Acute Treatment of Cluster Headache Attacks
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The treatment of acute cluster headache attacks is based on clinical trials and on empirical data. In the last decades, we also learnt more about the pathophysiology of cluster headache leading to new substances for both acute and prophylactic treatment. Although cluster headache is a very impressive somatic disorder, it has to be considered that drug treatment in cluster headache shows a placebo rate similar to that observed in migraine treatment . There are treatment guidelines available published for different parts of the world [2, 3], and the superiority of guideline-adherent treatment over purely intuitive treatment in cluster headache has been shown .
- 27.Silberstein SD, Mechtler LL, Kudrow DB, Calhoun AH, McClure C, Saper JR, Liebler EJ, Rubenstein Engel E, Tepper SJ, ACT1 Study Group. Non-invasive vagus nerve stimulation for the ACute Treatment of cluster headache: findings from the randomized, double-blind, sham-controlled ACT1 study. Headache. 2016;56:1317–32.CrossRefGoogle Scholar