Addressing Key Knowledge Gaps in Nutrition Research and the Impact of Funding Priorities in Human Nutrition

  • La Verne L. BrownEmail author
  • Paul M. Coates
Part of the Nutrition and Health book series (NH)


An improved nutritional status is believed to be a cost-effective strategy for reducing mortality, morbidity, and risks of chronic diseases. However, much of the scientific evidence to support the benefits of nutrients for health maintenance lack consistency and validity. Study designs, methodologies, tools, and funding priorities for nutrition research are evolving to better address key knowledge gaps impacting the science. Some examples include (1) development of new tools to improve assessments of dietary intake, (2) identification and validation of improved biomarkers for determining nutrition status, (3) enhancement of omics technologies to better map the interrelationships between intake (via supplement or food) and true nutrient bioavailability, and (4) improved study designs to better address phenotypic variations in nutrient requirements. To adequately address these and other knowledge gaps, funding opportunities have expanded beyond isolated federal agency initiatives to include more interagency collaborations, public-private partnerships, and international collaborations. The broader scope of collaborations is expected to promote greater opportunities for nutrition researchers to participate in the sharing and analysis of biomedical big data. Capitalizing on access to and the use of biomedical big data may facilitate investigations of the full complexities of the human ecosystem with respect to the nutrition sciences. Provided here is an overview of the funding priorities and trends as they relate to the key knowledge gaps impacting nutrition sciences to date.


Nutrient status Dietary intake Bioavailability Phenotype variations Food synergy Nutrient-nutrient interactions Nutrition assessments Government funding Public-private partnerships International collaborations 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Office of Dietary SupplementsNational Institutes of HealthBethesdaUSA

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