Skip to main content

Glimpse on Genomics and Breeding in Bitter Gourd: A Crop of the Future for Food, Nutrition and Health Security

  • Chapter
  • First Online:
  • 341 Accesses

Part of the book series: Compendium of Plant Genomes ((CPG))

Abstract

Bitter gourd, Momordica charantia L., family Cucurbitaceae, plausibly originated in eastern Asia, is traditionally cultivated as a vegetable and medicinal crop in tropical and subtropical areas in Asia, South America, East Africa, and the Caribbean. It has a simple genome with 2n = 22 chromosomes having a genome size of around 339 Mb. All parts of this plant, mainly the fruits and the seeds, contain more than 60 phytomedicines active against more than 30 diseases including cancer and diabetes. Single plant selection, mass selection, pedigree selection, and bulk population improvement are common methods are used widely in the bitter gourd improvement program. Recent discovery of gynoecious lines and their genetics will facilitate hybrid breeding. Ample genetic diversity has been found to exist in this crop as assessed by the use of molecular markers. Association mapping led to the detection of molecular markers linked to some fruit traits and content of a couple of phytomedicines. A few molecular genetic maps have been constructed and a number of agroeconomically important qualitative and quantitative fruit traits have been mapped. Recently, a draft genome sequence has also been reported and a few studies on genotyping by sequencing and RAD sequencing have been accomplished.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD   109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  • Basch E, Garbardi S, Ulbricht C (2003) Bitter melon (Momordica charantia): a review of efficacy and safety. Amer J Health-Syst Pharm 60:356–359

    Article  Google Scholar 

  • Behera TK, Behera S, Bharathi LK, Joseph JK (2010) Bitter gourd: botany, horticulture and breeding. In: Janick J (ed) Horticulture reviews. Wiley, Blackwell, pp 101–141

    Google Scholar 

  • Behera TK, Dey SS, Munshi AD, Gaikwad AB, Pal A, Singh I (2009) Sex inheritance and development of gynoecious hybrids in bitter gourd (Momordica charantia L.). Sci Hort 120:130–133

    Article  Google Scholar 

  • Behera TK, Dey SS, Sirohi PS (2006) DBGy-201 and DBGy-202: two gynoecious lines in bitter gourd (Momordica charantia L.) isolated from indigenous source. Indian J Genet 66:61–62

    Google Scholar 

  • Chakravarty HL (1990) Cucurbits of India and their role in the development of vegetable crops. In: Bates DM, Robinson RW, Jeffrey C (eds) Biology and utilization of cucurbitaceae. Cornell University Press, Ithaca, NY, pp 325–334

    Google Scholar 

  • Cui J, Luo S, Niu Y, Huang R, Wen Q, Su J et al (2018) A RAD-based genetic map for anchoring scaffold sequences and identifying QTLs in bitter gourd (Momordica charantia). Front Plant Sci 9:477. https://doi.org/10.3389/fpls.2018.00477

    Article  PubMed  PubMed Central  Google Scholar 

  • Decker-Walters DS (1999) Cucurbits, sanskrit, and the Indo-Aryas. Econ Bot 53:98–112

    Article  Google Scholar 

  • Dey SS, Singh AK, Chandel D, Behera TK (2006) Genetic diversity of bitter gourd (Momordica charantia L.) genotypes revealed by RAPD markers and agronomic traits. Sci Hort 109:21–28

    Article  CAS  Google Scholar 

  • Elshire RJ, Glaubitz JC, Sun Q, Poland JA, Kawamoto K, Buckler ES et al (2011) A robust, simple genotyping-by-sequencing (GBS) approach for high diversity species. PLoS ONE 6:e19379. https://doi.org/10.1371/journal.pone.0019379

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Gaikwad AB, Behera TK, Singh AK, Chandel D, Karihaloo JL, Staub JE (2008) AFLP analysis provides strategies for improvement of bitter gourd (Momordica charantia L.). HortScience 43:127–133

    Article  CAS  Google Scholar 

  • Gangadhara Rao P, Behera TK, Gaikwad AB, Munshi AD, Jat GS, Boopalakrishnan G (2018) Mapping and QTL analysis of gynoecy and earliness in bitter gourd (Momordica charantia L.) using genotyping-by-sequencing (GBS) technology. Front Plant Sci 9:1555. https://doi.org/10.3389/fpls.2018.01555

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Grover JK, Yadav SP (2004) Pharmacological actions and potential uses of Momordica charantia: a review. J Ethnopharmacol 93:123–132

    Article  CAS  PubMed  Google Scholar 

  • Grover JK, Rathi SS, Vats V (2002) Amelioration of experimental diabetic neuropathy and gastropathy in rats following oral administration of plant (Eugenia jambolana, Mucuna pruriens and Tinospora cordifolia) extracts. Indian J Exp Biol 40:273–276

    CAS  PubMed  Google Scholar 

  • He J, Zhao X, Laroche A, Lu ZX, Liu H, Li Z (2014) Geno typing by—sequencing (GBS), an ultimate marker-assisted selection (MAS) tool to accelerate plant breeding. Front Plant Sci 5:484. https://doi.org/10.3389/fpls.2014.00484

    Article  PubMed  PubMed Central  Google Scholar 

  • Heiser CB (1979) The gourd book. University of Oklahoma Press, Norman, OK

    Google Scholar 

  • Iwamoto E, Ishida T (2005) Bisexual flower induction by the application of silver nitrate in gynoecious balsam pear (Momordica charantia L.). Hort Res (Japan) 4:391–395

    Article  CAS  Google Scholar 

  • Jha UC, Roy RP (1989) Hermaphrodite flowers in dioecious Momordica dioica Roxb. Curr Sci 58:1249–1250

    Google Scholar 

  • Kajale MD (1991) Current status of Indian palaeoethnobotany: introduced and indigenous food plants with a discussion of the historical and evolutionary development of India agriculture and agricultural systems in general. In: Renfrew JM (ed) New light on early farming. Edinburgh University Press, Edinburgh, UK, Recent Developments in Palaeoethnobotany, pp 155–189

    Google Scholar 

  • Kole C, Bode AO, Kole P, Rao VK, Bajpai A, Backiyarani S (2012) The first genetic map and positions of major fruit trait loci of bitter melon (Momordica charantia). J Plant Sci Mol Breed 1:1–6. https://doi.org/10.7243/2050-2389-1-1

    Article  CAS  Google Scholar 

  • Kole C, Kole P, Randunu KM, Choudhary P, Podila R, Ke PC, Rao AM, Marcus RK (2013) Nanobiotechnology can boost crop production and quality: first evidence from increased plant biomass, fruit yield and phytomedicine content in bitter melon (Momordica charantia). BMC Biotechnol 26(13):37. https://doi.org/10.1186/1472-6750-13-37

    Article  Google Scholar 

  • Marr KL, Xia YM, Bhattarai NK (2004) Allozyme, morphological and nutritional analysis bearing on the domestication of Momordica charantia L. (Cucurbitaceae). Econ Bot 58:435–455

    Article  Google Scholar 

  • Matsumura H, Miyagi N, Taniai N, Fukushima M, Tarora K, Shudo A (2014) Mapping of the gynoecy in bitter gourd (Momordica charantia) using RAD-Seq analysis. PLoS ONE 9:e87138. https://doi.org/10.1371/journal.pone.0087138

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Miniraj N, Prasanna KP, Peter KV (1993) Bitter gourd (Momordica spp.). In: Kalloo G, Bergh BO (eds) Genetic improvement of vegetable crops. Pergamon Press, Oxford, pp 239–246

    Google Scholar 

  • Ram D, Kumar S, Banerjee MK, Kalloo G (2002) Occurrence, identification and preliminary characterization of gynoecism in bitter gourd (Momordica charantia L.). Indian J Agri Sci 72:348–349

    Google Scholar 

  • Raman A, Lau C (1996) Anti-diabetic properties and phytochemistry of Momordica charantia L. (Cucurbitaceae). Phytomedicine 2:349–362

    Article  CAS  PubMed  Google Scholar 

  • Reyes MEC, Gildemacher BH, Jansen GJ (1994) Momordica L. In: Siemonsma JS, Piluek K (eds) Plant resources of South-East Asia: vegetables. Pudoc Scientific Publishers, Wageningen, the Netherlands, pp 206–210

    Google Scholar 

  • Roy SK (1973) A simple and rapid method for estimation of total carotenoids pigments in mango. J Food Sci Technol 10:45

    CAS  Google Scholar 

  • Sathishsekar D, Subramanian S (2005) Antioxidant properties of Momordica Charantia (bitter gourd) seeds on streptozotocin induced diabetic rats. Asia Pac J Clin Nutr 14(2):153–158

    PubMed  Google Scholar 

  • Semiz A, Sen A (2007) Antioxidant and chemoprotective properties of Momordica charantia L. (bitter melon) fruit extract. Afr J Biotechnol 6(3):273–277

    Google Scholar 

  • Singh AK, Behera TK, Chandel D, Sharma P, Singh NK (2007) Assessing genetic relationships among bitter gourd (Momordica charantia L.) accessions using inter simple sequence repeat (ISSR) markers. J Hort Sci Biotechnol 82:217–222

    Article  CAS  Google Scholar 

  • Sirohi PS (1997) Improvement in cucurbit vegetables. Indian Hort 42:64–67

    Google Scholar 

  • Tindall HD (1983) Vegetables in the tropics. Macmillan, London

    Book  Google Scholar 

  • Urasaki N, Takagi H, Natsume S, Uemura A, Taniai N, Miyagi N et al (2017) Draft genome sequence of bitter gourd (Momordica charantia), a vegetable and medicinal plant in tropical and subtropical regions. DNA Res 24(1):51–58. https://doi.org/10.1093/dnares/dsw047

    Article  CAS  PubMed  Google Scholar 

  • Walters TW, Decker-Walters DS (1988) Balsam-pear (Momordica charantia, Cucurbita- ceae). Econ Bot 42(2):286–292

    Article  Google Scholar 

  • Wang QM, Zeng GW (1997) Hormonal regulation of sex differentiation on Momordica charantia L. J Zhejiang Agri Univ 23:551–556

    CAS  Google Scholar 

  • Wang Z, Xiang C (2013) Genetic mapping of QTLs for horticulture traits in a F2-3 population of bitter gourd (Momordica charantia L.). Euphytica 193:235–250. https://doi.org/10.1007/s10681-013-0932-0

    Article  CAS  Google Scholar 

  • Yang SL, Walters TW (1992) Ethnobotany and the economic role of the Cucurbitaceae of China. Econ Bot 46:349–367

    Article  Google Scholar 

  • Yonemori S, Fujieda K (1985) Sex expression in Momordica charantia L. Sci Bull Coll Agri, Univ Ryukyus, Okinawa 32:183–187

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Chittaranjan Kole .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2020 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Behera, T.K., Matsumura, H., Kole, C. (2020). Glimpse on Genomics and Breeding in Bitter Gourd: A Crop of the Future for Food, Nutrition and Health Security. In: Kole, C., Matsumura, H., Behera, T. (eds) The Bitter Gourd Genome. Compendium of Plant Genomes. Springer, Cham. https://doi.org/10.1007/978-3-030-15062-4_1

Download citation

Publish with us

Policies and ethics