Abstract
Acute kidney injury (AKI) is very common during critical illness affecting >50% of patients and associated with increased morbidity and mortality and high health care costs [1]. The traditional strategy for managing patients at risk or with established AKI often involves high volume fluid administration due to fear of untreated hypovolemia [2]. Whilst timely fluid administration may be beneficial if AKI is indeed precipitated by intravascular volume depletion, there is increasing evidence that excessive fluid resuscitation beyond correction of hypovolemia leads to adverse outcomes, including worsening of renal function [3–6]. Furthermore, there is clear evidence that certain types of fluids are nephrotoxic [3, 6–9].
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Ostermann, M., More, A., Jog, S. (2019). Fluid Management in Acute Kidney Injury. In: Vincent, JL. (eds) Annual Update in Intensive Care and Emergency Medicine 2019. Annual Update in Intensive Care and Emergency Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-06067-1_24
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DOI: https://doi.org/10.1007/978-3-030-06067-1_24
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