Abstract
This study involved the collection of clinical practice guidelines ( s) on five noncommunicable disease (NCD) areas from 21 European countries, and extraction of their evidence base in the form of papers in journals processed on the Web of Science ( ). We analyzed these cited papers to see how their geographical provenance compared with European research in the respective subjects and found that European research (and that from the USA, Australia, and New Zealand) was over-cited compared with that from East Asia. In cancer, surgery and radiotherapy research made important contributions to the CPGs.
We also collected medical research stories from 30 newspapers from 22 European countries and the WoS papers that they cited. There was a heavy emphasis on cancer, particularly breast cancer, and its epidemiology, genetics, and prognosis, but new treatment methods were seldomly reported, particularly surgery and radiotherapy. Some of the stories quoted commentators, with those from the two UK newspapers often mentioning medical research charities, which thereby gained much free publicity.
Both sets of cited research papers showed a marked tendency to be over-cited by documents from their countrymen; the ratio was higher the smaller the country's contribution to research in the subject area.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
S.R. Hanney, M.A. González-Block: Health research improves healthcare: Now we have the evidence and the chance to help the WHO spread such benefits globally, Health Res. Policy Syst. 13(1), 12 (2015)
D.M. Cutler, S. Kadiyala: The return to biomedical research: Treatment and behavioral effects. In: Measuring the Gains from Medical Research: An Economic Approach, ed. by K.M. Murphy, R.H. Topel (Univ. of Chicago Press, Chicago 2003) pp. 110–119
M.R. Macleod, S. Michie, I. Roberts, U. Dirnagl, I. Chalmers, J.P. Ioannidis, R.A.S. Salman, A.W. Chan, P. Glasziou: Biomedical research: Increasing value, reducing waste, Lancet 383(9912), 101–104 (2014)
R. Grol, J. Grimshaw: From best evidence to best practice: Effective implementation of change in patients' care, Lancet 362(9391), 1225–1230 (2003)
D.L. Sackett: Evidence-based medicine, Semin. Perinatol. 21(1), 3–5 (1997)
O.M. Al-Quteimat, A.M. Amer: Evidence-based pharmaceutical care: The next chapter in pharmacy practice, Saudi Pharm. J. 24(4), 447–451 (2016)
J.R. Hampton: Evidence-based medicine, opinion-based medicine, and real-world medicine, Perspect. Biol. Med. 45(4), 549–568 (2002)
I. Skoglund, K. Segesten, C. Björkelund: GPs' thoughts on prescribing medication and evidence-based knowledge: The benefit aspect is a strong motivator: A descriptive focus group study, Scand. J. Prim. Health Care 25(2), 98–104 (2007)
S. Every-Palmer, J. Howick: How evidence-based medicine is failing due to biased trials and selective publication, J. Eval. Clin. Pract. 20(6), 908–914 (2014)
D. Blumenthal: Doctors and drug companies, N. Engl. J. Med. 351(18), 1885–1890 (2004)
J. Abraham: Science, Politics and the Pharmaceutical Industry: Controversy and Bias in Drug Regulation (UCL, London 1995)
J. Hewitt-Taylor: Clinical practice guidelines and care protocols, Intensive Crit. Care Nurs. 20(1), 45–52 (2004)
R. Grilli, C. Ramsay, S. Minozzi: Mass media interventions: Effects on health services utilisation, Cochrane Libr. (2002), https://doi.org/10.1002/14651858.CD000389
J.B. McKinlay: The promotion of health through planned sociopolitical change: Challenges for research and policy, Soc. Sci. Med. 36(2), 109–117 (1993)
O.A. Arah: On the relationship between individual and population health, Med. Health Care Philos. 12(3), 235–244 (2009)
A. Antonovsky: The salutogenic model as a theory to guide health promotion, Health Promot. Int. 11(1), 11–18 (1996)
R.C. Brownson, J.F. Chriqui, K.A. Stamatakis: Understanding evidence-based public health policy, Am. J. Public Health 99(9), 1576–1583 (2009)
T.B. Dinh-Zarr, D.A. Sleet, R.A. Shults, S. Zaza, R.W. Elder, J.L. Nichols, R.S. Thompson, D.M. Sosin: The task force on community preventive services: Reviews of evidence regarding interventions to increase the use of safety belts, Am. J. Prev. Med. 21(4), 48–65 (2001)
B. Freeman, S. Chapman, P. Storey: Banning smoking in cars carrying children: An analytical history of a public health advocacy campaign, Aust. N. Z. J. Public Health 32(1), 60–65 (2008)
L. Cornelsen, A. Carreido: Health-Related Taxes on Foods and Beverages (Food Research Collaboration, London 2015)
G. Weisz, A. Cambrosio, P. Keating, L. Knaapen, T. Schlich, V.J. Tournay: The emergence of clinical practice guidelines, Milbank Q. 85(4), 691–727 (2007)
J. Miller: The scottish intercollegiate guidelines network (SIGN), Br. J. Diabetes Vasc. Dis. 2, 47–49 (2002)
National Institute for Health and Care Excellence (NICE): Who we are, https://www.nice.org.uk/about/who-we-are
Haute Autorité de Santé: Contribute to the regulation by quality and efficiency: About HAS, http://www.has-sante.fr/portail/jcms/r_1455134/en/about-has (2013)
Agency for Quality in Medicine (ÄZQ): Nationale VersorgungsLeitlinien (NVL) (National Disease Management Guideline Programme), http://www.leitlinien.de/nvl/
Sistema Nazionale per le Linee Guida (SNLG) (National Guidelines System) and the Istituto Superiore di Sanità (ISS) (National Institute of Health): http://www.snlg-iss.it/home_en
Guías de Práctica Clínica en el Sistema Nacional de Salud (Guides Clinical Practice in the National Health System): http://portal.guiasalud.es/web/guest/guias-practica-clinica
J.M. Grimshaw, I.T. Russell: Effect of clinical guidelines on medical practice: A systematic review of rigorous evaluations, Lancet 342(8883), 1317–1322 (1993)
J. Grant: Evaluating the outcomes of biomedical research on healthcare, Res. Eval. 8(1), 33–38 (1999)
J. Grant, R. Cottrell, F. Cluzeau, G. Fawcett: Evaluating “payback” on biomedical research from papers cited in clinical guidelines: Applied bibliometric study, BMJ 320(7242), 1107–1111 (2000)
G. Lewison, K. Wilcox-Jay: Getting biomedical research into practice: The citations from UK clinical guidelines. In: Proc. 9th ISSI Conf., Beijing (2003) pp. 152–160
G. Lewison, R. Sullivan: The impact of cancer research: How publications influence UK cancer clinical guidelines, Br. J. Cancer 98(12), 1944–1950 (2008)
E. Pallari, A.W. Fox, G. Lewison: Differential research impact in cancer practice guidelines’ evidence base: Lessons from ESMO, NICE and SIGN, ESMO Open 3(1), e000258 (2018)
D. Kryl, L. Allen, K. Dolby, B. Sherbon, I. Viney: Tracking the impact of research on policy and practice: Investigating the feasibility of using citations in clinical guidelines for research evaluation, BMJ Open 2(2), e000897 (2012)
S.M. Noar: A 10-year retrospective of research in health mass media campaigns: Where do we go from here?, J. Health Commun. 11(1), 21–42 (2006)
D.P. Phillips, E.J. Kanter, B. Bednarczyk, P.L. Tastad: Importance of the lay press in the transmission of medical knowledge to the scientific community, N. Engl. J. Med. 325, 1180–1183 (1991)
G. Lewison, S. Tootell, P. Roe, R. Sullivan: How do the media report cancer research? A study of the UK's BBC website, Br. J. Cancer 99(4), 569–576 (2008)
World Health Organization (WHO): Health statistics and information systems—Estimates for 2000–2012, http://www.who.int/healthinfo/global_burden_disease/ estimates/en/index2.html (2012)
G. Lewison, G. Paraje: The classification of biomedical journals by research level, Scientometrics 60(2), 145–157 (2004)
M. Begum, G. Lewison: Web of science research funding information: Methodology for its use in analysis and evaluation, J. Scientometr. Res. 6(2), 65–73 (2017)
V. Bakare, G. Lewison: Country over-citation ratios, Scientometrics 113(2), 1199–1207 (2017)
E. Pallari, G. Lewison, R. Sullivan: How is chronic non-communicable respiratory conditions research reported in European newspapers? An impact assessment for policy, Clin. Respir. J. 11(5), 657–665 (2017)
A.D. Purushotham, G. Lewison, R. Sullivan: The state of research and development in global cancer surgery, Ann. Surg. 255(3), 427–432 (2012)
T.G. Weiser, S.E. Regenbogen, K.D. Thompson, A.B. Haynes, S.R. Lipsitz, W.R. Berry, A.A. Gawande: An estimation of the global volume of surgery: A modelling strategy based on available data, Lancet 372(9633), 139–144 (2008)
M. Begum, G. Lewison, J.S.F. Wright, E. Pallari, R. Sullivan: European non-communicable respiratory disease research, bibliometric study outputs funding, PLoS ONE 11(4), e0154197 (2016)
R. Rajendram, G. Lewison, V.R. Preedy: Worldwide alcohol-related research and the disease burden, Alcohol Alcohol. 41(1), 99–106 (2006)
E. Pallari, G. Lewison, O. Ciani, R. Tarricone, S. Sommariva, M. Begum, R. Sullivan: The impacts of diabetes research from 31 European Countries in 2002 to 2013, Res. Eval. 27(3), 270–282 (2018)
Acknowledgements
This study was supported by the European Commission through the award of a contract to the London School of Economics and Political Science (EC/FP7/602536). It was very materially assisted by the provision of several VBA programs for use with MS Excel for the collection and analysis of data; these were written by Philip Roe of Evaluametrics Ltd. The CPGs and newspaper stories collection, and identification of the cited research studies from the newspapers, was done by the following individuals: for Austria, Germany, and Switzerland: Natalia Kelsch, Anne Spranger, Victor Stephani, and Tobias Schumacher from Technische Universität Berlin, Germany; for Belgium: Ann-Sophie de Mol and Gabrielle Emanuel from King's College London (KCL), UK; for Bulgaria: Eva Nacheva and Christina Tencheva from KCL; for Croatia: Ria Ivandic Emanuel from KCL; for Cyprus: Chryso T. Pallari from the University of Cyprus, Nicosia, Cyprus; for the Czech Republic and Poland: Kasia Zemanek from KCL; for Denmark: Maria Dahl and Maria Emilsson from KCL; for Estonia: Argo Soon from the Estonian Research Council, Tartu, Estonia; for Greece: Laura Mantovani from KCL; for Hungary: Csajbok Edit from Semmelweis University, Budapest, Hungary; for Italy: Ludovica Borsoi from Università Commerciale Luigi Bocconi, Milan, Italy; for Latvia: Ingrid Jaselskyte, Estonian Research Council, Tartu, Estonia; for Luxembourg and the Netherlands: Ann-Sophie de Mol from KCL; for Portugal: Diana Gosálvez-Prados, Elisabeth María Ilidio-Paulo, Camila Higueras-Callejón, and José Carlos Ruiz-Jiménez from Escuela Andaluza de Salud Publica, Granada, Spain; for Romania: Maria-Cristina Juverdeanu from KCL; for Spain: Diana Gosálvez-Prados and Elena Salamanca-Fernández from Escuela Andaluza de Salud Publica, Granada, Spain and Tahereh Dehdarirad from Universitat de Barcelona, Barcelona, Spain; for Sweden: Gustaf Nelhans from the University of Boras, Sweden; for the UK: Argo Soon, Marleen Saidla and Tiina Tasa (Estonia) and Eva Nacheva from KCL partly assisted EP on the datacollection.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Appendix
Appendix
Rights and permissions
Copyright information
© 2019 Springer International Publishing AG, part of Springer Nature
About this chapter
Cite this chapter
Pallari, E., Lewison, G. (2019). How Biomedical Research Can Inform Both Clinicians and the General Public. In: Glänzel, W., Moed, H.F., Schmoch, U., Thelwall, M. (eds) Springer Handbook of Science and Technology Indicators. Springer Handbooks. Springer, Cham. https://doi.org/10.1007/978-3-030-02511-3_22
Download citation
DOI: https://doi.org/10.1007/978-3-030-02511-3_22
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-02510-6
Online ISBN: 978-3-030-02511-3
eBook Packages: Economics and FinanceEconomics and Finance (R0)