Transcriptomics as a First Choice Gate for Fungal Biodegradation Processes Description

  • Alejandro Ledezma-Villanueva
  • José Manuel Adame-Rodríguez
  • Elva T. Aréchiga-CarvajalEmail author
Part of the Nanotechnology in the Life Sciences book series (NALIS)


Environmental impacts of xenobiotic compounds released to air, water, and soil have opened a way for bioremediation to emerge as a green technology that can be safely applied to reduce pollutant concentrations to a minimum in a relative short period of time. “Hard to break” molecules such as asphaltenes, celluloses, and dyes are better treated with mycoremediation techniques. Fungi are higher eukaryotic microorganisms that secrete a good quantity of enzymatic complexes to break covalent bonds on these xenobiotics. As mycoremediation analysis grew, a better understanding of fungal metabolism on extreme environmental conditions is needed to deepen bioremediation-related genes and processes. These can be reached by global molecular approaches such as transcriptomic studies. Until now, limited genomic functional annotations and efficient nucleic acid extractions in bioremediation processes are the main delaying issues in the advancing way to the understanding of these interesting fungal metabolic activities. In this section we expose common technical strategies of RNA extraction protocols and comparison of recent transcriptional studies, as a basic introduction to those interested in applying genomic global approaches, in this area in construction of future efficient application of mycoremediation.


Fungal bioremediation Fungal enzymes Nucleic acid extraction Transcriptomics 


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Copyright information

© Springer Nature Switzerland AG 2018

Authors and Affiliations

  • Alejandro Ledezma-Villanueva
    • 1
  • José Manuel Adame-Rodríguez
    • 1
  • Elva T. Aréchiga-Carvajal
    • 1
    Email author
  1. 1.Unidad de Manipulación Genética, Laboratorio de Micología y Fitopatología, Departamento de Microbiología, Facultad de Ciencias BiológicasUniversidad Autónoma de Nuevo León, Cd. UniversitariaSan Nicolás de los GarzaMexico

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