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Food-borne Trematodiases in East Asia: Epidemiology and Burden

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Neglected Tropical Diseases - East Asia

Part of the book series: Neglected Tropical Diseases ((NTD))

Abstract

Food-borne trematodiases are a cluster of parasitic helminth infections in humans and animals and belong to the cluster of neglected tropical diseases. The causative helminths dispose of a complex life cycle. As with many helminth infections, most infected people may only experience mild and non-specific clinical signs and symptoms. However, repeated, heavy and long-term infections may lead to severe clinical manifestations and also potentially fatal complications such as cholangiocarcinoma. Diagnosis remains a challenge as reliable, affordable, rapid, and simple-to-use diagnostic techniques are not available. If correctly and early diagnosed, safe, cheap, efficacious, orally administered drugs are available. Globally, the disease burden of food-borne trematodiases is estimated to be well within the range of other and better known neglected tropical diseases (e.g. dengue, leishmaniasis, lymphatic filariasis, onchocerciasis, and schistosomiasis) with a concentration in East and Southeast Asia. Food-borne trematodiases are zoonoses and may also have a negative impact on agri- and aquacultural production in affected regions. Mathematical modelling and analysis of food-borne trematodiases transmission dynamics to inform control and prevention is still in a very early stage, also due to the very limited availability of essential data. The current mainstay of human food-borne trematodiases control is drug-based morbidity control. For improved control, prevention or even elimination, more integrated efforts adopting also an ecosystem and “One Health” perspective are needed.

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Authors and Affiliations

  1. Centre for Health Policy, Imperial College London, London, UK

    Thomas Fürst

  2. Department of Infectious Disease Epidemiology, Imperial College London, London, UK

    Thomas Fürst

  3. Swiss Tropical and Public Health Institute, Basel, Switzerland

    Thomas Fürst, Peter Odermatt, Christine Bürli & Nakul Chitnis

  4. University of Basel, Basel, Switzerland

    Thomas Fürst, Peter Odermatt, Christine Bürli & Nakul Chitnis

  5. Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand

    Puangrat Yongvanit, Narong Khuntikeo & Paiboon Sithithaworn

  6. Cholangiocarcinoma Screening and Care Program, Khon Kaen University, Khon Kaen, Thailand

    Puangrat Yongvanit, Narong Khuntikeo & Paiboon Sithithaworn

  7. Department of Biochemistry, Khon Kaen University, Khon Kaen, Thailand

    Puangrat Yongvanit

  8. Department of Surgery, Khon Kaen University, Khon Kaen, Thailand

    Narong Khuntikeo

  9. Center for Parasitic Organisms, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat-Sen University, Guangzhou, People’s Republic of China

    Zhao-Rong Lun

  10. Department of Public Health, Erasmus University Medical Center, Rotterdam, The Netherlands

    Juanita A. Haagsma

  11. Section of Veterinary Epidemiology, University of Zürich, Zürich, Switzerland

    Paul R. Torgerson

  12. Department of Parasitology, Khon Kaen University, Khon Kaen, Thailand

    Paiboon Sithithaworn

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  1. Thomas Fürst
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  2. Puangrat Yongvanit
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  8. Christine Bürli
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  9. Nakul Chitnis
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  10. Paiboon Sithithaworn
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Corresponding author

Correspondence to Thomas Fürst .

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Editors and Affiliations

  1. Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland

    Jürg Utzinger

  2. Institute of Infectious Disease and Epidemiology, Tan Tock Seng Hospital, Singapore, Singapore

    Peiling Yap

  3. Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland

    Martin Bratschi

  4. Swiss Tropical and Public Health Institute and University of Basel, Basel, Switzerland

    Peter Steinmann

Ethics declarations

TF acknowledges financial support from the Swiss National Science Foundation (project no. P300P3-154634). PY, NK, and PS are supported by the National Research Council of Thailand through the Fluke Free Thailand Project. ZRL is supported by grants from the National Base Research programme (973 project; NO.2010CB530000) and the National Natural Science Foundation of China (project nos. #31272305 and #31472058). NC acknowledges funding from the RAPIDD program of the Science & Technology Directorate, Department of Homeland Security, and the Fogarty International Center, National Institutes of Health, USA.

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Fürst, T. et al. (2019). Food-borne Trematodiases in East Asia: Epidemiology and Burden. In: Utzinger, J., Yap, P., Bratschi, M., Steinmann, P. (eds) Neglected Tropical Diseases - East Asia. Neglected Tropical Diseases. Springer, Cham. https://doi.org/10.1007/978-3-030-12008-5_2

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