Advertisement

Acute Treatment of Cluster Headache Attacks

  • Stefan EversEmail author
Chapter
First Online:
  • 430 Downloads
Part of the Headache book series (HEAD)

Abstract

The treatment of acute cluster headache attacks is based on clinical trials and on empirical data. In the last decades, we also learnt more about the pathophysiology of cluster headache leading to new substances for both acute and prophylactic treatment. Although cluster headache is a very impressive somatic disorder, it has to be considered that drug treatment in cluster headache shows a placebo rate similar to that observed in migraine treatment [1]. There are treatment guidelines available published for different parts of the world [2, 3], and the superiority of guideline-adherent treatment over purely intuitive treatment in cluster headache has been shown [4].

This is a preview of subscription content, log in to check access.

References

  1. 1.
    Nilsson-Remahl AI, Laudon Meyer E, Cordonnier C, Goadsby PJ. Placebo response in cluster headache trials: a review. Cephalalgia. 2003;23:504–10.CrossRefGoogle Scholar
  2. 2.
    May A, Leone M, Afra J, Linde M, Sandor PS, Evers S, Goadsby PJ. EFNS guidelines on the treatment of cluster headache and other trigeminal-autonomic cephalalgias. Eur J Neurol. 2006;13:1066–77.CrossRefGoogle Scholar
  3. 3.
    Robbins MS, Starling AJ, Pringsheim TM, Becker WJ, Schwedt TJ. Treatment of cluster headache: The American Headache Society evidence-based guidelines. Headache. 2016;56:1093–106.CrossRefGoogle Scholar
  4. 4.
    Lademann V, Jansen JP, Evers S, Frese A. Evaluation of guideline-adherent treatment in cluster headache. Cephalalgia. 2016;36:760–4.CrossRefGoogle Scholar
  5. 5.
    Janks JF. Oxygen for cluster headaches. JAMA. 1978;239:191.CrossRefGoogle Scholar
  6. 6.
    Fogan L. Treatment of cluster headache. A double-blind comparison of oxygen v air inhalation. Arch Neurol. 1985;42:362–3.CrossRefGoogle Scholar
  7. 7.
    Cohen AS, Burns B, Goadsby PJ. High-flow oxygen for treatment of cluster headache: a randomized trial. JAMA. 2009;302:2451–7.CrossRefGoogle Scholar
  8. 8.
    Petersen AS, Barloese MC, Lund NL, Jensen RH. Oxygen therapy for cluster headache. A mask comparison trial. A single-blinded, placebo-controlled, crossover study. Cephalalgia. 2017;37:214–24.CrossRefGoogle Scholar
  9. 9.
    Ekbom K, Monstad I, Prusinski A, Cole JA, Pilgrim AJ, Noronha D. Subcutaneous sumatriptan in the acute treatment of cluster headache: a dose comparison study. The Sumatriptan Cluster Headache Study Group. Acta Neurol Scand. 1993;88:63–9.CrossRefGoogle Scholar
  10. 10.
    The Sumatriptan Cluster Headache Study Group. Treatment of acute cluster headache with sumatriptan. N Engl J Med. 1991;325:322–6.CrossRefGoogle Scholar
  11. 11.
    Leone M, Proietti Cecchini A. Long-term use of daily sumatriptan injections in severe drug-resistant chronic cluster headache. Neurology. 2016;86:194–5.CrossRefGoogle Scholar
  12. 12.
    Gregor N, Schlesiger C, Akova-Oztürk E, Kraemer C, Husstedt IW, Evers S. Treatment of cluster headache attacks with less than 6 mg subcutaneous sumatriptan. Headache. 2005;45:1069–72.CrossRefGoogle Scholar
  13. 13.
    Cittadini E, May A, Straube A, Evers S, Bussone G, Goadsby PJ. Effectiveness of intranasal zolmitriptan in acute cluster headache: a randomized, placebo-controlled, double-blind crossover study. Arch Neurol. 2006;63:1537–42.CrossRefGoogle Scholar
  14. 14.
    Rapoport AM, Mathew NT, Silberstein SD, Dodick D, Tepper SJ, Sheftell FD, Bigal ME. Zolmitriptan nasal spray in the acute treatment of cluster headache: a double-blind study. Neurology. 2007;69:821–6.CrossRefGoogle Scholar
  15. 15.
    Schuh-Hofer S, Reuter U, Kinze S, Einhaupl KM, Arnold G. Treatment of acute cluster headache with 20 mg sumatriptan nasal spray - an open pilot study. J Neurol. 2002;249:94–9.CrossRefGoogle Scholar
  16. 16.
    Van Vliet JA, Bahra A, Martin V, Ramadan N, Aurora SK, Mathew NT, Ferrari MD, Goadsby PJ. Intranasal sumatriptan in cluster headache: randomized placebo-controlled double-blind study. Neurology. 2003;60:630–3.CrossRefGoogle Scholar
  17. 17.
    Bahra A, Gawel MJ, Hardebo JE, Millson D, Breen SA, Goadsby PJ. Oral zolmitriptan is effective in the acute treatment of cluster headache. Neurology. 2000;54:1832–9.CrossRefGoogle Scholar
  18. 18.
    Graham JR, Malvea BP, Gramm HF. Aerosol ergotamine tartrate for migraine and Horton’s syndrome. N Engl J Med. 1960;263:802–4.CrossRefGoogle Scholar
  19. 19.
    Andersson PG, Jespersen LT. Dihydroergotamine nasal spray in the treatment of attacks of cluster headache. Cephalalgia. 1986;6:51–4.CrossRefGoogle Scholar
  20. 20.
    Magnoux E, Zlotnik G. Outpatient intravenous dihydroergotamine for refractory cluster headache. Headache. 2004;44:249–55.CrossRefGoogle Scholar
  21. 21.
    Costa A, Pucci E, Antonaci F, Sances G, Granella F, Broich G, Nappi G. The effect of intranasal cocaine and lidocaine on nitroglycerin-induced attacks in cluster headache. Cephalalgia. 2000;20:85–91.CrossRefGoogle Scholar
  22. 22.
    Mills TM, Scoggin JA. Intranasal lidocaine for migraine and cluster headaches. Ann Pharmacother. 1997;31:914–5.CrossRefGoogle Scholar
  23. 23.
    Robbins L. Intranasal lidocaine for cluster headache. Headache. 1995;35:83–4.CrossRefGoogle Scholar
  24. 24.
    Matharu MS, Levy MJ, Meeran K, Goadsby PJ. Subcutaneous octreotide in cluster headache: randomized placebo-controlled double-blind crossover study. Ann Neurol. 2004;56:488–94.CrossRefGoogle Scholar
  25. 25.
    Paemeleire K, Bahra A, Evers S, Matharu MS, Goadsby PJ. Medication-overuse headache in patients with cluster headache. Neurology. 2006;67:109–13.CrossRefGoogle Scholar
  26. 26.
    Schoenen J, Jensen RH, Lantéri-Minet M, Láinez MJ, Gaul C, Goodman AM, Caparso A, May A. Stimulation of the sphenopalatine ganglion (SPG) for cluster headache treatment. Pathway CH-1: a randomized, sham-controlled study. Cephalalgia. 2013;33:816–30.CrossRefGoogle Scholar
  27. 27.
    Silberstein SD, Mechtler LL, Kudrow DB, Calhoun AH, McClure C, Saper JR, Liebler EJ, Rubenstein Engel E, Tepper SJ, ACT1 Study Group. Non-invasive vagus nerve stimulation for the ACute Treatment of cluster headache: findings from the randomized, double-blind, sham-controlled ACT1 study. Headache. 2016;56:1317–32.CrossRefGoogle Scholar
  28. 28.
    Gaul C, Diener HC, Silver N, Magis D, Reuter U, Andersson A, Liebler EJ, Straube A, PREVA Study Group. Non-invasive vagus nerve stimulation for PREVention and Acute treatment of chronic cluster headache (PREVA): a randomised controlled study. Cephalalgia. 2016;36:534–46.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  1. 1.Department of NeurologyKrankenhaus LindenbrunnCoppenbrüggeGermany

Personalised recommendations

Cite chapter

Buy options