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Cardiovascular and HIV Drug Interactions

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Cardiovascular Care in Patients With HIV

Abstract

Drug interactions with HIV medications are complex. When managing concurrent cardiovascular disease, statins, antiplatelets, anticoagulants, and antihypertensives are among select classes that are likely to lead to significant interactions. The greatest risk of drug interactions is associated with the use of cobicistat- or ritonavir-boosted HIV regimens. The lowest risk of drug interactions is associated with the use of raltegravir, dolutegravir, bictegravir, or rilpivirine-containing regimens. Providers are encouraged to use online databases for drug interaction screening when changing a medication used in managing cardiovascular disease or when altering any HIV regimen.

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Author information

Authors and Affiliations

  1. Department of Pharmacy, Albany Medical Center Hospital, Albany, NY, USA

    John J. Faragon

  2. Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California at San Diego, San Diego, CA, USA

    Nimish Patel

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  1. John J. Faragon
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  2. Nimish Patel
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Correspondence to John J. Faragon .

Editor information

Editors and Affiliations

  1. Bassett Research Institute, Bassett Medical Center, Cooperstown, NY, USA

    Merle Myerson

  2. Division of Infectious Diseases, Weill Cornell Medical College, New York, NY, USA

    Marshall J. Glesby

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Faragon, J.J., Patel, N. (2019). Cardiovascular and HIV Drug Interactions. In: Myerson, M., Glesby, M. (eds) Cardiovascular Care in Patients With HIV. Springer, Cham. https://doi.org/10.1007/978-3-030-10451-1_15

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  • DOI: https://doi.org/10.1007/978-3-030-10451-1_15

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-10450-4

  • Online ISBN: 978-3-030-10451-1

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