Abstract
To utilise MRI information to compliment CT in radiotherapy treatment planning, the MRI must be accurately registered to the CT. Image registration techniques used in the clinic can be either rigid or deformable; the difference between these are discussed in this chapter as well as examples of when it is clinically relevant to use them. Image registration algorithms are broken down into their constituent parts, and each component is explained.
Multimodal image registration is complicated and if used incorrectly can lead to treatment inaccuracies and incidents. Therefore accurate quality assurance (QA) of image registration software used in the clinic is vital. Image registration QA in the clinic is broken down into two stages. The first is commissioning of the system with the aim of evaluating the overall image registration process to ensure accurate registration can be consistently achieved. The second is verifying registration accuracy per patient with the aim of ensuring the registration is safe for that individual case. Techniques for performing QA are discussed and recommended procedures for both commissioning and verifying registration accuracy per patient are detailed.
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Acknowledgements
Dr. Richard Speight is supported by a Cancer Research UK Centres Network Accelerator Award Grant (A21993) to the ART-NET consortium. I would like to thank the editors of this book for the invitation to write this chapter. Ms. Robba Rai (Ingham Institute, Liverpool Cancer Centre, Sydney, Australia) is thanked for useful discussion on prostate fiducial marker registration. I would also like to thank my line manager (Dr. Bashar Al-Qaisieh) and my employer (Leeds Teaching Hospitals, Leeds, UK) for support in writing this chapter.
Finally I would also like to thank all those who read and provided comments and feedback on this chapter, particularly Mrs. Shona Whittam, Mr. David Bird and Dr. David Broadbent (all from Leeds Cancer Centre, Leeds, UK); Associate Professor Ann Henry and Dr. Katherine O’Mahony (University of Leeds, Leeds, UK); Dr. Robert Chuter and Mr. David Lines (both from The Christie NHS Foundation Trust, Manchester, UK); Dr. Jorge Cardoso (Kings Collage London, London, UK); Dr. Jamie McClelland (University College London, London, UK); and Dr. Ben George (CRUK/MRC Institute for Radiation Oncology, University of Oxford, UK).
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Speight, R. (2019). MRI to CT Image Registration. In: Liney, G., van der Heide, U. (eds) MRI for Radiotherapy. Springer, Cham. https://doi.org/10.1007/978-3-030-14442-5_2
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