Skip to main content

Caruncle Tumors

  • Chapter
  • First Online:
  • 499 Accesses

Abstract

Caruncular lesions are rare but can present a clinical challenge because of the wide variety of lesions that can arise in this complex structure, also most of the clinical features can overlap between distinct entities. The vast majority of the caruncle lesions are benign, and of these, the most common are nevus or epithelial origin lesions. Malignant lesions arising from the caruncle tend to have a worst prognosis from their conjunctival counterparts because of their close proximity to adjacent structures or their intimate relation to the orbit. Biopsy should be done in all caruncle lesions if malignancy is suspected.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD   139.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  1. Spencer W. Ophthalmic pathology: an atlas and textbook, vol. 1. 4th ed: Saunders: Philadelphia; 1996.

    Google Scholar 

  2. Kathuria SS, Howarth D, Hurwitz JJ, et al. An anatomic and histologic study of the caruncle. Ophthal Plast Reconstr Surg. 1999;15(6):407–11.

    Article  CAS  Google Scholar 

  3. Mori M. The structure of the caruncula lacrimalis of Japanese. Okajimas Folia Anat Jpn. 1965;41(5):277–83.

    Article  CAS  Google Scholar 

  4. Kaeser PF, Uffer S, Zografos L, et al. Tumors of the caruncle: a clinicopathologic correlation. Am J Ophthalmol. 2006;142(3):448–55.

    Article  Google Scholar 

  5. Luthra CL, Doxanas MT, Green WR. Lesions of the caruncle: a clinicohistopathologic study. Surv Ophthalmol. 1978;23(3):183–95.

    Article  CAS  Google Scholar 

  6. Santos A, Gómez-Leal A. Lesions of the lacrimal caruncle. Clinicopathologic features. Ophthalmology. 1994;101(5):943–9.

    Article  CAS  Google Scholar 

  7. Shields CL, Shields JA, White D, et al. Types and frequency of lesions of the caruncle. Am J Ophthalmol. 1986;102(6):771–8.

    Article  CAS  Google Scholar 

  8. Levy J, Ilsar M, Deckel Y, et al. Lesions of the caruncle: a description of 42 cases and a review of the literature. Eye (Lond). 2009;23(5):1004–18.

    Article  CAS  Google Scholar 

  9. Ostergaard J, Prause J, Heegard S. Caruncular lesions in Denmark 1978–2002: a histopathological study with correlation to clinical referral diagnosis. Acta Ophthalmol Scand. 2006;84:130–6.

    Article  Google Scholar 

  10. Solari HP, Ventura MP, Orellana ME, et al. Histopathological study of lesions of the caruncle: a 15-year single center review. Diagn Pathol. 2009;4:29.

    Article  Google Scholar 

  11. Von Graefes A. Geschwulste der Tranenkarunkel. Archiv fur Ophthalmologie. 1854;1:289–91.

    Google Scholar 

  12. Sjö NC, Heegaard S, Prause JU, et al. Human papillomavirus in conjunctival papilloma. Br J Ophthalmol. 2001;85(7):785–7.

    Article  Google Scholar 

  13. Eagle R. Eye pathology and atlas and text. 2nd ed. Lippincot Willims and Wilkins/Wolters Kluwer: Philladelphia; 2011.

    Google Scholar 

  14. Ogawa M, Shinzawa M, Dogru M, et al. Caruncular and pericaruncular sebaceous gland hyperplasia: a report of 2 cases and literature review. Eye Contact Lens. 2016;44(Suppl 1):S316–9.

    Google Scholar 

  15. Kapil JP, Proia AD, Puri PK. Lesions of the lacrimal caruncle with an emphasis on oncocytoma. Am J Dermatopathol. 2011;33(3):227–35.

    Article  Google Scholar 

  16. Shields JA, Shields CL, Marr BP, et al. Sebaceous carcinoma of the caruncle. Cornea. 2006;25(7):858–9.

    Article  Google Scholar 

  17. Pfeiffer ML, Yin VT, Myers J, et al. Regional nodal recurrence of sebaceous carcinoma of the caruncle 11 years after primary tumor resection. JAMA Ophthalmol. 2013;131(8):1091–2.

    Article  Google Scholar 

  18. Ugurlu S, Ekin MA, Altinboga AA. Primary basal cell carcinoma of the caruncle: case report and review of the literature. Ophthal Plast Reconstr Surg. 2014;30(3):e62–4.

    PubMed  Google Scholar 

  19. Shields CL, Fasiuddin AF, Mashayekhi A, et al. Conjunctival nevi: clinical features and natural course in 410 consecutive patients. Arch Ophthalmol. 2004;122(2):167–75.

    Article  Google Scholar 

  20. Ozdal PC, Kargi S, Göka S, et al. Capillary hemangioma of the caruncle. Can J Ophthalmol. 2004;39(5):560–2.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Hans E. Grossniklaus .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this chapter

Check for updates. Verify currency and authenticity via CrossMark

Cite this chapter

Grossniklaus, H.E., Capiz-Correa, D.R., Wells, J.R. (2019). Caruncle Tumors. In: Pe'er, J., Singh, A., Damato, B. (eds) Clinical Ophthalmic Oncology. Springer, Cham. https://doi.org/10.1007/978-3-030-06046-6_19

Download citation

  • DOI: https://doi.org/10.1007/978-3-030-06046-6_19

  • Published:

  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-06045-9

  • Online ISBN: 978-3-030-06046-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics