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The Origin of a New Progenitor Stem Cell Group in Human Development

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The Origin of a New Progenitor Stem Cell Group in Human Development

Part of the book series: Advances in Anatomy, Embryology and Cell Biology ((ADVSANAT,volume 230))

Abstract

The observation of two precursor groups of the early stem cells (Groups I and II) leads to the realization that a first amount of fetal stem cells (Group I) migrate from the AMG (Aortal-Mesonephric-Gonadal)-region into the aorta and its branching vessels. A second group (Group II) gains quite a new significance during human development. This group presents a specific developmental step which is found only in the human. This continuation of the early development along a different way indicates a general alteration of the stem cell biology. This changed process in the stem cell scene dominates the further development of the human stem cells. It remains unclear where this phylogenetic step first appears. By far not all advanced mammals show this second group of stem cells and their axonal migration. Essentially only primates seem to be involved in this special development.

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Authors and Affiliations

  1. Department of Anatomy and Cell Biology, Institute of Anatomy, University of Bonn, Bonn, Germany

    Hubert Wartenberg

  2. Department of Neuroanatomy, Institute of Anatomy, University of Bonn, Bonn, Germany

    Andreas Miething

  3. Department of Cellular and Molecular Medicine, University of Copenhagen, København N, Denmark

    Kjeld Møllgård

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Wartenberg, H., Miething, A., Møllgård, K. (2019). The Origin of a New Progenitor Stem Cell Group in Human Development. In: The Origin of a New Progenitor Stem Cell Group in Human Development. Advances in Anatomy, Embryology and Cell Biology, vol 230. Springer, Cham. https://doi.org/10.1007/978-3-030-02050-7_1

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