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Neurotropic Viruses

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Defense Against Biological Attacks

Abstract

Neurotropic viruses can cause rapidly progressing and potentially devastating disease. In this chapter, predominant enveloped RNA viruses that can induce neurological disease are discussed. Some of these viruses, such as alphaviruses and flaviviruses, are transmitted by the bite of an arthropod. Others are transmitted through direct contact with infected animals or their excreta. While several of these viruses have been explored as potential bioweapons, the potential for such an application is limited by the technical ability to generate sufficient virus stocks and the poor transmissibility of these viruses. Also discussed are existing or potential medical countermeasures for the treatment or prevention of infection.

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  1. NIAID Integrated Research Facility, Frederick, MD, USA

    Michael R. Holbrook

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  1. Michael R. Holbrook
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Editors and Affiliations

  1. Molecular Biology Unit, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India

    Sunit K. Singh

  2. NIH/NIAID, Division of Clinical Research, Integrated Research Facility at Fort Detrick, Frederick, MD, USA

    Jens H. Kuhn

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Holbrook, M.R. (2019). Neurotropic Viruses. In: Singh, S., Kuhn, J. (eds) Defense Against Biological Attacks. Springer, Cham. https://doi.org/10.1007/978-3-030-03071-1_1

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