Abstract
Following a recent diagnosis of breast carcinoma, a 33-year-old, G2, P2 woman was referred by her surgeon for discussion of potential effects of cancer therapy on future reproductive function and fertility preservation. She had noted a lump in her left breast 3 months prior and was referred to the rapid breast cancer clinic for evaluation. Mammogram and ultrasound confirmed a 4 cm suspicious left upper quadrant lesion in the left breast. Lymph nodes appeared benign clinically and by imaging. Ultrasound-guided needle biopsy and rapid pathology confirmed grade lll invasive ductal carcinoma, focally suspicious for lymphovascular tumor emboli. She was simultaneously referred to medical oncology and the fertility clinic on the day after biopsy, when pathology confirmed malignancy.
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Lambertini M, Kroman N, Ameye L, Cordoba O, Pinto A, Benedetti G, Jensen MB, Gelber SI, Del Grande M, Ignatiadis M, De Azambuja E, Paesmans M, Peccatori F, Azim HA Jr. J Clin Oncol. 2017;35:18_suppl, LBA10066-LBA10066
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Q1.
If a patient already has children, is it worthwhile to refer her for a fertility preservation consultation?
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A1.
As per ASCO [8], the possible effect of cancer treatment on future fertility must be discussed with all patients of reproductive age and appropriate referral to a fertility preservation team offered.
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Q2.
What categories of medications are used to reduce estrogen exposure in stimulation cycles in patients with hormone-sensitive tumors?
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Greenblatt, E.M., McMahon, E., Cil, T.D. (2019). Oncofertility Case Study: Breast Cancer in a 33-Year-Old Woman. In: Woodruff, T., Shah, D., Vitek, W. (eds) Textbook of Oncofertility Research and Practice. Springer, Cham. https://doi.org/10.1007/978-3-030-02868-8_40
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DOI: https://doi.org/10.1007/978-3-030-02868-8_40
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