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Medical and Surgical Management of Colorectal Cancer Patients Presenting with Haemostatic Disorders

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Emergency Surgical Management of Colorectal Cancer

Part of the book series: Hot Topics in Acute Care Surgery and Trauma ((HTACST))

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Abstract

Maintaining haemostasis during surgery is essential to preserve physiologic functions for the patient, provide the surgeon with the ability to see the operative field and promote successful wound management and patient outcomes. In addition, effective surgical haemostasis also results in fewer blood transfusions, decreased operating time and reduced morbidity and mortality.

The normal coagulation pathway represents a balance between the procoagulant pathway that is responsible for clot formation and the mechanisms that inhibit the same beyond the injury site. Imbalance of the coagulation system may occur in the perioperative period or during critical illness, which may be secondary to numerous factors leading to a tendency of either thrombosis or bleeding. A multidisciplinary approach is essential, and the surgical team must closely liaise with the haematology and anaesthetic team.

This chapter describes the pathophysiology of the haemostasis and the most common disorders encountered in clinical practice in emergency surgery.

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Author information

Authors and Affiliations

  1. Department of Colorectal Surgery, Queen Alexandra Hospital, Portsmouth Hospitals NHS Trust, Portsmouth, UK

    Valerio Celentano

  2. University of Portsmouth, Portsmouth, UK

    Valerio Celentano

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  1. Valerio Celentano
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Editor information

Editors and Affiliations

  1. Department of General Surgery Unit of Digestive, Minimally Invasive and Robotic Surgery, Henri Mondor Hospital, Créteil, France

    Nicola de'Angelis

  2. Cambridge Colorectal Unit, Cambridge Biomedical Campus, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke’s Hospital, Cambridge, UK

    Salomone Di Saverio

  3. Department of General Surgery Unit of Digestive, Minimally Invasive and Robotic Surgery, Henri Mondor Hospital, Créteil, France

    Francesco Brunetti

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Celentano, V. (2019). Medical and Surgical Management of Colorectal Cancer Patients Presenting with Haemostatic Disorders. In: de'Angelis, N., Di Saverio, S., Brunetti, F. (eds) Emergency Surgical Management of Colorectal Cancer. Hot Topics in Acute Care Surgery and Trauma. Springer, Cham. https://doi.org/10.1007/978-3-030-06225-5_15

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  • DOI: https://doi.org/10.1007/978-3-030-06225-5_15

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-06224-8

  • Online ISBN: 978-3-030-06225-5

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