• M. Altay Atalay


Candidiasis frequently occurs in newborns, in immune-deficient people like acquired immunodeficiency syndrome patients, and in people being treated with broad-spectrum antibiotics. It is manifested by the acute and/or chronic infections of the skin, mucosa, internal organs, and systems, which are caused by a genus of yeast called Candida species. It is mostly due to Candida albicans, while other species such as C. glabrata, C. parapsilosis, C. tropicalis, and C. krusei are increasingly isolated. Each of these organisms has unique virulence potential, antifungal susceptibility, and epidemiology. Recently, another species of Candida, C. auris, has been introduced, presenting with multidrug resistance and a high mortality rate as a dangerous health threat in some countries. Unlike superficial Candida infections, invasive candidiasis is an important healthcare-related infection that can affect the blood, heart, brain, eyes, bones, and other parts of the body.


Candidiasis Candida albicans Non-albicans Candida Superficial Candida infections Invasive candidiasis 



Acquired immunodeficiency syndrome


Chronic mucocutaneous candidiasis


Central nervous system or Coagulase-negative staphylococci


Cerebrospinal fluid


Computed tomography


Central venous catheter


Diabetes mellitus


European Society of Clinical Microbiology and Infectious Diseases


Gastrointestinal tract


Human immunodeficiency virus


Invasive candidiasis


Intensive care unit


Infectious Diseases Society of America




Magnetic resonance imaging


Non-albicans Candida


Negative predictive value


Positive predictive value


Total parenteral nutrition


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • M. Altay Atalay
    • 1
  1. 1.Department of Medical MicrobiologyErciyes University School of MedicineKayseriTurkey

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