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Colorectal Cancer Surgical Emergencies in Patients with Inflammatory Bowel Disease

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Emergency Surgical Management of Colorectal Cancer

Part of the book series: Hot Topics in Acute Care Surgery and Trauma ((HTACST))

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Abstract

Inflammatory bowel diseases (IBDs) represent a well-known risk factor for the development of colorectal cancer. Even if screening programs are available for patients with IBDs to allow early detection of dysplastic and tumoral lesions, non-observant patients or those with no previous diagnosis of IBD may present with complex clinical scenarios of complicated colorectal cancer on IBD and may require emergency surgical treatment. The extent of the colitis, the gender (relative risk higher in males), the severity of inflammation (histological activity of the disease), a family history of sporadic colorectal cancer, and coexistent primary sclerosing cholangitis are risk factors for CRC in patients with IBDs. Complications of CRC requiring emergency management in patients with IBDs include bowel obstruction, colic perforation, or lower gastrointestinal bleeding. The emergency treatment of complications of CRC on IBD has three main objectives: treatment of the emergency condition, which may impact short-term prognosis, treatment of CRC, and management of IBD. The aim of this chapter is to discuss the incidence on colorectal cancer in IBDs patients, to examine the potential causes of emergency colorectal surgery in this setting, and to discuss treatment strategies in the light of the recent literature.

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Author information

Authors and Affiliations

  1. Service of Digestive, Hepato-Pancreato-Biliary Surgery and Liver Transplantation, Henri Mondor Hospital, AP-HP, Creteil, France

    Niccolò Petrucciani

  2. University of Paris Est, UPEC, Creteil, France

    Niccolò Petrucciani & Nicola de’Angelis

  3. Service of Digestive, Hepato-Pancreato-Biliary Surgery and Liver Transplantation, Unit of Minimally Invasive and Robotic Surgery, Henri Mondor Hospital, AP-HP, Créteil, France

    Nicola de’Angelis & Francesco Brunetti

  4. Gastroenterology and Endoscopy Unit, University Hospital of Parma, University of Parma, Parma, Italy

    Federica Gaiani

Authors
  1. Niccolò Petrucciani
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  2. Nicola de’Angelis
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  3. Federica Gaiani
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  4. Francesco Brunetti
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Corresponding author

Correspondence to Francesco Brunetti .

Editor information

Editors and Affiliations

  1. Department of General Surgery Unit of Digestive, Minimally Invasive and Robotic Surgery, Henri Mondor Hospital, Créteil, France

    Nicola de'Angelis

  2. Cambridge Colorectal Unit, Cambridge Biomedical Campus, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke’s Hospital, Cambridge, UK

    Salomone Di Saverio

  3. Department of General Surgery Unit of Digestive, Minimally Invasive and Robotic Surgery, Henri Mondor Hospital, Créteil, France

    Francesco Brunetti

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Petrucciani, N., de’Angelis, N., Gaiani, F., Brunetti, F. (2019). Colorectal Cancer Surgical Emergencies in Patients with Inflammatory Bowel Disease. In: de'Angelis, N., Di Saverio, S., Brunetti, F. (eds) Emergency Surgical Management of Colorectal Cancer. Hot Topics in Acute Care Surgery and Trauma. Springer, Cham. https://doi.org/10.1007/978-3-030-06225-5_18

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  • DOI: https://doi.org/10.1007/978-3-030-06225-5_18

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-06224-8

  • Online ISBN: 978-3-030-06225-5

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