Skip to main content

Recurrence of ROP After Anti-VEGF Treatment

  • Chapter
Pediatric Retinal Vascular Diseases

Abstract

This chapter is about recurrence of ROP after anti-VEGF treatment. The clinical course and timing of recurrence after anti-VEGF treatment is clarified. Furthermore, major clinical studies about the incidence of recurrence after anti-VEGF treatment for ROP are summarized.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 69.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 89.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 119.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Darwish D, Chee RI, Patel SN, Jonas K, Ostmo S, Campbell JP, Chiang MF, Chan RVP. Anti-Vascular endothelial growth factor and the evolving management paradigm for retinopathy of prematurity. Asia Pac J Ophthalmol (Phila). 2018;7:136–44.

    Google Scholar 

  2. Mintz-Hittner HA, Geloneck MM, Chuang AZ. Clinical management of recurrent retinopathy of prematurity after Intravitreal Bevacizumab monotherapy. Ophthalmology. 2016;123:1845–55.

    Article  Google Scholar 

  3. Snyder LL, Garcia-Gonzalez JM, Shapiro MJ, Blair MP. Very late reactivation of retinopathy of prematurity after monotherapy with Intravitreal Bevacizumab. Ophthalmic Surg Lasers Imaging Retina. 2016;47:280–3.

    Article  Google Scholar 

  4. Hajrasouliha AR, Garcia-Gonzales JM, Shapiro MJ, Yoon H, Blair MP. Reactivation of retinopathy of prematurity three years after treatment with Bevacizumab. Ophthalmic Surg Lasers Imaging Retina. 2017;48:255–9.

    Article  Google Scholar 

  5. Mintz-Hittner HA, Kennedy KA, Chuang AZ, BEAT-ROP Cooperative Group. Efficacy of intravitreal bevacizumab for stage 3+ retinopathy of prematurity. N Engl J Med. 2011;364:603–15.

    Article  CAS  Google Scholar 

  6. Wallace DK, Dean TW, Hartnett ME, Kong L, Smith LE, Hubbard GB, McGregor ML, Jordan CO, Mantagos IS, Bell EF, Kraker RT, Pediatric Eye Disease Investigator Group. A dosing study of Bevacizumab for retinopathy of prematurity: late recurrences and additional treatments. Ophthalmology. 2018;7 https://doi.org/10.1016/j.ophtha.2018.05.001.

  7. Chen SN, Lian I, Hwang YC, Chen YH, Chang YC, Lee KH, Chuang CC, Wu WC. Intravitreal anti-vascular endothelial growth factor treatment for retinopathy of prematurity: comparison between Ranibizumab and Bevacizumab. Retina. 2015;35:667–74.

    Article  CAS  Google Scholar 

  8. Gunay M, Sukgen EA, Celik G, Kocluk Y. Comparison of Bevacizumab, Ranibizumab, and laser photocoagulation in the treatment of retinopathy of prematurity in Turkey. Curr Eye Res. 2017;42:462–9.

    Article  CAS  Google Scholar 

  9. Stahl A, Krohne TU, Eter N, Oberacher-Velten I, Guthoff R, Meltendorf S, Ehrt O, Aisenbrey S, Roider J, Gerding H, Jandeck C, Smith LEH, Walz JM, Comparing Alternative Ranibizumab Dosages for Safety and Efficacy in Retinopathy of Prematurity (CARE-ROP) Study Group. Comparing alternative Ranibizumab dosages for safety and efficacy in retinopathy of prematurity: a randomized clinical trial. JAMA Pediatr. 2018;172:278–86.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this chapter

Cite this chapter

Spandau, U., Kim, S.J. (2019). Recurrence of ROP After Anti-VEGF Treatment. In: Pediatric Retinal Vascular Diseases. Springer, Cham. https://doi.org/10.1007/978-3-030-13701-4_19

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-13701-4_19

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-13700-7

  • Online ISBN: 978-3-030-13701-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics