laboratory coagulation tests, including the prothrombin time and platelet count. Laboratory tests are however performed in plasma rather than whole blood, and test results are usually not retrieved within a short time period. Their value in the acute setting is therefore limited. With the introduction of point-of-care devices (e.g., thromboelastography, thromboelastometry, and ultrasound based resonance sonorheometry) coagulation and hemostasis monitoring can be performed at a bedside level, and results are frequently available within minutes.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Murphy G, Reeves B, Rogers C, et al. Increased mortality, postoperative morbidity and cost after red blood cell transfusion in patients having cardiac surgery. Circulation. 2007;116:2544–52.
Erdoes G, Martinez Lopez De Arroyabe B, Bolliger D, Ahmed AB, Koster A, Agarwal S, Boer C, von Heymann C. International consensus statement on the peri-operative management of direct oral anticoagulants in cardiac surgery. Anaesthesia. 2018;73:1535–45.
Cuker A, Siegal DM, Crowther MA, Garcia DA. Laboratory measurement of the anticoagulant activity of the non-vitamin K oral anticoagulants. J Am Coll Cardiol. 2014;64:1128–39.
Gosselin RC, Adcock DM, Bates SM, et al. International Council for Standardization in Haematology (ICSH) recommendations for laboratory measurement of direct oral anticoagulants. Thromb Haemost. 2018;118:437–50.
Mallett SV, Cox DJ. Thromboelastography. Br J Anaesth. 1992;69:307–13.
Quarterman C, Shaw M, Johnson I, Agarwal S. Intra- and inter-centre standardisation of TEG. Anaesthesia. 2014;69:883–90.
Bolliger D, Tanaka KA. Roles of thrombelastography and thromboelastometry for patient blood management in cardiac surgery. Transfus Med Rev. 2013;27:213–20.
Huffmyer JL, Fernandez LG, Haghighian C, Terkawi AS, Groves DS. Comparison of SEER Sonorheometry with rotational thromboelastometry and laboratory parameters in cardiac surgery. Anesth Analg. 2016;123:1390–9.
Gurbel PA, Bliden KP, Tantry US, Monroe AL, Muresan AA, et al. First report of the point-of-care TEG: a technical validation study of the TEG-6S system. Platelets. 2016;27:642–9.
Wikkelsø A, Wetterslev J, Møller AM, Afshari A. Thromboelastography (TEG) or thromboelastometry (ROTEM) to monitor haemostatic treatment versus usual care in adults or children with bleeding. Cochrane Database Syst Rev. 2016;(8):CD007871.
Karkouti K, Callum J, Wijeysundera D, et al. Point of care hemostatic testing in cardiac surgery. Circulation. 2016;134:1152–62.
Wikkelsø A, Wetterslev J, Møller AM, Afshari A. Thromboelastography (TEG) or rotational thromboelastometry (ROTEM) to monitor haemostatic treatment in bleeding patients: a systematic review with meta-analysis and trial sequential analysis. Anaesthesia. 2017;72:519–31.
Serraino GF, Murphy GJ. Routine use of viscoelastic blood tests for diagnosis and treatment of coagulopathic bleeding in cardiac surgery: updated systematic review and meta-analysis. Br J Anaesth. 2017;118:823–33.
Meesters MI, Burtman D, van de Ven PM, Boer C. Prediction of postoperative blood loss using thromboelastometry in adult cardiac surgery: cohort study and systematic review. J Cardiothorac Vasc Anesth. 2018;32:141–50.
Lodewyks C, Heinrichs J, Grocott HP, et al. Point-of-care viscoelastic hemostatic testing in cardiac surgery patients: a systematic review and meta-analysis. Can J Anaesth. 2018;65:1333–47.
Ortmann E, Rubino A, Altemini B, Collier T, Besser M, Klein A. Validation of viscoelastic coagulation tests during cardiopulmonary bypass. J Thromb Haemost. 2015;13:1207–16.
Detecting, managing and monitoring haemostasis: viscoelastometric point-of-care testing (ROTEM, TEG and Sonoclot systems). British National Institute of Health and Care Excellence 2014. www.nice.org.uk/guidance/dg13.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2019 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Agarwal, S. (2019). Coagulation Monitoring. In: von Heymann, C., Boer, C. (eds) Patient Blood Management in Cardiac Surgery. Springer, Cham. https://doi.org/10.1007/978-3-030-15342-7_10
Download citation
DOI: https://doi.org/10.1007/978-3-030-15342-7_10
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-15341-0
Online ISBN: 978-3-030-15342-7
eBook Packages: MedicineMedicine (R0)