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A Semantic-Wise Convolutional Neural Network Approach for 3-D Left Atrium Segmentation from Late Gadolinium Enhanced Magnetic Resonance Imaging

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Part of the book series: Lecture Notes in Computer Science ((LNIP,volume 11395))

Abstract

Several studies suggest that the assessment of viable left atrial (LA) tissue is a relevant information to support catheter ablation in atrial fibrillation (AF). Late gadolinium enhanced magnetic resonance imaging (LGE MRI) is a new emerging technique which is employed for the non-invasive quantification of LA fibrotic tissue. The analysis of LGE MRI relies on manual tracing of LA boundaries. This procedure is time-consuming and prone to high inter-observer variability given the different degrees of observers’ experience, LA wall thickness and data resolution. Therefore, an automatic approach for the LA wall detection would be highly desirable. This work focuses on the design and development of a semantic-wise convolutional neural network based on the successful architecture U-Net (U-SWCNN). Batch normalization, early stopping and parameter initializers consistent with the activation functions chosen were used; a loss function based on the Dice coefficient was employed. The U-SWCNN was trained end-to-end with the 3-D data available from the 2018 Atrial Segmentation Challenge. The training was completed using 80 LGE MRI data and a post-processing step based on the 3-D morphology was then applied. After the post-processing step, the average Dice coefficient on the validation set (20 LGE MRI data) was 0.911, while on the test set (54 LGE MRI data) was 0.898.

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Acknowledgement

Thanks to Dr. Marilisa Cortesi for lending the needed hardware. The experiments have been conducted using Keras [20] with TensorFlow [21] backend on CPU (Intel Xeon E5-2640) of a workstation equipped with 64 GB of RAM.

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Correspondence to Cristiana Corsi .

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Borra, D., Masci, A., Esposito, L., Andalò, A., Fabbri, C., Corsi, C. (2019). A Semantic-Wise Convolutional Neural Network Approach for 3-D Left Atrium Segmentation from Late Gadolinium Enhanced Magnetic Resonance Imaging. In: Pop, M., et al. Statistical Atlases and Computational Models of the Heart. Atrial Segmentation and LV Quantification Challenges. STACOM 2018. Lecture Notes in Computer Science(), vol 11395. Springer, Cham. https://doi.org/10.1007/978-3-030-12029-0_36

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  • DOI: https://doi.org/10.1007/978-3-030-12029-0_36

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-12028-3

  • Online ISBN: 978-3-030-12029-0

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