Abstract
The objective of this chapter is to review the main biomechanical and structural aspects associated with both intrinsic and extrinsic skin ageing, and to present potential research avenues to account for these effects in mathematical and computational models of the skin. This will be illustrated through recent work of the authors which provides a basis to those interested in developing mechanistic constitutive models capturing the mechanobiology of skin across the life course.
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Acknowledgements
Part of this work was funded through the award of a Royal Society Newton Fund grant (2014–2016) between the Universities of Southampton and Cape Town. The authors would like to gratefully acknowledge this financial support as well as the logistic and infrastructure support provided by their respective institutions for research visits of Damien Pond, Andrew McBride and Georges Limbert. Georges Limbert would also like to thank Procter & Gamble and L´Oréal for their financial support of his research over the last few years.
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Limbert, G., Pond, D., McBride, A. (2019). Constitutive Modelling of Skin Ageing. In: Limbert, G. (eds) Skin Biophysics. Studies in Mechanobiology, Tissue Engineering and Biomaterials, vol 22. Springer, Cham. https://doi.org/10.1007/978-3-030-13279-8_5
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DOI: https://doi.org/10.1007/978-3-030-13279-8_5
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