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Ischemic Heart Diseases

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Abstract

Cardiac magnetic resonance (CMR) is able to better characterize areas of the myocardium at risk, the presence and extent of myocardial fibrosis and myocardial viability and also to detect complications either in the setting of acute or chronic ischemic heart disease. CMR is multiparametric and offers the capability of a combined study of function, kinesis and myocardial tissue characterization. CMR has a better spatial resolution and capability of tissue characterization compared with other imaging techniques in the evaluation of ischemic heart disease. CMR is the gold standard for the evaluation of biventricular volumes and function and allows a better and more accurate study of wall motion abnormalities, localization and extent of myocardial scars as well as evaluation of the myocardium at risk (assessed by myocardial edema), late reperfusion (assessed by myocardial haemorrhage and MVO) and complications (thrombi, mechanical complications, RV involvement).

Stress CMR is a first-choice alternative for the evaluation of patients with suspected CAD and intermediate probability of disease as well as patients with known CAD and new symptoms. A complete protocol for the evaluation of a patient with ischemic heart disease includes cine sequences, STIR T2w imaging, stress perfusion (according to the clinical indication) and early and late gadolinium enhancement.

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References

  1. Dastidar AG, Rodrigues JC, Baritussio A, Bucciarelli-Ducci C. MRI in the assessment of ischaemic heart disease. Heart. 2016;102(3):239–52.

    Article  CAS  Google Scholar 

  2. McAlindon E, Pufulete M, Lawton C, Angelini GD, Bucciarelli-Ducci C. Quantification of infarct size and myocardium at risk: evaluation of different techniques and its implications. Eur Heart J Cardiovasc Imaging. 2015;16(7):738–46.

    Article  Google Scholar 

  3. Baritussio A, Scatteia A, Bucciarelli-Ducci C. Role of cardiovascular magnetic resonance in acute and chronic ischemic heart disease. Int J Cardiovasc Imaging. 2018;34(1):67–80.

    Article  CAS  Google Scholar 

  4. Aquaro GD, Di Bella G, Castelletti S, et al. Clinical recommendation of cardiac magnetic resonance, part I: ischemic and valvular heart disease: a position paper of the working group “Applicazioni della Risonanza Magnetica” of the Italian Society of Cardiology. J Cardiovasc Med. 2017;18:197–208.

    Article  Google Scholar 

  5. Hoffmann R, von Bardeleben S, Kasprzak JD, et al. Analysis of regional left ventricular function by cineventriculography, cardiac magnetic resonance imaging, and unenhanced and contrast-enhanced echocardiography: a multicenter comparison of methods. J Am Coll Cardiol. 2006;47:121–8.

    Article  Google Scholar 

  6. Aletras AH, Tilak GS, Natanzon A, et al. Retrospective determination of the area at risk for reperfused acute myocardial infarction with T2-weighted cardiac magnetic resonance imaging: histopathological and displacement encoding with stimulated echoes (DENSE) functional validations. Circulation. 2006;113(15):1865–70.

    Article  Google Scholar 

  7. Eitel I, Friedrich MG. T2-weighted cardiovascular magnetic resonance in acute cardiac disease. J Cardiovasc Magn Reson. 2011;13(1):13.

    Article  Google Scholar 

  8. Beek AM, van Rossum AC. Cardiovascular magnetic resonance imaging in patients with acute myocardial infarction. Heart. 2010;96:237–43.

    Article  Google Scholar 

  9. Husser O, Monmeneu JV, Sanchis J, et al. Cardiovascular magnetic resonance-derived intramyocardial hemorrhage after STEMI: influence on long-term prognosis, adverse left ventricular remodeling and relationship with microvascular obstruction. Int J Cardiol. 2013;167(5):2047–54.

    Article  Google Scholar 

  10. Romero J, Lupercio F, Carlos J, et al. Microvascular obstruction detected by cardiac MRI after AMI for the prediction of LV remodeling and MACE: a meta-analysis of prospective trials. Int J Cardiol. 2016;202:344–8.

    Article  Google Scholar 

  11. Kidambi A, Mather AN, Motwani M, Swoboda P, Uddin A, Greenwood JP, Plein S. The effect of microvascular obstruction and intramyocardial hemorrhage on contractile recovery in reperfused myocardial infarction: insights from cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2013;15:58.

    Article  Google Scholar 

  12. Flavian A, Carta F, Thuny F, et al. Cardiac MRI in the diagnosis of complications of myocardial infarction. Diagn Interv Imaging. 2012;93(7–8):578–85.

    Article  CAS  Google Scholar 

  13. Dastidar AG, Rodrigues JCL, Ahmed N, Baritussio A, Bucciarelli-Ducci C. The role of cardiac MRI in patients with troponin-positive chest pain and unobstructed coronary arteries. Curr Cardiovasc Imaging Rep. 2015;8(8):28.

    Article  Google Scholar 

  14. Tornvall P, Gerbaud E, Behaghel A, et al. Myocarditis or “true” infarction by cardiac magnetic resonance in patients with a clinical diagnosis of myocardial infarction without obstructive coronary disease: a meta-analysis of individual patient data. Atherosclerosis. 2015;241(1):87–91.

    Article  CAS  Google Scholar 

  15. Mahrholdt H, Wagner A, Judd RM, Sechtem U, Kim RJ. Delayed enhancement cardiovascular magnetic resonance assessment of non-ischaemic cardiomyopathies. Eur Heart J. 2005;26(15):1461–74.

    Article  Google Scholar 

  16. Motwani M, Swoboda PP, Plein S, Greenwood JP. Role of cardiovascular magnetic resonance in the management of patients with stable coronary artery disease. Heart. 2018;104(11):888–94. https://doi.org/10.1136/heartjnl-2017-311658.

    Article  CAS  PubMed  Google Scholar 

  17. Greenwood JP, Maredia N, Younger JF, et al. Cardiovascular magnetic resonance and single-photon emission computed tomography for diagnosis of coronary heart disease (CE-MARC): a prospective trial. Lancet. 2012;379:453–60.

    Article  Google Scholar 

  18. Schwitter J, Wacker CM, Wilke N, et al. Superior diagnostic performance of perfusion cardiovascular magnetic resonance versus SPECT to detect coronary artery disease: the secondary endpoints of the multicenter multivendor MR-IMPACT II (Magnetic Resonance Imaging for Myocardial Perfusion Assessment in Coronary Artery Disease Trial). J Cardiovasc Magn Reson. 2012;14:61.

    Article  Google Scholar 

  19. Jaarsma C, Leiner T, Bekkers SC, et al. Diagnostic performance of noninvasive myocardial perfusion imaging using single-photon emission computed tomography, cardiac magnetic resonance, and positron emission tomography imaging for the detection of obstructive coronary artery disease: a meta-analysis. J Am Coll Cardiol. 2012;59:1719–28.

    Article  Google Scholar 

  20. Li M, Zhou T, Yang LF, et al. Diagnostic accuracy of myocardial magnetic resonance perfusion to diagnose ischemic stenosis with fractional flow reserve as reference: systematic review and meta-analysis. JACC Cardiovasc Imaging. 2014;7:1098–105.

    Article  Google Scholar 

  21. Montalescot G, Sechtem U, Achenbach S, et al. 2013 ESC guidelines on the management of stable coronary artery disease: the task force on the management of stable coronary artery disease of the European Society of Cardiology. Eur Heart J. 2013;34:2949–3003.

    Article  Google Scholar 

  22. Fihn SD, Gardin JM, Abrams J, et al. 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. Circulation. 2012;126:e354–471.

    PubMed  Google Scholar 

  23. National Institute for Health and Care Excellence (NICE). CG95 Chest pain of recent onset 2016. http://guidance.nice.org.uk/CG95. Accessed Sep 2017.

  24. Greenwood JP, Ripley DP, Berry C, et al. Effect of care guided by cardiovascular magnetic resonance, myocardial perfusion scintigraphy, or nice guidelines on subsequent unnecessary angiography rates: the CE-MARC 2 randomized clinical trial. JAMA. 2016;316:1051–60.

    Article  Google Scholar 

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Authors and Affiliations

  1. Cardiovascular and Thoracic Department, AOU Città della Salute e della Scienza di Torino, University Cardiology, Turin, Italy

    Massimo Imazio & Monica Andriani

  2. Radiology Department, AOU Città della Salute e della Scienza di Torino, Turin, Italy

    Luisa Lobetti Bodoni

  3. Department of Medical Science, University of Turin, Turin, Italy

    Fiorenzo Gaita

Authors
  1. Massimo Imazio
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  2. Monica Andriani
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  3. Luisa Lobetti Bodoni
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  4. Fiorenzo Gaita
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Imazio, M., Andriani, M., Lobetti Bodoni, L., Gaita, F. (2019). Ischemic Heart Diseases. In: Learning Cardiac Magnetic Resonance . Springer, Cham. https://doi.org/10.1007/978-3-030-11608-8_4

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  • DOI: https://doi.org/10.1007/978-3-030-11608-8_4

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-11607-1

  • Online ISBN: 978-3-030-11608-8

  • eBook Packages: MedicineMedicine (R0)

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