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Nutraceuticals in Mastitis

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Nutraceuticals in Veterinary Medicine

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Abstract

Acute and chronic forms of mastitis are the costliest disease in the dairy industry. Resistance of microbial pathogens to antimicrobials approved for clinical use is a significant threat to controlling mastitic pathogens and is a public health issue. In some countries, the cost of antimicrobial drugs reduces their usage, and ethnic remedies are being used. Organic dairies have prioritized the maintenance of mammary health and the use of nutraceuticals to prevent and treat mastitis. In some jurisdictions, dairy animals on organic farms that receive antibiotics are disqualified for life as dairy animals. There is conflicting evidence on the efficacy of nutraceuticals, homeopathy, and traditional medicine in treating mastitis and a lack of standards for evaluation of these remedies. Studies are showing that nutraceuticals can be efficacious. Phytotherapeutics generally are complex chemical mixtures and can be multifaceted in mechanisms of action. Intramammary infusions of probiotics and bacteriocins are being shown to be efficacious, and their mechanisms of action include being an immune stimulant. Immunotherapy with antibodies and immune system components can be efficacious. Intermingled treatments with nutraceuticals and pharmaceuticals can be more efficacious than either treatment alone.

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Notes

  1. 1.

    Eco-Mast, 10 mL/tube, Daehan New Pharm (Seoul, South Korea)

  2. 2.

    Daesung Gentamicin Cream, Daesung Microbiological Labs (Seoul, South Korea)

  3. 3.

    The bovine udder has four distinct mammary glands with each gland draining into one teat.

  4. 4.

    25 mg cefoperazone/mL, Mastiwock, Wockhardt Laboratories (Mumbai, India)

  5. 5.

    Dahua Traditional Chinese Medicine Company (Nanjing, Jiangsu Province)

  6. 6.

    Sigma-Aldrich

  7. 7.

    Sigma-Aldrich

  8. 8.

    Control of Pharmaceutical and Biological Product (Beijing, China)

  9. 9.

    Gentamicin Cream, Daesung Microbiological Labs (Korea)

  10. 10.

    Eco-Mast 10 mL/tube containing 0.9 mL oregano oil, Daehan New Pharm (Korea)

  11. 11.

    Sigma-Aldrich Chemical Co. (St Louis, MO)

  12. 12.

    Mastilep, Dabur Ayurvet Ltd. (Ghaziabad, India)

  13. 13.

    Indena®, SpA (Milan, Italy)

  14. 14.

    Indena SpA (Milan, Italy)

  15. 15.

    Phyto-Mast®, Penn Dutch Cow Care (Narvon, PA)

  16. 16.

    Ralco Animal Health (Marshall, MN, USA)

  17. 17.

    Cayenne, echinacea, and garlic (Arcadia, WI, USA)

  18. 18.

    https://www.dsm.com

  19. 19.

    https://www.charm.com

  20. 20.

    Quartermaster, Zoetis (Florham Park, NJ)

  21. 21.

    Orbeseal, Zoetis (Florham Park, NJ)

  22. 22.

    New AgriTech Enterprises (Locke, NY)

  23. 23.

    http://newagritech.com/

  24. 24.

    Steingassner HM (1998) Homoopathische Materia Medica fur Veterinarmediziner (Wien: Wilhelm Maudrich, Vienna)

  25. 25.

    Criteria of International Dairy Federation (Brussels, Belgium)

  26. 26.

    BCCM/LMG Bacteria Collection (Belgium)

  27. 27.

    Synulox, Pfizer Animal Health (New York, USA)

  28. 28.

    Zhejiang Silver-Elephant Bioengineering Co., Ltd. (Tiantai, Zhejiang, China)

  29. 29.

    Jilin Animal Health Products Co., Ltd. (Jilin, China)

  30. 30.

    Zhejiang Silver-Elephant Bio-Engineering Co., Ltd. (Tiantai, China)

  31. 31.

    Omu Milk Products Co., Ltd. (Fukuoka, Japan)

  32. 32.

    Meiji Seika Pharma Co., Ltd. (Tokyo, Japan)

  33. 33.

    Multimin 90, Multimin North America Inc. (Fort Collins, CO)

  34. 34.

    Natur-E granulat 40%, Pharmalett A/S (Kolding, Denmark)

  35. 35.

    Dipal Concentrate 1C4 (Delaval, Tianjin, China)

  36. 36.

    SunSmile® Fruit & Vegetable Rinse (Sunrider International, http://www.sunrider.com/eng/worldwide/offices#)

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Authors and Affiliations

  1. Toxicologist and Assoc Ltd, Vegreville, AB, Canada

    Robert W. Coppock

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  1. Robert W. Coppock
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Correspondence to Robert W. Coppock .

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Editors and Affiliations

  1. Department of Toxicology, Breathitt Veterinary Center, Murray State University, Hopkinsville, KY, USA

    Ramesh C. Gupta

  2. Vets Plus Inc., University of Wisconsin–Stout, Menonomie, WI, USA

    Ajay Srivastava

  3. Vets Plus Inc., Menomonie, WI, USA

    Rajiv Lall

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Coppock, R.W. (2019). Nutraceuticals in Mastitis. In: Gupta, R., Srivastava, A., Lall, R. (eds) Nutraceuticals in Veterinary Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-04624-8_38

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