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Pyroelectric Sensor for Characterization of Biological Cells

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Sensors (CNS 2018)

Part of the book series: Lecture Notes in Electrical Engineering ((LNEE,volume 539))

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Abstract

Nowadays, cell characterization represents a fundamental task widely diffused in different fields. The main purpose of this paper is the design and development of a device for cellular characterization based on a pyroelectric sensor. After a brief introduction dedicated to the methods actually employed for cell counting, the pyroelectric sensor, the electronic readout unit, and the prototype will be introduced. Different cell concentration samples have been analyzed in order to highlight how the induced pyroelectric response is related to the cell properties. Experimental results shown that sensor output is strongly affected by cell type, concentration and viability. Particularly, it has been observed an increase in output signal related to an increase in cell concentration, mainly due to a lower thermal conductivity. No significant variation has been observed by the drastic reduction of cell viability also by varying cell concentration. The aforementioned results are probably due to the induction of a decrease in mitochondrial activity. Obtained results are very promising for the realization of a low cost laboratory device with all the characteristics listed above.

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Author information

Authors and Affiliations

  1. Department of Health Sciences, University Magna Græcia of Catanzaro, Viale Europa, 88100, Catanzaro, Italy

    S. A. Pullano, M. Greco, D. M. Corigliano, D. P. Foti, A. Brunetti & A. S. Fiorillo

Authors
  1. S. A. Pullano
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  2. M. Greco
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  3. D. M. Corigliano
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  4. D. P. Foti
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  5. A. Brunetti
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  6. A. S. Fiorillo
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Corresponding author

Correspondence to S. A. Pullano .

Editor information

Editors and Affiliations

  1. University of Catania, Catania, Italy

    Bruno Andò

  2. IFAC-CNR, Sesto Fiorentino, Florence, Italy

    Francesco Baldini

  3. University of Rome Tor Vergata, Rome, Italy

    Corrado Di Natale

  4. Department of Information Engineering (DII), University of Brescia, Brescia, Italy

    Vittorio Ferrari

  5. University of Catania, Catania, Italy

    Vincenzo Marletta

  6. Department of Chemistry, University of Florence, Sesto Fiorentino, Florence, Italy

    Giovanna Marrazza

  7. University of Palermo, Palermo, Italy

    Valeria Militello

  8. University of Padova, Padua, Italy

    Giorgia Miolo

  9. Sapienza University of Rome, Rome, Italy

    Marco Rossi

  10. Università Politecnica delle Marche (UNIVPM), Ancona, Italy

    Lorenzo Scalise

  11. IMM-CNR, Lecce, Italy

    Pietro Siciliano

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Pullano, S.A., Greco, M., Corigliano, D.M., Foti, D.P., Brunetti, A., Fiorillo, A.S. (2019). Pyroelectric Sensor for Characterization of Biological Cells. In: Andò, B., et al. Sensors. CNS 2018. Lecture Notes in Electrical Engineering, vol 539. Springer, Cham. https://doi.org/10.1007/978-3-030-04324-7_29

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  • DOI: https://doi.org/10.1007/978-3-030-04324-7_29

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-030-04323-0

  • Online ISBN: 978-3-030-04324-7

  • eBook Packages: EngineeringEngineering (R0)

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