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International Conference on Smart Vehicular Technology, Transportation, Communication and Applications

VTCA 2018: Advances in Smart Vehicular Technology, Transportation, Communication and Applications pp 394–401Cite as

Brain Structural Abnormalities in Reward and Emotion System in Internet Addiction Disorder

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Part of the book series: Smart Innovation, Systems and Technologies ((SIST,volume 129))

Abstract

Internet addiction disorder (IAD) is increasingly recognized as a mental health disorder, particularly among adolescents. The pathogenesis associated with IAD, however, remains unclear. This study aims to explore the changed structural characteristics of IAD adolescents at rest. We recruited 11 adolescents who meet the criteria as IAD group and 11 age and gender matched university students seldom use Internet as Healthy control (HC) group. High-resolution T1- weighted magnetic resonance imaging scans were performed on the two groups. Voxel-based morphometry (VBM) analysis was used to compare the gray matter density (GMD) between the two groups. In addition, a correlation analysis was performed to assess the relationships between GMD of abnormal brain regions and clinical internet addiction measure. Compared with healthy controls, IAD had lower GMD in the amygdala, middle temporal gyrus (MTG), middle occipital gyrus (MOG), orbital frontal cortex (OFC), middle frontal cortex (MFC), anterior cingulate cortex (ACC), thalamus, olfactory, putamen and caudate and the GMD of thalamus has a negative correlation with the Internet Addiction Test (IAT) scores. Our findings suggested that brain structural changes of IAD present weakened characteristics of IAD in two systems: reward system and emotion regulation system, and this finding may provide a new insight into the pathogenesis of IAD.

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Acknowledgment

This work is supported by the National Natural Science Foundation of China (Grant No. 61105117, 61472058, 61772102).

Author information

Authors and Affiliations

  1. School of Information, Dalian Maritime University, Dalian, China

    Jinqing Yang, Zhongyuan Cao, Shigang Feng, Hongbo Liu & Mingyu Lu

  2. Physical Science and Technical College, Dalian University, Dalian, China

    Wei Wang

  3. Affiliated Xinhua Hospital, Dalian University, Dalian, China

    Zhaobin Deng & Wencai Weng

Authors
  1. Jinqing Yang
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  2. Wei Wang
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  3. Zhongyuan Cao
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  4. Zhaobin Deng
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  5. Wencai Weng
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  6. Shigang Feng
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  7. Hongbo Liu
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  8. Mingyu Lu
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Corresponding author

Correspondence to Shigang Feng .

Editor information

Editors and Affiliations

  1. School of Transportation and Logistics, Southwest Jiaotong University, Chengdu, Sichuan, China

    Shaoquan Ni

  2. College of Information Science and Engineering, Fujian University of Technology, Fuzhou, Fujian, China

    Tsu-Yang Wu

  3. School of Transportation, Fujian University of Technology, Fuzhou, Fujian, China

    Tang-Hsien Chang

  4. College of Information Science and Engineering, Fujian University of Technology, Fuzhou, Fujian, China

    Jeng-Shyang Pan

  5. University of Technology Sydney, Sydney, NSW, Australia

    Lakhmi C. Jain

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Yang, J. et al. (2019). Brain Structural Abnormalities in Reward and Emotion System in Internet Addiction Disorder. In: Ni, S., Wu, TY., Chang, TH., Pan, JS., Jain, L. (eds) Advances in Smart Vehicular Technology, Transportation, Communication and Applications. VTCA 2018. Smart Innovation, Systems and Technologies, vol 129. Springer, Cham. https://doi.org/10.1007/978-3-030-04582-1_46

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