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Clinical Ophthalmic Oncology pp 45–52Cite as

Squamous Cell Carcinoma

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Abstract

Squamous cell carcinoma (SCC) is a malignancy that arises from the prickle–squamous cell layers of the epithelium. It can metastasize to regional lymph nodes and is potentially fatal. Most patients with SCC are 60 years of age or older. The main risk factors include ultraviolet light and actinic damage. Because of its variable clinical presentation, biopsy and histological examination are required for an accurate diagnosis. The main treatment modality is surgical excision, with microscopic monitoring of the margins or Mohs’ microsurgery. The treatment of choice for secondary orbital invasion is orbital exenteration. Keratoacanthoma is considered to be a variant of SCC.

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Author information

Authors and Affiliations

  1. Department of Ophthalmology, Eye Histopathology Laboratory, Goldschleger Eye Institute, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

    Mordechai Rosner

  2. Department of Ophthalmology, Ocular Oncology Center, Goldschleger Eye Institute, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

    Ido Didi Fabian

Authors
  1. Mordechai Rosner
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  2. Ido Didi Fabian
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Editor information

Editors and Affiliations

  1. Ocular Onocology Service and Ophthalmic Pathology Laboratory, Department of Ophthalmology, Hadassah - Hebrew University Medical Center, Jerusalem, Israel

    Jacob Pe'er

  2. Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA

    Arun D. Singh

  3. Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK

    Bertil E. Damato

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Rosner, M., Fabian, I.D. (2019). Squamous Cell Carcinoma. In: Pe'er, J., Singh, A., Damato, B. (eds) Clinical Ophthalmic Oncology. Springer, Cham. https://doi.org/10.1007/978-3-030-06046-6_5

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  • DOI: https://doi.org/10.1007/978-3-030-06046-6_5

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-06045-9

  • Online ISBN: 978-3-030-06046-6

  • eBook Packages: MedicineMedicine (R0)

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